2,4-dichlorophenoxyacetic acid has been researched along with Myotonia in 24 studies
2,4-Dichlorophenoxyacetic Acid: An herbicide with irritant effects on the eye and the gastrointestinal system.
2,4-D : A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.
Myotonia: Prolonged failure of muscle relaxation after contraction. This may occur after voluntary contractions, muscle percussion, or electrical stimulation of the muscle. Myotonia is a characteristic feature of MYOTONIC DISORDERS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "English Pointer dogs dosed po with encapsulated 2,4-dichlorophenoxyacetic acid (2,4-D) or 2-methoxy-3,6-dichlorobenzoic acid (dicamba) developed varying degrees of myotonia." | 7.68 | 2,4-D toxicosis. I: A pilot study of 2,4-dichlorophenoxyacetic acid- and dicamba-induced myotonia in experimental dogs. ( Arnold, EK; Beasley, VR; Lovell, RA; Parker, AJ, 1991) |
| "Myotonia is characterized by prolonged contraction (delay in onset of relaxation) of skeletal muscle fibers with characteristic electromyographic findings." | 5.28 | Effect of diltiazem on 2,4-D-induced myotonia in rats. ( al-Rajeh, S; Iyer, V; Olson, WH, 1989) |
| "The relation between resistance to fatigue and intramuscular pH was studied in fast muscles (anterior tibialis and extensor digitorum longus) from rats treated with 2,4-dichlorophenoxyacetic acid (2,4-D) to induce myotonia." | 3.67 | Intramuscular pH and endurance are abnormal in skeletal muscles from rats with experimental myotonia. ( Ramírez, BU; Soza, MA, 1988) |
| "Myotonia is characterized by prolonged contraction (delay in onset of relaxation) of skeletal muscle fibers with characteristic electromyographic findings." | 1.28 | Effect of diltiazem on 2,4-D-induced myotonia in rats. ( al-Rajeh, S; Iyer, V; Olson, WH, 1989) |
| "Quinine was not used because of the well known side-effects." | 1.26 | [The influence of several membrane stabilizing drugs on the induced hereditary myotonia--a methodic way to test the effectiveness of drugs on myotonia (author's transl)]. ( Wagner, A; Zett, L, 1981) |
| "While myotonia is the result of a primary defect in the muscle membrane, these experiments indicate the innervation is necessary to maintain the muscle membrane in a state that will support myotonia." | 1.26 | Neural influence on experimental myotonia. ( Fenichel, G; Iyer, V; Whiting, M, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (87.50) | 18.7374 |
| 1990's | 2 (8.33) | 18.2507 |
| 2000's | 1 (4.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wagner, A | 2 |
| Zett, L | 2 |
| Iyer, VG | 1 |
| Ranish, NA | 3 |
| Fenichel, GM | 2 |
| McArdle, JJ | 1 |
| Guarino, C | 1 |
| D'Alonzo, AJ | 1 |
| Dickow, LM | 1 |
| Podell, M | 1 |
| Gerken, DF | 1 |
| Laskowski, MB | 1 |
| Dettbarn, WD | 2 |
| Kuhn, E | 2 |
| Fiehn, W | 1 |
| Rüdel, R | 3 |
| Schröder, JM | 1 |
| Seiler, D | 2 |
| Mazareán, HH | 2 |
| Dux, L | 2 |
| Guba, F | 2 |
| Iyer, V | 5 |
| Whiting, M | 1 |
| Fenichel, G | 1 |
| Beasley, VR | 1 |
| Arnold, EK | 1 |
| Lovell, RA | 1 |
| Parker, AJ | 1 |
| Ramírez, BU | 2 |
| Al-Sulaiman, A | 1 |
| Al-Rajeh, S | 2 |
| Olson, WH | 1 |
| Soza, MA | 1 |
| Brody, IA | 1 |
| Graff, GL | 2 |
| Gueuning, C | 2 |
| Vanderkelen, B | 2 |
| Senges, J | 2 |
2 reviews available for 2,4-dichlorophenoxyacetic acid and Myotonia
| Article | Year |
|---|---|
The pharmacology of experimental myopathies.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anura; Biogenic Amines; Cholesterol; Cholinesterase Inhibit | 1977 |
[Myotonia].
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Cell Membrane Permeability; Chlorides; Cholesterol; Disease | 1976 |
22 other studies available for 2,4-dichlorophenoxyacetic acid and Myotonia
| Article | Year |
|---|---|
[The influence of several membrane stabilizing drugs on the induced hereditary myotonia--a methodic way to test the effectiveness of drugs on myotonia (author's transl)].
Topics: 2,4-Dichlorophenoxyacetic Acid; Adolescent; Adult; Ajmaline; Animals; Child; Electrolytes; Electromy | 1981 |
[Modification of 2,4-dichlorophenoxyacetate-induced myotonia of cold blood muscles by variations in external Ca++ and K+ concentrations].
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Calcium; Cations; Electromyography; Membrane Potentials; Mu | 1983 |
Ionic conductance and experimentally induced myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Diaphragm; Muscle Contraction; Myotonia; Potassium; Rats | 1981 |
Neuronal influences on the sensitivity of skeletal muscle to experimental myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Colchicine; Evoked Potentials; Male; Muscle Contraction; Mu | 1980 |
Clinical effects and plasma concentration determination after 2,4-dichlorophenoxyacetic acid 200 mg/kg administration in the dog.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Chromatography, High Pressure Liquid; Diarrhea; Dogs; Elect | 2000 |
[Hereditary and experimental myotonia: a comparative study (author's transl)].
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenosine Triphosphatases; Animals; Erythrocyte Membrane; Erythrocyt | 1979 |
Changes of metabolism during experimentally induced myotonia of rats. I. Alterations in lactate and malate dehydrogenase isoenzyme activities.
Topics: 2,4-Dichlorophenoxyacetic Acid; Anaerobiosis; Animals; Isoenzymes; L-Lactate Dehydrogenase; Malate D | 1979 |
Changes of metabolism during experimentally induced myotonia of rats. II. Alterations in creatine kinase and acid phosphatase activities: a possible mechanism in the development of muscle damage.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acid Phosphatase; Animals; Creatine Kinase; Energy Metabolism; Glyco | 1979 |
Neural influence on experimental myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Male; Muscles; Myotonia; Myotonia Congenita; Nervous System | 1977 |
The effect of denervation on subsequent in vitro induction of myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Chlorides; Diaphragm; Evoked Potentials; In Vitro Technique | 1977 |
The influence of nerve stump length on (2,4-dichlorophenoxy)acetic acid-induced myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Electromyography; Muscle Denervation; Muscles; Myotonia; Ra | 1977 |
2,4-D toxicosis. I: A pilot study of 2,4-dichlorophenoxyacetic acid- and dicamba-induced myotonia in experimental dogs.
Topics: 2,4-Dichlorophenoxyacetic Acid; Administration, Oral; Animals; Dicamba; Dogs; Dose-Response Relation | 1991 |
Energetic metabolism and fatigability in experimental myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Disease Models, Animal; Electromyography; Energy Metabolism | 1990 |
The influence of skeletal muscle reinnervation on experimentally induced myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Axonal Transport; Cell Membrane Permeability; Disease Model | 1986 |
Effect of diltiazem on 2,4-D-induced myotonia in rats.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Diltiazem; In Vitro Techniques; Muscle Contraction; Myotoni | 1989 |
Intramuscular pH and endurance are abnormal in skeletal muscles from rats with experimental myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Action Potentials; Animals; Electromyography; Hydrogen-Ion Concentra | 1988 |
The ATPases of the sarcolemma from skeletal muscle in experimental myotonia.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenosine Triphosphatases; Androstanes; Animals; Cholesterol; Electr | 1971 |
Myotonia induced by monocarboxylic aromatic acids. A possible mechanism.
Topics: 2,4-Dichlorophenoxyacetic Acid; Adenosine Triphosphatases; Animals; Benzoates; Carboxylic Acids; Cel | 1973 |
[Influence of 2,4-dichlorophenoxyacetic (2-4D) acid, a myotonizing agent, on acidosoluble phosphate metabolism in rat skeletal muscle].
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Depression, Chemical; Herbicides; Muscles; Myotonia; Phosph | 1972 |
[Influence of 2,4-dichlorophenoxyacetic (2-rD) acid, a myotonizing agent, on acidosoluble phosphate metabolism in rat skeletal muscle].
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Depression, Chemical; Herbicides; Muscles; Myotonia; Phosph | 1973 |
Experimental myotonia in mammalian skeletal muscle: changes in contractile properties.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acetates; Animals; Diaphragm; Electromyography; In Vitro Techniques; | 1972 |
Experimental myotonia in mammalian skeletal muscle: changes in membrane properties.
Topics: 2,4-Dichlorophenoxyacetic Acid; Acetates; Action Potentials; Animals; Diaphragm; Membrane Potentials | 1972 |