2,4-dinitrophenol has been researched along with Heart Disease, Ischemic in 8 studies
2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The purpose of this study was to investigate the roles of loss of oxidative phosphorylation and activation of the mitochondrial ATP-sensitive K+ channel and permeability transition pore in VF development during myocardial ischemia by using mitochondrial uncoupling agents (carbonyl cyanide m-chlorophenylhydrazone and 2,4-dinitrophenol) and channel blockers (5-hydroxydecanoate and cyclosporine A) at concentrations that have been demonstrated to block the intended targets selectively." | 3.77 | Mitochondrial uncoupling agents trigger ventricular fibrillation in isolated rat hearts. ( Alderson, JM; Clements-Jewery, H; Hatcher, AS, 2011) |
| " omeiensis and puerarin on the fever induced by 2,4-dinitrophenol in rats were very fast and significant, maintaining for about 8 hours, while the effect of P." | 3.69 | [Comparative study on pharmacological effects of various species of Pueraria]. ( Chen, H; Cheng, B; Jiang, J; Su, X; Zhou, Y, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hatcher, AS | 1 |
| Alderson, JM | 1 |
| Clements-Jewery, H | 1 |
| Rainbow, RD | 1 |
| Lodwick, D | 1 |
| Hudman, D | 1 |
| Davies, NW | 1 |
| Norman, RI | 1 |
| Standen, NB | 1 |
| Hausenloy, D | 1 |
| Wynne, A | 1 |
| Duchen, M | 1 |
| Yellon, D | 1 |
| Mylotte, LA | 1 |
| Duffy, AM | 1 |
| Murphy, M | 1 |
| O'Brien, T | 1 |
| Samali, A | 1 |
| Barry, F | 1 |
| Szegezdi, E | 1 |
| Zhou, Y | 1 |
| Su, X | 1 |
| Cheng, B | 1 |
| Jiang, J | 1 |
| Chen, H | 1 |
| Kupriyanov, VV | 1 |
| Xiang, B | 1 |
| Kuzio, B | 1 |
| Deslauriers, R | 1 |
| Tsutsumi, Y | 1 |
| Oshita, S | 1 |
| Kitahata, H | 1 |
| Kuroda, Y | 1 |
| Kawano, T | 1 |
| Nakaya, Y | 1 |
| Mejía-Alvarez, R | 1 |
| Marban, E | 1 |
8 other studies available for 2,4-dinitrophenol and Heart Disease, Ischemic
| Article | Year |
|---|---|
Mitochondrial uncoupling agents trigger ventricular fibrillation in isolated rat hearts.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cyclo | 2011 |
SUR2A C-terminal fragments reduce KATP currents and ischaemic tolerance of rat cardiac myocytes.
Topics: 2,4-Dinitrophenol; Action Potentials; Animals; Antimetabolites; ATP-Binding Cassette Transporters; C | 2004 |
Transient mitochondrial permeability transition pore opening mediates preconditioning-induced protection.
Topics: 2,4-Dinitrophenol; Adenosine; Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-Agonists; Anima | 2004 |
Metabolic flexibility permits mesenchymal stem cell survival in an ischemic environment.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Cell Differentiation; Cell Hypoxia; Cell Surviva | 2008 |
[Comparative study on pharmacological effects of various species of Pueraria].
Topics: 2,4-Dinitrophenol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinitrophenols; Drugs, Chinese | 1995 |
The effects of low-flow ischemia on K+ fluxes in isolated rat hearts assessed by 87Rb NMR.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Coronary Circulation; Energy Metabolism; Hemodyn | 1999 |
Blockade of adenosine triphosphate-sensitive potassium channels by thiamylal in rat ventricular myocytes.
Topics: 2,4-Dinitrophenol; Anesthetics, Intravenous; Animals; ATP-Binding Cassette Transporters; Cell Separa | 2000 |
Mechanism of the increase in intracellular sodium during metabolic inhibition: direct evidence against mediation by voltage-dependent sodium channels.
Topics: 2,4-Dinitrophenol; Animals; Antimetabolites; Calcium; Dinitrophenols; Electric Conductivity; Guinea | 1992 |