Compounds > 2-4-dinitrofluorobenzene-sulfonic-acid

2-4-dinitrofluorobenzene-sulfonic-acid and Burns

2-4-dinitrofluorobenzene-sulfonic-acid has been researched along with Burns* in 1 studies

Other Studies

1 other study(ies) available for 2-4-dinitrofluorobenzene-sulfonic-acid and Burns

Article	Year
The effect of histamine receptor antagonists on specific and nonspecific suppression of experimental contact sensitivity. The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:1 We studied the effects of H1 and H2 histamine receptor antagonists on down regulation of contact sensitivity (CS) to dinitrofluorobenzene (DNFB). Two H2 receptor antagonists, cimetidine and ranitidine, reversed the nonspecific immunosuppression of CS induced by burns. On the other hand, these two drugs did not affect the antigen-specific suppressor T cell-mediated tolerance to DNFB induced by dinitrobenzene sulfonic acid. Two H1 antagonists did not affect the down regulation of CS induced by either tolerance or burning. The differential sensitivities to histamine 2-receptor antagonists indicate that the mechanisms for nonspecific burn-induced immunosuppression are different from those for hapten-specific tolerance to DNFB. Topics: Animals; Burns; Cimetidine; Dermatitis, Contact; Dinitrofluorobenzene; Female; Histamine Antagonists; Immune Tolerance; Mice; Mice, Inbred BALB C; Ranitidine; T-Lymphocytes, Regulatory	1985

Article

Year

The effect of histamine receptor antagonists on specific and nonspecific suppression of experimental contact sensitivity.

The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:1

We studied the effects of H1 and H2 histamine receptor antagonists on down regulation of contact sensitivity (CS) to dinitrofluorobenzene (DNFB). Two H2 receptor antagonists, cimetidine and ranitidine, reversed the nonspecific immunosuppression of CS induced by burns. On the other hand, these two drugs did not affect the antigen-specific suppressor T cell-mediated tolerance to DNFB induced by dinitrobenzene sulfonic acid. Two H1 antagonists did not affect the down regulation of CS induced by either tolerance or burning. The differential sensitivities to histamine 2-receptor antagonists indicate that the mechanisms for nonspecific burn-induced immunosuppression are different from those for hapten-specific tolerance to DNFB.

Topics: Animals; Burns; Cimetidine; Dermatitis, Contact; Dinitrofluorobenzene; Female; Histamine Antagonists; Immune Tolerance; Mice; Mice, Inbred BALB C; Ranitidine; T-Lymphocytes, Regulatory

1985