2,4-thiazolidinedione has been researched along with Bone Loss, Osteoclastic in 3 studies
thiazolidine-2,4-dione: structure in first source
1,3-thiazolidine-2,4-dione : A thiazolidenedione carrying oxo substituents at positions 2 and 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we examined the changes in both cancellous and cortical bone of 6-month-old male mice treated with darglitazone, a potent and selective PPARgamma agonist, at 10 mg/kg/day by dosing the compound in a food mixture for 2 or 8 weeks." | 1.33 | Surface-specific effects of a PPARgamma agonist, darglitazone, on bone in mice. ( Brown, TA; Healy, DR; Ke, HZ; Li, M; Li, Y; Pan, LC; Robinson, BS; Simmons, HA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, M | 1 |
| Pan, LC | 1 |
| Simmons, HA | 1 |
| Li, Y | 1 |
| Healy, DR | 1 |
| Robinson, BS | 1 |
| Ke, HZ | 1 |
| Brown, TA | 1 |
| Yaturu, S | 1 |
| Bryant, B | 1 |
| Jain, SK | 1 |
| Schwartz, AV | 1 |
| Sellmeyer, DE | 1 |
3 other studies available for 2,4-thiazolidinedione and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Surface-specific effects of a PPARgamma agonist, darglitazone, on bone in mice.
Topics: Adipogenesis; Alkaline Phosphatase; Animals; Body Weight; Bone and Bones; Bone Density; Bone Marrow | 2006 |
Thiazolidinedione treatment decreases bone mineral density in type 2 diabetic men.
Topics: Bone Density; Bone Resorption; Diabetes Mellitus, Type 2; Fractures, Bone; Humans; Hypoglycemic Agen | 2007 |
Thiazolidinedione therapy gets complicated: is bone loss the price of improved insulin resistance?
Topics: Bone Density; Bone Resorption; Diabetes Mellitus, Type 2; Fractures, Bone; Humans; Hypoglycemic Agen | 2007 |