2,4-thiazolidinedione has been researched along with Glucose Intolerance in 5 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
Glucose Intolerance: A pathological state in which BLOOD GLUCOSE level is less than approximately 140 mg/100 ml of PLASMA at fasting, and above approximately 200 mg/100 ml plasma at 30-, 60-, or 90-minute during a GLUCOSE TOLERANCE TEST. This condition is seen frequently in DIABETES MELLITUS, but also occurs with other diseases and MALNUTRITION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In impaired glucose tolerance subjects, these procedures were performed before and after treatment with pioglitazone or metformin." | 3.74 | Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation. ( Bodles, AM; Fried, SK; Kern, LM; Kern, PA; Lee, MJ; McGehee, RE; Phanavanh, B; Rasouli, N; Spencer, HJ; Starks, T; Varma, V; Yao-Borengasser, A, 2007) |
| "Diabetes mellitus is a chronic disease that leads to complications including heart disease, stroke, kidney failure, blindness and nerve damage." | 1.31 | The hormone resistin links obesity to diabetes. ( Ahima, RS; Bailey, ST; Banerjee, RR; Bhat, S; Brown, EJ; Lazar, MA; Patel, HR; Steppan, CM; Wright, CM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rissanen, A | 1 |
| Howard, CP | 1 |
| Botha, J | 1 |
| Thuren, T | 1 |
| Iwamoto, Y | 1 |
| Varma, V | 1 |
| Yao-Borengasser, A | 1 |
| Rasouli, N | 1 |
| Bodles, AM | 1 |
| Phanavanh, B | 1 |
| Lee, MJ | 1 |
| Starks, T | 1 |
| Kern, LM | 1 |
| Spencer, HJ | 1 |
| McGehee, RE | 1 |
| Fried, SK | 1 |
| Kern, PA | 1 |
| Steppan, CM | 1 |
| Bailey, ST | 1 |
| Bhat, S | 1 |
| Brown, EJ | 1 |
| Banerjee, RR | 1 |
| Wright, CM | 1 |
| Patel, HR | 1 |
| Ahima, RS | 1 |
| Lazar, MA | 1 |
| Smith, U | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of Insulin Sensitizers in Subjects With Impaired Glucose Tolerance[NCT00108615] | Phase 4 | 48 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
| Relationship Between Obesity and Periodontal Disease[NCT02508415] | 62 participants (Actual) | Interventional | 2013-02-28 | Completed | |||
| Effectiveness of the Treatment With Dapagliflozin and Metformin Compared to Metformin Monotherapy for Weight Loss on Diabetic and Prediabetic Patients With Obesity Class III[NCT03968224] | Phase 2/Phase 3 | 90 participants (Anticipated) | Interventional | 2018-07-07 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for 2,4-thiazolidinedione and Glucose Intolerance
| Article | Year |
|---|---|
[Selection of oral antidiabetic drugs].
Topics: Acarbose; Administration, Oral; Biguanides; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Enzy | 2005 |
Impaired ('diabetic') insulin signaling and action occur in fat cells long before glucose intolerance--is insulin resistance initiated in the adipose tissue?
Topics: Adipocytes; Diabetes Mellitus; Diabetes Mellitus, Type 2; Glucose Intolerance; Humans; Insulin; Insu | 2002 |
1 trial available for 2,4-thiazolidinedione and Glucose Intolerance
| Article | Year |
|---|---|
Effect of anti-IL-1β antibody (canakinumab) on insulin secretion rates in impaired glucose tolerance or type 2 diabetes: results of a randomized, placebo-controlled trial.
Topics: Adolescent; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Blood Glucose; D | 2012 |
2 other studies available for 2,4-thiazolidinedione and Glucose Intolerance
| Article | Year |
|---|---|
Human visfatin expression: relationship to insulin sensitivity, intramyocellular lipids, and inflammation.
Topics: Abdominal Fat; Biomarkers; Biopsy; Body Mass Index; Cytokines; Gene Expression; Glucose Intolerance; | 2007 |
The hormone resistin links obesity to diabetes.
Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Base Sequence; Chromosomes, Human, Pair 19; Clo | 2001 |
The hormone resistin links obesity to diabetes.
Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Base Sequence; Chromosomes, Human, Pair 19; Clo | 2001 |
The hormone resistin links obesity to diabetes.
Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Base Sequence; Chromosomes, Human, Pair 19; Clo | 2001 |
The hormone resistin links obesity to diabetes.
Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Base Sequence; Chromosomes, Human, Pair 19; Clo | 2001 |