2,4-dinitrophenol has been researched along with Pregnancy in 22 studies
2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nitrofen was administered on embryonic day (ED)9 and fetal TO was performed on ED18." | 1.91 | Lung proliferation is dependent on the duration not the timepoint of tracheal occlusion in nitrofen rats with diaphragmatic hernia. ( Beck, V; Deckx, S; Deprest, JA; Deprest, T; Froyen, G; Plevoets, K; Sandaite, I, 2023) |
| " These data indicate that dinoseb is teratogenic at maternally toxic doses, but the exposure range of dinoseb at which malformations occur seems to be narrow." | 1.36 | Prenatal developmental toxicity of gavage or feeding doses of 2-sec-butyl-4,6-dinitrophenol in rats. ( Ema, M; Fujii, S; Hirose, A; Matsumoto, M, 2010) |
| "In a combined repeated dose toxicity study with reproduction/developmental toxicity screening test, Crj:CD(SD)IGS rats were dosed with dinoseb, 2-sec-butyl-4,6-dinitrophenol, by gavage at 0 (vehicle), 0." | 1.35 | Combined repeated dose and reproductive/developmental toxicity screening test of the nitrophenolic herbicide dinoseb, 2-sec-butyl-4,6-dinitrophenol, in rats. ( Ema, M; Furuhashi, T; Matsumoto, M; Poncipe, C, 2008) |
| " Males were dosed for 46 days, beginning 14 days before mating, and females were dosed for 40-47 days, from 14 days before mating to day 3 of lactation." | 1.35 | Reproductive and developmental toxicity screening study of 2,4-dinitrophenol in rats. ( Ema, M; Hirata-Koizumi, M; Hirose, A; Kamata, E; Sunaga, M; Takahashi, M, 2009) |
| "[14C]Dinoseb was applied to previously clipped back skin of 33- and 82-day-old female Fischer 344 rats at a dosage range of 210-2680 nmol/cm2." | 1.28 | Age-related percutaneous penetration of 2-sec-butyl-4,6-dinitrophenol (dinoseb) in rats. ( Fisher, HL; Hall, LL; Hughes, MF; Shah, PV; Sumler, MR, 1992) |
| "Colchicine treatment had no effect on body weight or kidney weight." | 1.27 | Functional teratogens of the rat kidney. I. Colchicine, dinoseb, and methyl salicylate. ( Carver, B; Daston, GP; Kavlock, RJ; Rehnberg, BF; Rogers, EH, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (50.00) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 3 (13.64) | 24.3611 |
| 2020's | 2 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Beck, V | 1 |
| Froyen, G | 1 |
| Deckx, S | 1 |
| Sandaite, I | 1 |
| Deprest, T | 1 |
| Plevoets, K | 1 |
| Deprest, JA | 1 |
| Doktor, F | 1 |
| Figueira, RL | 1 |
| Khalaj, K | 1 |
| Ijaz, A | 1 |
| Lacher, M | 1 |
| Blundell, M | 1 |
| Antounians, L | 1 |
| Zani, A | 1 |
| Samaiya, PK | 1 |
| Narayan, G | 1 |
| Kumar, A | 1 |
| Krishnamurthy, S | 1 |
| Matsumoto, M | 2 |
| Fujii, S | 1 |
| Hirose, A | 2 |
| Ema, M | 3 |
| Padalko, VI | 1 |
| Leonova, IS | 1 |
| Kozlova, EV | 1 |
| Furuhashi, T | 1 |
| Poncipe, C | 1 |
| Takahashi, M | 1 |
| Sunaga, M | 1 |
| Hirata-Koizumi, M | 1 |
| Kamata, E | 1 |
| Beaudoin, AR | 1 |
| Fisher, DL | 1 |
| Wakai, K | 1 |
| Tsushima, T | 1 |
| Isozaki, O | 1 |
| Sato, Y | 1 |
| Sato, K | 1 |
| Shizume, K | 1 |
| Weisbecker, U | 1 |
| Ibbotson, GE | 1 |
| Livesey, G | 1 |
| Williams, KE | 1 |
| Meigs, RA | 1 |
| Moorthy, KB | 1 |
| Pratten, MK | 2 |
| Cable, HC | 1 |
| Ringsdorf, H | 1 |
| Lloyd, JB | 2 |
| Streeter, ML | 1 |
| Rosso, P | 1 |
| Perks, AM | 1 |
| Ruiz, T | 1 |
| Chua, B | 1 |
| Vonder Muhll, I | 1 |
| Kindler, PM | 1 |
| Blair, W | 1 |
| Takahashi, T | 1 |
| Utoguchi, N | 1 |
| Takara, A | 1 |
| Yamamoto, N | 1 |
| Nakanishi, T | 1 |
| Tanaka, K | 1 |
| Audus, KL | 1 |
| Watanabe, Y | 1 |
| Hall, LL | 1 |
| Fisher, HL | 1 |
| Sumler, MR | 1 |
| Hughes, MF | 1 |
| Shah, PV | 1 |
| Giavini, E | 2 |
| Broccia, ML | 2 |
| Prati, M | 2 |
| Cova, D | 1 |
| Rossini, L | 1 |
| Daston, GP | 1 |
| Rehnberg, BF | 1 |
| Carver, B | 1 |
| Rogers, EH | 1 |
| Kavlock, RJ | 1 |
| Bersinger, NA | 1 |
| Malek, A | 1 |
| Benz, B | 1 |
| Keller, PJ | 1 |
| Schneider, H | 1 |
| Vismara, C | 1 |
| Gibson, JE | 1 |
22 other studies available for 2,4-dinitrophenol and Pregnancy
| Article | Year |
|---|---|
Lung proliferation is dependent on the duration not the timepoint of tracheal occlusion in nitrofen rats with diaphragmatic hernia.
Topics: Airway Obstruction; Animals; Cell Proliferation; Female; Hernias, Diaphragmatic, Congenital; Lung; P | 2023 |
Characterization of the congenital diaphragmatic hernia model in C57BL/6J fetal mice: a step toward lineage tracing experiments.
Topics: Animals; Female; Fetus; Hernias, Diaphragmatic, Congenital; Humans; Mice; Mice, Inbred C57BL; Pregna | 2023 |
2,4 Dinitrophenol Attenuates Mitochondrial Dysfunction and Improves Neurobehavioral Outcomes Postanoxia in Neonatal Rats.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Animals, Newborn; bcl-2-Associated X Protein; Ca | 2018 |
Prenatal developmental toxicity of gavage or feeding doses of 2-sec-butyl-4,6-dinitrophenol in rats.
Topics: 2,4-Dinitrophenol; Animals; Enteral Nutrition; Female; Fetal Weight; Fetus; Male; Musculoskeletal Ab | 2010 |
[The effect of 2,4-dinitrophenol on the intensity of oxidative processes in the rat liver during prolonged experiment].
Topics: 2,4-Dinitrophenol; Aging; Animals; Electron Transport; Female; Liver; Liver Function Tests; Male; Ma | 2010 |
Combined repeated dose and reproductive/developmental toxicity screening test of the nitrophenolic herbicide dinoseb, 2-sec-butyl-4,6-dinitrophenol, in rats.
Topics: 2,4-Dinitrophenol; Administration, Oral; Animals; Body Weight; Drug Synergism; Female; Hematopoiesis | 2008 |
Reproductive and developmental toxicity screening study of 2,4-dinitrophenol in rats.
Topics: 2,4-Dinitrophenol; Abnormalities, Drug-Induced; Animals; Animals, Newborn; Body Weight; Female; Live | 2009 |
An in vivo/in vitro evaluation of teratogenic action.
Topics: 2,4-Dinitrophenol; Animals; Arsenates; Cadmium; Culture Techniques; Dinitrophenols; Embryo, Mammalia | 1981 |
Processing of human growth hormone by rat hepatocytes in monolayer culture.
Topics: 2,4-Dinitrophenol; Animals; Cells, Cultured; Chloroquine; Chromatography, Gel; Dinitrophenols; Femal | 1984 |
The fate of homologous 125I-labelled immunoglobulin G within rat visceral yolk sacs incubated in vitro.
Topics: 2,4-Dinitrophenol; Ammonium Chloride; Animals; Dinitrophenols; Female; Immunoglobulin G; In Vitro Te | 1983 |
The support of steroid aromatization by mitochondrial metabolic activities of the human placenta.
Topics: 2,4-Dinitrophenol; Aromatase; Dinitrophenols; Female; Hexokinase; Humans; Mitochondria; Oligomycins; | 1984 |
Adsorptive pinocytosis of polycationic copolymers of vinylpyrrolidone with vinylamine by rat yolk sac and rat peritoneal macrophage.
Topics: 2,4-Dinitrophenol; Animals; Cold Temperature; Dinitrophenols; Female; Kinetics; Macrophages; Molecul | 1982 |
Transport mechanisms for ascorbic acid in the human placenta.
Topics: 2,4-Dinitrophenol; Ascorbic Acid; Biological Transport; Dehydroascorbic Acid; Dinitrophenols; Female | 1981 |
Reabsorption of lung liquid produced by 2,4-dinitrophenol in in vitro lungs from fetal guinea pigs.
Topics: 2,4-Dinitrophenol; Absorption; Amiloride; Animals; Dinitrophenols; Extravascular Lung Water; Female; | 1993 |
Uptake of microparticles by rat visceral yolk sac.
Topics: 2,4-Dinitrophenol; Animals; Calcium Chloride; Culture Techniques; Egtazic Acid; Endocytosis; Female; | 1997 |
Carrier-mediated transport of folic acid in BeWo cell monolayers as a model of the human trophoblast.
Topics: 2,4-Dinitrophenol; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Anions; Biological Transport; C | 2001 |
Age-related percutaneous penetration of 2-sec-butyl-4,6-dinitrophenol (dinoseb) in rats.
Topics: 2,4-Dinitrophenol; Aging; Animals; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dinit | 1992 |
Teratogenicity of dinoseb: role of the diet.
Topics: 2,4-Dinitrophenol; Animals; Diet; Dinitrophenols; Female; Fetus; Herbicides; Pregnancy; Rats; Terato | 1989 |
Functional teratogens of the rat kidney. I. Colchicine, dinoseb, and methyl salicylate.
Topics: 2,4-Dinitrophenol; Animals; Animals, Suckling; Colchicine; Deamino Arginine Vasopressin; Dinitrophen | 1988 |
Effect of protein synthesis inhibitors and metabolic blockers on the production of placental proteins by the in vitro perfused human placenta.
Topics: 2,4-Dinitrophenol; Antimetabolites; Cycloheximide; Dinitrophenols; Female; Humans; In Vitro Techniqu | 1988 |
Effect of method of administration on the teratogenicity of dinoseb in the rat.
Topics: 2,4-Dinitrophenol; Animals; Dinitrophenols; Female; Pregnancy; Rats; Teratogens | 1986 |
Teratology studies in mice with 2-sec-butyl-4,6-dinitrophenol (dinoseb).
Topics: 2,4-Dinitrophenol; Abnormalities, Drug-Induced; Animals; Bone and Bones; Cesarean Section; Dinitroph | 1973 |