2,4-thiazolidinedione has been researched along with Colonic Neoplasms in 7 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cotreatment with GW9662 (GW), a PPARgamma antagonist, significantly inhibited this effect, whereas overexpressing the receptor enhanced it." | 1.35 | PPARgamma1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells. ( Allred, CD; Kilgore, MW; Southard, RC; Talbert, DR; Wang, X, 2008) |
| "For this purpose, human colon cancer cells (HT29) were grown in severe combined immunodeficient mice." | 1.32 | Limited tumor growth (HT29) in vivo under RO205-2349 is due to increased apoptosis and reduced cell volume but not to decreased proliferation rate. ( Bauer, S; Feldhaus, S; Katoh, M; Schnitzer, T; Schumacher, U, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Yoon, JK | 1 |
| Byeon, HE | 1 |
| Ko, SA | 1 |
| Park, BN | 1 |
| An, YS | 1 |
| Lee, HY | 1 |
| Lee, YW | 1 |
| Lee, SJ | 1 |
| Lewis, JD | 1 |
| Capra, AM | 1 |
| Achacoso, NS | 1 |
| Ferrara, A | 1 |
| Levin, TR | 1 |
| Quesenberry, CP | 1 |
| Habel, LA | 1 |
| Katoh, M | 1 |
| Feldhaus, S | 1 |
| Schnitzer, T | 1 |
| Bauer, S | 1 |
| Schumacher, U | 1 |
| Yoshizumi, T | 1 |
| Ohta, T | 1 |
| Ninomiya, I | 1 |
| Terada, I | 1 |
| Fushida, S | 1 |
| Fujimura, T | 1 |
| Nishimura, G | 1 |
| Shimizu, K | 1 |
| Yi, S | 1 |
| Miwa, K | 1 |
| Allred, CD | 1 |
| Talbert, DR | 1 |
| Southard, RC | 1 |
| Wang, X | 1 |
| Kilgore, MW | 1 |
| Yanase, T | 1 |
| Roberts-Thomson, SJ | 1 |
2 reviews available for 2,4-thiazolidinedione and Colonic Neoplasms
| Article | Year |
|---|---|
[Physiological function of peroxisome proliferator-activated receptor].
Topics: Animals; Blood Cells; Cell Differentiation; Cell Division; Colonic Neoplasms; Diabetes Mellitus, Typ | 1999 |
Peroxisome proliferator-activated receptors in tumorigenesis: targets of tumour promotion and treatment.
Topics: Animals; Cell Cycle; Cell Differentiation; Colonic Neoplasms; Humans; Lipid Metabolism; Liver Neopla | 2000 |
5 other studies available for 2,4-thiazolidinedione and Colonic Neoplasms
| Article | Year |
|---|---|
Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon cancer.
Topics: Animals; Antineoplastic Agents; Cell Cycle Checkpoints; Colonic Neoplasms; Cyclin D1; Cyclin-Depende | 2020 |
Thiazolidinedione therapy is not associated with increased colonic neoplasia risk in patients with diabetes mellitus.
Topics: Aged; California; Colonic Neoplasms; Colonoscopy; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type | 2008 |
Limited tumor growth (HT29) in vivo under RO205-2349 is due to increased apoptosis and reduced cell volume but not to decreased proliferation rate.
Topics: Animals; Apoptosis; Carcinoembryonic Antigen; Cell Differentiation; Cell Division; Cell Size; Coloni | 2004 |
Thiazolidinedione, a peroxisome proliferator-activated receptor-gamma ligand, inhibits growth and metastasis of HT-29 human colon cancer cells through differentiation-promoting effects.
Topics: Animals; Antineoplastic Agents; beta Catenin; Cadherins; Cell Cycle; Cell Cycle Proteins; Cell Diffe | 2004 |
PPARgamma1 as a molecular target of eicosapentaenoic acid in human colon cancer (HT-29) cells.
Topics: Anilides; Cell Proliferation; Colonic Neoplasms; Eicosapentaenoic Acid; Gene Expression Regulation; | 2008 |