2,4-thiazolidinedione has been researched along with Liver Steatosis in 4 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone treatment improves insulin resistance (IR), glucose metabolism, hepatic steatosis, and necroinflammation in patients with nonalcoholic steatohepatitis (NASH)." | 2.74 | Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis. ( Balas, B; Belfort-Aguilar, R; Cusi, K; Gastaldelli, A; Hardies, LJ; Harrison, SA; Schenker, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takei, Y | 1 |
| Martins, FO | 1 |
| Delgado, TC | 1 |
| Viegas, J | 1 |
| Gaspar, JM | 1 |
| Scott, DK | 1 |
| O'Doherty, RM | 1 |
| Macedo, MP | 1 |
| Jones, JG | 1 |
| Gastaldelli, A | 1 |
| Harrison, SA | 2 |
| Belfort-Aguilar, R | 1 |
| Hardies, LJ | 1 |
| Balas, B | 1 |
| Schenker, S | 1 |
| Cusi, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Role of Pioglitazone in the Treatment of Non-alcoholic Steatohepatitis (NASH)[NCT00227110] | Phase 4 | 55 participants (Actual) | Interventional | 2002-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 2,4-thiazolidinedione and Liver Steatosis
| Article | Year |
|---|---|
Treatment of non-alcoholic fatty liver disease.
Topics: Animals; Fatty Liver; Humans; Inflammation; Insulin Resistance; Life Style; Liver Transplantation; M | 2013 |
1 trial available for 2,4-thiazolidinedione and Liver Steatosis
| Article | Year |
|---|---|
Importance of changes in adipose tissue insulin resistance to histological response during thiazolidinedione treatment of patients with nonalcoholic steatohepatitis.
Topics: Adipose Tissue; Adult; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Fatty Acids, N | 2009 |
2 other studies available for 2,4-thiazolidinedione and Liver Steatosis
| Article | Year |
|---|---|
Mechanisms by which the thiazolidinedione troglitazone protects against sucrose-induced hepatic fat accumulation and hyperinsulinaemia.
Topics: Animals; Chromans; Fatty Liver; Hyperinsulinism; Hypoglycemic Agents; Male; Protective Agents; Rats; | 2016 |
Thiazolidinedione therapy for nonalcoholic steatohepatitis: go, stop, or proceed with caution?
Topics: Fatty Liver; Humans; Hypoglycemic Agents; Thiazolidinediones | 2010 |