2,4-thiazolidinedione has been researched along with Liver Failure in 2 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Troglitazone (TGZ) is an orally active hypoglycemic agent which is used for the treatment of non-insulin-dependent diabetes mellitus." | 1.36 | Investigation of the role of the thiazolidinedione ring of troglitazone in inducing hepatotoxicity. ( Chan, EC; Chui, WK; Ho, HK; New, LS; Saha, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saha, S | 1 |
| New, LS | 1 |
| Ho, HK | 1 |
| Chui, WK | 1 |
| Chan, EC | 1 |
| Isley, WL | 1 |
| Oki, JC | 1 |
1 review available for 2,4-thiazolidinedione and Liver Failure
| Article | Year |
|---|---|
Hepatotoxicity of thiazolidinediones.
Topics: Humans; Hypoglycemic Agents; Liver; Liver Failure; Liver Transplantation; Thiazoles; Thiazolidinedio | 2001 |
1 other study available for 2,4-thiazolidinedione and Liver Failure
| Article | Year |
|---|---|
Investigation of the role of the thiazolidinedione ring of troglitazone in inducing hepatotoxicity.
Topics: Cell Line; Cell Survival; Chromans; Drug Stability; Glutathione; Hepatocytes; Humans; Hypoglycemic A | 2010 |