Page last updated: 2024-10-21

2,4-dinitrophenol and Methemoglobinemia

2,4-dinitrophenol has been researched along with Methemoglobinemia in 2 studies

2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.

Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects."6.472,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. ( Dargan, PI; El-Zanfaly, M; Grundlingh, J; Wood, DM, 2011)
"2,4-Dinitrophenol (DNP) is reported to cause rapid loss of weight, but unfortunately is associated with an unacceptably high rate of significant adverse effects."2.472,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death. ( Dargan, PI; El-Zanfaly, M; Grundlingh, J; Wood, DM, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Duflou, J1
Grundlingh, J1
Dargan, PI1
El-Zanfaly, M1
Wood, DM1

Reviews

1 review available for 2,4-dinitrophenol and Methemoglobinemia

ArticleYear
2,4-dinitrophenol (DNP): a weight loss agent with significant acute toxicity and risk of death.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2011, Volume: 7, Issue:3

    Topics: 2,4-Dinitrophenol; Anti-Obesity Agents; Drug Overdose; Female; Hemofiltration; Humans; Illicit Drugs

2011

Other Studies

1 other study available for 2,4-dinitrophenol and Methemoglobinemia

ArticleYear
A case of fatal 2,4-dinitrophenol (2,4-DNP) intoxication with delayed onset methaemoglobinaemia.
    Pathology, 2019, Volume: 51, Issue:5

    Topics: 2,4-Dinitrophenol; Alcohol Drinking; Autopsy; Fatal Outcome; Humans; Male; Methemoglobinemia; N-Meth

2019