2,4-thiazolidinedione has been researched along with Breast Neoplasms in 4 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
Breast Neoplasms: Tumors or cancer of the human BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here we demonstrate that human breast cancer cells, but not normal mammary epithelial cells, are dramatically sensitized to TRAIL-induced apoptosis and caspase activation by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists of the thiazolidinedione (TZD) class." | 1.33 | Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest. ( Chen, F; Cryns, VL; Freedman, B; Jameson, JL; Jordan, VC; Kwan, T; Lee, EJ; Lu, M; Schafer, JM; Yu, C, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Metwally, K | 1 |
| Pratsinis, H | 1 |
| Kletsas, D | 1 |
| Patil, V | 1 |
| Tilekar, K | 1 |
| Mehendale-Munj, S | 1 |
| Mohan, R | 1 |
| Ramaa, CS | 1 |
| Lu, M | 1 |
| Kwan, T | 1 |
| Yu, C | 1 |
| Chen, F | 1 |
| Freedman, B | 1 |
| Schafer, JM | 1 |
| Lee, EJ | 1 |
| Jameson, JL | 1 |
| Jordan, VC | 1 |
| Cryns, VL | 1 |
| Russell, AJ | 1 |
| Westwood, IM | 1 |
| Crawford, MH | 1 |
| Robinson, J | 1 |
| Kawamura, A | 1 |
| Redfield, C | 1 |
| Laurieri, N | 1 |
| Lowe, ED | 1 |
| Davies, SG | 1 |
| Sim, E | 1 |
4 other studies available for 2,4-thiazolidinedione and Breast Neoplasms
| Article | Year |
|---|---|
Novel 2,4- thiazolidinediones: Synthesis, in vitro cytotoxic activity, and mechanistic investigation.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Fem | 2017 |
Synthesis and primary cytotoxicity evaluation of new 5-benzylidene-2,4-thiazolidinedione derivatives.
Topics: Antineoplastic Agents; Benzylidene Compounds; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation | 2010 |
Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; | 2005 |
Selective small molecule inhibitors of the potential breast cancer marker, human arylamine N-acetyltransferase 1, and its murine homologue, mouse arylamine N-acetyltransferase 2.
Topics: Animals; Arylamine N-Acetyltransferase; Binding Sites; Biomarkers, Tumor; Breast Neoplasms; Enzyme I | 2009 |