2,4-dinitrophenol has been researched along with Parkinson Disease in 3 studies
2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kishimoto, Y | 1 |
| Johnson, J | 1 |
| Fang, W | 1 |
| Halpern, J | 1 |
| Marosi, K | 1 |
| Liu, D | 1 |
| Geisler, JG | 1 |
| Mattson, MP | 1 |
| Lee, Y | 1 |
| Heo, G | 1 |
| Lee, KM | 1 |
| Kim, AH | 1 |
| Chung, KW | 1 |
| Im, E | 1 |
| Chung, HY | 1 |
| Lee, J | 1 |
| Choi, J | 1 |
| Sullards, MC | 1 |
| Olzmann, JA | 1 |
| Rees, HD | 1 |
| Weintraub, ST | 1 |
| Bostwick, DE | 1 |
| Gearing, M | 1 |
| Levey, AI | 1 |
| Chin, LS | 1 |
| Li, L | 1 |
3 other studies available for 2,4-dinitrophenol and Parkinson Disease
| Article | Year |
|---|---|
A mitochondrial uncoupler prodrug protects dopaminergic neurons and improves functional outcome in a mouse model of Parkinson's disease.
Topics: 2,4-Dinitrophenol; Animals; Cell Death; Disease Models, Animal; Dopaminergic Neurons; Mice, Inbred C | 2020 |
Neuroprotective effects of 2,4-dinitrophenol in an acute model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 2,4-Dinitrophenol; Animals; Cell Death; Dinitrophenols | 2017 |
Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases.
Topics: 2,4-Dinitrophenol; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Blotting, Wester | 2006 |