2,4-dichlorophenoxyacetic acid has been researched along with Fetal Death in 13 studies
2,4-Dichlorophenoxyacetic Acid: An herbicide with irritant effects on the eye and the gastrointestinal system.
2,4-D : A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.
Fetal Death: Death of the developing young in utero. BIRTH of a dead FETUS is STILLBIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of herbicide--2,4-D, injected before pregnancy begins, on the main parameters of the reproductive function of the female rats has demonstrated that chronic administration in doses 1 mg/kg and 12 mg/kg per day for 2 months results in certain disturbances in the estrus cycle, manifesting as prolongation of the diestrus phase and in changes of estrus and meta-estrus++ duration, as well as in an essential increase in rates of anovulatory cycles." | 5.28 | [Nature of the estrous cycle, incidence of anovulation, chromosome gametopathies and fetal death in female rats with 2,4-dichlorophenoxyacetic acid (2,4-D) before pregnancy]. ( Nikitin, AI; Slozina, NM; Vin', VD, 1990) |
| "From the group of herbicidal phenoxy carbonic acids, 2-methyl-4-chlorophenoxyacetic acid (MCPA; 0-500 mg/kg), 2-(4-chloro-2-methyl-phenoxy) propionic acid (mecoprop/MCPP; 0-700 mg/kg) and 2-(2,4-dichlorophenoxy) propionic acid (dichlorprop/2,4-DP; 0-500 mg/kg) as well as the dextrorotatory compounds of MCPP (MCPPD; 0-500 mg/kg) and 2,4-DP (2,4-DPD; 0-500 mg/kg) were studied in NMRI mice after oral administration between days 6-15 of pregnancy." | 3.66 | [Comparative studies on the embryotoxicity of 2-methyl-4-chlorophenoxyacetic acid, mecoprop and dichlorprop in NMRI mice]. ( Matthiaschk, G; Roll, R, 1983) |
| " The data, although apparently influenced by season, showed an inverted or U-shaped dose-response pattern for reduced litter size, with the low end of the dose range producing the greatest decrease in the number of live pups born." | 1.31 | Developmental toxicity of a commercial herbicide mixture in mice: I. Effects on embryo implantation and litter size. ( Cavieres, MF; Jaeger, J; Porter, W, 2002) |
| "The risk of intrauterine growth retardation was not increased in any exposure category." | 1.30 | Paternal dioxin, preterm birth, intrauterine growth retardation, and infant death. ( Boyle, CA; Michalek, JE; Rahe, AJ, 1998) |
| "The hypothesis that chemically induced overt maternal toxicity induces a characteristic syndrome of adverse developmental effects in the rat was investigated." | 1.28 | Effects of chemically induced maternal toxicity on prenatal development in the rat. ( Chernoff, N; Miller, DB; Rogers, JM; Rosen, MB; Setzer, RW, 1990) |
| "The effect of herbicide--2,4-D, injected before pregnancy begins, on the main parameters of the reproductive function of the female rats has demonstrated that chronic administration in doses 1 mg/kg and 12 mg/kg per day for 2 months results in certain disturbances in the estrus cycle, manifesting as prolongation of the diestrus phase and in changes of estrus and meta-estrus++ duration, as well as in an essential increase in rates of anovulatory cycles." | 1.28 | [Nature of the estrous cycle, incidence of anovulation, chromosome gametopathies and fetal death in female rats with 2,4-dichlorophenoxyacetic acid (2,4-D) before pregnancy]. ( Nikitin, AI; Slozina, NM; Vin', VD, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cavieres, MF | 1 |
| Jaeger, J | 1 |
| Porter, W | 1 |
| Boulakoud, MS | 1 |
| Mosbah, R | 1 |
| Abdennour, C | 1 |
| Khelili, K | 1 |
| Roll, R | 1 |
| Matthiaschk, G | 1 |
| Michalek, JE | 1 |
| Rahe, AJ | 1 |
| Boyle, CA | 1 |
| Aleksashina, ZA | 1 |
| Buslovich, SIu | 1 |
| Kolosovskaia, VM | 1 |
| Courtney, KD | 1 |
| Chernoff, N | 1 |
| Setzer, RW | 1 |
| Miller, DB | 1 |
| Rosen, MB | 1 |
| Rogers, JM | 1 |
| Vin', VD | 1 |
| Slozina, NM | 1 |
| Nikitin, AI | 1 |
| Bidnenko, LI | 1 |
| Konstantinova, TK | 2 |
| Shevelo, FS | 1 |
| Antonenko, TA | 1 |
| Ermolov, VI | 1 |
| Båge, G | 1 |
| Cekanova, E | 1 |
| Larsson, KS | 1 |
| Khera, KS | 1 |
| McKinley, WP | 1 |
13 other studies available for 2,4-dichlorophenoxyacetic acid and Fetal Death
| Article | Year |
|---|---|
Developmental toxicity of a commercial herbicide mixture in mice: I. Effects on embryo implantation and litter size.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Animals; Animals, Newborn; Birt | 2002 |
The toxicological effects of the herbicide 2,4-DCPA on progesterone levels and mortality in Wistar female rats.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Dose-Response Relationship, Drug; Female; Fertility; Fetal | 2001 |
[Comparative studies on the embryotoxicity of 2-methyl-4-chlorophenoxyacetic acid, mecoprop and dichlorprop in NMRI mice].
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Animals; Drug Interactions; Emb | 1983 |
Paternal dioxin, preterm birth, intrauterine growth retardation, and infant death.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Adolescent; Adult; Agent Orange; | 1998 |
[Characteristics of the embryotoxic action of herbicides, derivatives of 2,4-dichlorophenoxyacetic acid].
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Embryo Loss; Embryo, Mammalian; Female; Fetal Death; Herbic | 1979 |
Prenatal effects of herbicides: evaluation by the prenatal development index.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Cleft Palat | 1977 |
Effects of chemically induced maternal toxicity on prenatal development in the rat.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Cacodylic A | 1990 |
[Nature of the estrous cycle, incidence of anovulation, chromosome gametopathies and fetal death in female rats with 2,4-dichlorophenoxyacetic acid (2,4-D) before pregnancy].
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anovulation; Chromosome Aberrations; Estrus; Female; Fetal | 1990 |
[Various aspects of the hygiene and toxicology of the herbicide sangor].
Topics: 2,4-Dichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Food Cont | 1986 |
[The degree of toxicity of the combined effects of chlorophenoxy derivative herbicides on reproductive function of warm-blooded animals, and the problems of their hygienic regulation].
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Anim | 1986 |
[Mechanism of the embryotropic action of 2,4-dichlorophenoxyacetic acid].
Topics: 2,4-Dichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Animals, Newborn; Dose-Respons | 1985 |
Teratogenic and embryotoxic of the herbicides di- and trichlorophenoxyacetic acids (2,4-D and 2,4,5-T).
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Anim | 1973 |
Pre- and postnatal studies on 2,4,5-trichlorophenoxyacetic acid, 2,4-dichlorophenoxyacetic acid and their derivatives in rats.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acet | 1972 |