2,4-dinitrophenol has been researched along with Alzheimer Disease in 4 studies
2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.
Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Excerpt | Relevance | Reference |
|---|---|---|
| "One of the earliest manifestations of Alzheimer's disease (AD) is the characteristic inability of affected individuals to form new memories." | 2.44 | Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer's disease. ( Barbosa, AC; De Felice, FG; Ferreira, ST; Gomes, FC; Klein, WL; Wasilewska-Sampaio, AP, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paula Lima, AC | 1 |
| Arriagada, C | 1 |
| Toro, R | 1 |
| Cárdenas, AM | 1 |
| Caviedes, R | 1 |
| Ferreira, ST | 3 |
| Caviedes, P | 1 |
| Choi, J | 1 |
| Sullards, MC | 1 |
| Olzmann, JA | 1 |
| Rees, HD | 1 |
| Weintraub, ST | 1 |
| Bostwick, DE | 1 |
| Gearing, M | 1 |
| Levey, AI | 1 |
| Chin, LS | 1 |
| Li, L | 1 |
| De Felice, FG | 2 |
| Wasilewska-Sampaio, AP | 1 |
| Barbosa, AC | 1 |
| Gomes, FC | 1 |
| Klein, WL | 1 |
2 reviews available for 2,4-dinitrophenol and Alzheimer Disease
| Article | Year |
|---|---|
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus.
Topics: 2,4-Dinitrophenol; Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Humans; Mitochondria; | 2006 |
Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer's disease.
Topics: 2,4-Dinitrophenol; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; A | 2007 |
2 other studies available for 2,4-dinitrophenol and Alzheimer Disease
| Article | Year |
|---|---|
Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line.
Topics: 2,4-Dinitrophenol; Alzheimer Disease; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Ce | 2008 |
Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases.
Topics: 2,4-Dinitrophenol; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Blotting, Wester | 2006 |