2,4-thiazolidinedione has been researched along with Compensatory Hyperinsulinemia in 5 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
Compensatory Hyperinsulinemia: A GLUCOSE-induced HYPERINSULINEMIA, a marker of insulin-resistant state. It is a mechanism to compensate for reduced sensitivity to insulin.
| Excerpt | Relevance | Reference |
|---|---|---|
| "For now, the goals and methods of treating hypertension and dyslipidemia are the same in people with the metabolic syndrome as in the general population." | 2.41 | A truly deadly quartet: obesity, hypertension, hypertriglyceridemia, and hyperinsulinemia. ( Hoogwerf, BJ; Nambi, V; Sprecher, DL, 2002) |
| "In untreated rats insulin sensitivity decreased by 46% over 3-6 h of elevated FFA, whereas it remained normal but with a 50% increase in FFA clearance in Pio-treated rats." | 1.31 | Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: role of the liver. ( Cooney, GJ; Dzamko, N; Ellis, B; Frangioudakis, G; Furler, SM; Iglesias, MA; Kraegen, EW; Ye, JM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (80.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martins, FO | 1 |
| Delgado, TC | 1 |
| Viegas, J | 1 |
| Gaspar, JM | 1 |
| Scott, DK | 1 |
| O'Doherty, RM | 1 |
| Macedo, MP | 1 |
| Jones, JG | 1 |
| Ye, JM | 1 |
| Frangioudakis, G | 1 |
| Iglesias, MA | 1 |
| Furler, SM | 1 |
| Ellis, B | 1 |
| Dzamko, N | 1 |
| Cooney, GJ | 1 |
| Kraegen, EW | 1 |
| Nambi, V | 1 |
| Hoogwerf, BJ | 1 |
| Sprecher, DL | 1 |
| Uwaifo, GI | 1 |
| Ratner, RE | 1 |
| Taylor, AE | 1 |
3 reviews available for 2,4-thiazolidinedione and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
A truly deadly quartet: obesity, hypertension, hypertriglyceridemia, and hyperinsulinemia.
Topics: Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Hyperinsulinism; Hypertension; Hypertrigly | 2002 |
The roles of insulin resistance, hyperinsulinemia, and thiazolidinediones in cardiovascular disease.
Topics: Cardiovascular Diseases; Humans; Hyperinsulinism; Insulin Resistance; Receptors, Cytoplasmic and Nuc | 2003 |
Insulin-lowering medications in polycystic ovary syndrome.
Topics: Diazoxide; Female; Humans; Hyperandrogenism; Hyperinsulinism; Hypoglycemic Agents; Insulin Resistanc | 2000 |
2 other studies available for 2,4-thiazolidinedione and Compensatory Hyperinsulinemia
| Article | Year |
|---|---|
Mechanisms by which the thiazolidinedione troglitazone protects against sucrose-induced hepatic fat accumulation and hyperinsulinaemia.
Topics: Animals; Chromans; Fatty Liver; Hyperinsulinism; Hypoglycemic Agents; Male; Protective Agents; Rats; | 2016 |
Prior thiazolidinedione treatment preserves insulin sensitivity in normal rats during acute fatty acid elevation: role of the liver.
Topics: Acyl Coenzyme A; Adiponectin; Animals; Blood Glucose; Fat Emulsions, Intravenous; Fatty Acids, Nones | 2002 |