2,4-dinitrophenol has been researched along with Acute Liver Injury, Drug-Induced in 6 studies
2,4-Dinitrophenol: A toxic dye, chemically related to trinitrophenol (picric acid), used in biochemical studies of oxidative processes where it uncouples oxidative phosphorylation. It is also used as a metabolic stimulant. (Stedman, 26th ed)
dinitrophenol : Members of the class of nitrophenol carrying two nitro substituents.
2,4-dinitrophenol : A dinitrophenol having the nitro groups at the 2- and 4-positions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dinoseb is a highly toxic pesticide of the dinitrophenol group." | 1.46 | Distribution, lipid-bilayer affinity and kinetics of the metabolic effects of dinoseb in the liver. ( Bracht, A; Bracht, F; Bracht, L; de Sá-Nakanishi, AB; Parizotto, AV; Peralta, RM; Salla, GBF, 2017) |
| " An understanding of structure-activity relationships (SARs) of chemicals can make a significant contribution to the identification of potential toxic effects early in the drug development process and aid in avoiding such problems." | 1.36 | Developing structure-activity relationships for the prediction of hepatotoxicity. ( Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greene, N | 1 |
| Fisk, L | 1 |
| Naven, RT | 1 |
| Note, RR | 1 |
| Patel, ML | 1 |
| Pelletier, DJ | 1 |
| Ekins, S | 1 |
| Williams, AJ | 1 |
| Xu, JJ | 1 |
| Salla, GBF | 1 |
| Bracht, L | 1 |
| de Sá-Nakanishi, AB | 1 |
| Parizotto, AV | 1 |
| Bracht, F | 1 |
| Peralta, RM | 1 |
| Bracht, A | 1 |
| Izumoto, S | 1 |
| Taniguchi, A | 1 |
| Mochizuki, H | 1 |
| Shiomi, K | 1 |
| Nakazato, M | 1 |
| George, M | 1 |
| Chenery, RJ | 1 |
| Krishna, G | 1 |
| Strubelt, O | 1 |
6 other studies available for 2,4-dinitrophenol and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Distribution, lipid-bilayer affinity and kinetics of the metabolic effects of dinoseb in the liver.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Biological Transport; Chemical and Drug Induced | 2017 |
Sensory axonal polyneuropathy due to 2,4-dinitrophenol.
Topics: 2,4-Dinitrophenol; Adult; Anti-Obesity Agents; Chemical and Drug Induced Liver Injury; Humans; Illic | 2017 |
The effect of ionophore A23187 and 2,4-dinitrophenol on the structure and function of cultured liver cells.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Calcimycin; Cells, Cultur | 1982 |
Influence of 2,4-dinitrophenol on the susceptibility of rats to hepatotoxic injury.
Topics: 2,4-Dinitrophenol; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1981 |