2,4-dinitrophenol has been researched along with Cancer of Colon in 6 studies
2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A subline of human colon carcinoma cells (WiDr/R) resistant to the cytotoxic effects of mitoxantrone in vitro, was developed by continuous exposure to increasing concentrations of drug." | 7.67 | Development of resistance and characteristics of a human colon carcinoma subline resistant to mitoxantrone in vitro. ( Durr, FE; Lindh, D; Wallace, RE, 1987) |
| "The formation of the glutathione S-conjugate of monochlorobimane (GSH-bimane) in human colon adenocarcinoma cells was identified by HPLC-fluorimetry and its transport from the cells was found to be temperature-sensitive, saturable and ATP-dependent." | 3.69 | Active transport of glutathione S-conjugate in human colon adenocarcinoma cells. ( Wong, KP; Zhang, K, 1996) |
| "A subline of human colon carcinoma cells (WiDr/R) resistant to the cytotoxic effects of mitoxantrone in vitro, was developed by continuous exposure to increasing concentrations of drug." | 3.67 | Development of resistance and characteristics of a human colon carcinoma subline resistant to mitoxantrone in vitro. ( Durr, FE; Lindh, D; Wallace, RE, 1987) |
| " The analogs 2a and 2b have submicromolar IC(50) values towards human HCT-116 colon cancer cells but are far less toxic to human non-malignant CRL-1790 colon cells." | 1.39 | Mitochondrial dysfunction contributes to the cytotoxicity of some 3,5-bis(benzylidene)-4-piperidone derivatives in colon HCT-116 cells. ( Bandy, B; Das, U; Dimmock, JR; Helal, M; Islam, A; Nazarali, AJ, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Helal, M | 1 |
| Das, U | 2 |
| Bandy, B | 2 |
| Islam, A | 1 |
| Nazarali, AJ | 1 |
| Dimmock, JR | 2 |
| Addala, E | 1 |
| Rafiei, H | 1 |
| Das, S | 1 |
| Karki, SS | 1 |
| Gan, LS | 1 |
| Niederer, T | 1 |
| Eads, C | 1 |
| Thakker, D | 1 |
| Zhang, K | 1 |
| Wong, KP | 1 |
| Wallace, RE | 1 |
| Lindh, D | 1 |
| Durr, FE | 1 |
| Mückter, H | 1 |
| Ben-Shaul, Y | 1 |
| Bacher, A | 1 |
6 other studies available for 2,4-dinitrophenol and Cancer of Colon
| Article | Year |
|---|---|
Mitochondrial dysfunction contributes to the cytotoxicity of some 3,5-bis(benzylidene)-4-piperidone derivatives in colon HCT-116 cells.
Topics: Animals; Colonic Neoplasms; Glutathione; HCT116 Cells; Humans; Membrane Potential, Mitochondrial; Mi | 2013 |
3,5-Bis(3-dimethylaminomethyl-4-hydroxybenzylidene)-4-piperidone and related compounds induce glutathione oxidation and mitochondria-mediated cell death in HCT-116 colon cancer cells.
Topics: Apoptosis; Cell Line; Colonic Neoplasms; Curcumin; Glutathione; HCT116 Cells; Humans; Membrane Poten | 2017 |
Evidence for predominantly paracellular transport of thyrotropin-releasing hormone across CACO-2 cell monolayers.
Topics: 2,4-Dinitrophenol; Adenocarcinoma; Amiloride; Azides; Biological Transport; Cell Line; Cell Membrane | 1993 |
Active transport of glutathione S-conjugate in human colon adenocarcinoma cells.
Topics: 2,4-Dinitrophenol; Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Agents; Biological Transpo | 1996 |
Development of resistance and characteristics of a human colon carcinoma subline resistant to mitoxantrone in vitro.
Topics: 2,4-Dinitrophenol; Carcinoma; Cell Nucleus; Colonic Neoplasms; Dinitrophenols; DNA, Neoplasm; Drug R | 1987 |
ATP requirement for induced tight junction formation in HT 29 adenocarcinoma cells.
Topics: 2,4-Dinitrophenol; Adenocarcinoma; Adenosine Triphosphate; Cell Membrane; Colonic Neoplasms; Deoxygl | 1987 |