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2,4-dichlorophenoxyacetic acid and Body Weight

2,4-dichlorophenoxyacetic acid has been researched along with Body Weight in 41 studies

2,4-Dichlorophenoxyacetic Acid: An herbicide with irritant effects on the eye and the gastrointestinal system.
2,4-D : A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2 and 4 are substituted by chlorines.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Channel catfish (Ictalurus punctatus) exposed to a mixture of picloram and 2,4-dichlorophenoxyacetic acid (2,4-D) for 10 days displayed increased activities of hepatic ethoxyresorufin O-deethylase (EROD), decreased serum chloride concentrations and decreased liver/body weight ratios."3.68Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus). ( Di Giulio, RT; Gallagher, EP, 1991)
" The 2, 4-D-treated group received a single oral gavage LD50 dose of 639 mg/kg body weight; the rats were then killed and the livers excised 24 h after 2, 4-D administration."1.43Evaluation of the toxic effect of the herbicide 2, 4-D on rat hepatocytes: an FT-IR spectroscopic study. ( Dakhakhni, TH; Qusti, SY; Raouf, GA, 2016)
" The "No Observed Adverse Effect Level" for systemic toxicity was 300 ppm in both males (16."1.39An F1-extended one-generation reproductive toxicity study in Crl:CD(SD) rats with 2,4-dichlorophenoxyacetic acid. ( Andrus, AK; Boverhof, DR; Bus, JS; Hammond, L; Lamb, JC; Lawson, MA; Marty, MS; Neal, BH; Passage, JK; Perala, AW; Saghir, SA; Woolhiser, MR; Yano, BL; Zablotny, CL, 2013)
" In this study we analyzed the toxic effects of 2,4-D on rat liver."1.36Hepatotoxicity induced by sub-acute exposure of rats to 2,4-Dichlorophenoxyacetic acid based herbicide "Désormone lourd". ( Attia, N; Hammami, M; Miled, A; Nakbi, A; Tayeb, W; Trabelsi, M, 2010)
" Significantly decreased fetal body weights and increased fetal variations were seen in rats only at maternally toxic dose levels in excess of 90 mg/kg/day acid equivalent."1.31Developmental toxicity studies in rats and rabbits on 2,4-dichlorophenoxyacetic acid and its forms. ( Bus, JS; Charles, JM; Hanley, TR; van Ravenzwaay, B; Wilson, RD, 2001)
" Negative controls were males dosed with distilled water, and positive controls were males dosed with cyclophosphamide at 5."1.31A study of the potential for a herbicide formulation containing 2,4-d and picloram to cause male-mediated developmental toxicity in rats. ( Brown-Woodman, PD; Oakes, DJ; Ritchie, HE; Webster, WS, 2002)
" The data from the three subchronic studies demonstrated the comparable toxicity of ACID, DMA, and 2-EHE and support a subchronic no observed adverse effect level (NOAEL) of 1."1.29Comparative subchronic and chronic dietary toxicity studies on 2,4-dichlorophenoxyacetic acid, amine, and ester in the dog. ( Bus, JS; Charles, JM; Cunny, HC; Dalgard, DW; Wilson, RD, 1996)
"The hypothesis that chemically induced overt maternal toxicity induces a characteristic syndrome of adverse developmental effects in the rat was investigated."1.28Effects of chemically induced maternal toxicity on prenatal development in the rat. ( Chernoff, N; Miller, DB; Rogers, JM; Rosen, MB; Setzer, RW, 1990)
"The acute oral LD50 of 2,4-dichlorophenol (2,4-DCP) employing corn oil as vehicle was determined to be 1352 mg/kg for female and 1276 mg/kg for male CD-1 mice."1.27Acute and subchronic toxicity of 2,4-dichlorophenol in CD-1 mice. ( Borzelleca, JF; Condie, LW; Egle, JL; Hayes, JR, 1985)

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199013 (31.71)18.7374
1990's10 (24.39)18.2507
2000's8 (19.51)29.6817
2010's7 (17.07)24.3611
2020's3 (7.32)2.80

Authors

AuthorsStudies
Rocha, VA1
Aquino, AM1
Magosso, N1
Souza, PV1
Justulin, LA1
Domeniconi, RF1
Barbisan, LF1
Romualdo, GR1
Scarano, WR1
Shafeeq, S1
Mahboob, T1
Trea, F1
Tichati, L1
Ouali, K1
Marty, MS2
Neal, BH2
Zablotny, CL2
Yano, BL2
Andrus, AK1
Woolhiser, MR1
Boverhof, DR1
Saghir, SA2
Perala, AW2
Passage, JK2
Lawson, MA1
Bus, JS6
Lamb, JC1
Hammond, L2
Dakhakhni, TH1
Raouf, GA1
Qusti, SY1
Yeşilkaya, E1
Bideci, A1
Ozer, C1
Elmas, C1
Camurdan, O1
Giray, SG1
Boyraz, M1
Vurucu, S1
Cinaz, P1
Stürtz, N2
Jahn, GA1
Deis, RP1
Rettori, V1
Duffard, RO1
Evangelista de Duffard, AM2
Tayeb, W1
Nakbi, A1
Trabelsi, M1
Attia, N1
Miled, A1
Hammami, M1
Correia, FV1
Moreira, JC1
Mazhar, FM1
Moawad, KM1
El-Dakdoky, MH1
Amer, AS1
Bongiovanni, B1
Rassetto, M1
Ferri, A1
de Duffard, AM3
Duffard, R4
Konjuh, C1
García, G1
López, L1
Brusco, A1
Bogdan, AS1
de Moro, GM1
Speranskiĭ, VV1
Speranskaia, TN1
Zhamsaranova, SD1
Gonchikova, TsD1
Charles, JM4
Dalgard, DW1
Cunny, HC3
Wilson, RD4
Rosso, SB1
Di Paolo, OA1
Mattsson, JL2
Blakley, BR2
Yole, MJ1
Brousseau, P1
Boermans, H1
Fournier, M1
Mikov, I1
Milosevic, M1
Mikov, A1
Mikov, M1
Hanley, TR1
van Ravenzwaay, B1
Lee, K1
Johnson, VL1
Oakes, DJ1
Webster, WS1
Brown-Woodman, PD1
Ritchie, HE1
Fofana, D1
Kobae, H1
Sameshima, K1
Miyata, K1
Somers, JD1
Moran, ET2
Reinhart, BS2
Courtney, KD1
Tamburro, CH1
Gallagher, EP1
Di Giulio, RT1
Chernoff, N1
Setzer, RW1
Miller, DB1
Rosen, MB1
Rogers, JM1
Kuntz, DJ1
Rao, NG1
Berg, IE1
Khattree, R1
Chaturvedi, AK1
Ohta, F1
Gaudemer, F1
Lutton, C1
Gorzinski, SJ1
Kociba, RJ1
Campbell, RA1
Smith, FA1
Nolan, RJ1
Eisenbrandt, DL1
Johnson, KA1
Albee, RR1
Borzelleca, JF1
Hayes, JR1
Condie, LW1
Egle, JL1
Somers, J1
Whitehead, CC1
Pettigrew, RJ1
Khera, KS1
McKinley, WP1
Erne, K1
Björklund, NE1
Hansen, WH1
Quaife, ML1
Habermann, RT1
Fitzhugh, OG1

Other Studies

41 other studies available for 2,4-dichlorophenoxyacetic acid and Body Weight

ArticleYear
2,4-dichlorophenoxyacetic acid (2,4-D) exposure during postnatal development alters the effects of western diet on mouse prostate.
    Reproductive toxicology (Elmsford, N.Y.), 2023, Volume: 120

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Diet, Western; Herbicides; Male; Mice; Mice, I

2023
Magnesium supplementation ameliorates toxic effects of 2,4-dichlorophenoxyacetic acid in rat model.
    Human & experimental toxicology, 2020, Volume: 39, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Antioxidants; Biomarkers; Body Weight; Gene Expression Regu

2020
Protective effect of
    Drug and chemical toxicology, 2022, Volume: 45, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Antioxidants; Body Weight; Glutathione; Glutathione Peroxid

2022
An F1-extended one-generation reproductive toxicity study in Crl:CD(SD) rats with 2,4-dichlorophenoxyacetic acid.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:2

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Dose-Response Relationship, Drug; Endocrine Gl

2013
Life-stage-, sex-, and dose-dependent dietary toxicokinetics and relationship to toxicity of 2,4-dichlorophenoxyacetic acid (2,4-D) in rats: implications for toxicity test dose selection, design, and interpretation.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:2

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Area Under Curve; Body Weight; Diet; Dose-Response Relation

2013
Evaluation of the toxic effect of the herbicide 2, 4-D on rat hepatocytes: an FT-IR spectroscopic study.
    European biophysics journal : EBJ, 2016, Volume: 45, Issue:4

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Hepatocytes; Herbicides; Lipid Metabolism; Mal

2016
Plant growth regulator (4-chlorophenoxy acetic acid) increases apoptosis in gonads of rats without changing hormonal levels.
    Hormone research, 2009, Volume: 72, Issue:4

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Apoptosis; Body Weight; Dose-Response Relationship, Drug; E

2009
Effect of 2,4-dichlorophenoxyacetic acid on milk transfer to the litter and prolactin release in lactating rats.
    Toxicology, 2010, Apr-30, Volume: 271, Issue:1-2

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Animals, Suckling; Biogenic Monoamines; Body Weight; Brain;

2010
Hepatotoxicity induced by sub-acute exposure of rats to 2,4-Dichlorophenoxyacetic acid based herbicide "Désormone lourd".
    Journal of hazardous materials, 2010, Aug-15, Volume: 180, Issue:1-3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Catalase; Drinking Behavior; Feeding Behavior;

2010
Effects of glyphosate and 2,4-D on earthworms (Eisenia foetida) in laboratory tests.
    Bulletin of environmental contamination and toxicology, 2010, Volume: 85, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Glycine; Glyphosate; Growth and Development; H

2010
Fetotoxicity of 2,4-dichlorophenoxyacetic acid in rats and the protective role of vitamin E.
    Toxicology and industrial health, 2014, Volume: 30, Issue:5

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Bone and Bones; Female; Fetus; Male; Oxidative

2014
Detection of 2,4-dichlorophenoxyacetic acid in rat milk of dams exposed during lactation and milk analysis of their major components.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Animals, Newborn; Animals, Suckling; Body Weight; Eating; F

2006
Neonatal hypomyelination by the herbicide 2,4-dichlorophenoxyacetic acid. Chemical and ultrastructural studies in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 104, Issue:2

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Animals, Suckling; Blotting, Western; Body Weight; Brain; D

2008
[Effect of chlorine derivative of phenoxy acid herbicides on the biological value of the grain from cereal crops].
    Voprosy pitaniia, 1983, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Chlorobenzoates; Edible Grain; Herbicides; Nut

1983
Hatching and lipid composition of chicks brain from eggs treated with 2,4-dichlorophenoxyacetic butyl ester.
    Toxicology, 1982, Volume: 24, Issue:3-4

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Brain; Brain Chemistry; Chick Embryo; Choleste

1982
[Biologic activity and toxicologic effect of 2,4-D bounded forms].
    Gigiena i sanitariia, 1994, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Albumins; Animals; Body Weight; Caseins; Chromatography, High Pressu

1994
Comparative subchronic and chronic dietary toxicity studies on 2,4-dichlorophenoxyacetic acid, amine, and ester in the dog.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 29, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Administration, Oral; Animals; Body Weight; Chemistry, Clinical; Dog

1996
Comparative subchronic studies on 2,4-dichlorophenoxyacetic acid, amine, and ester in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1996, Volume: 33, Issue:2

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Blood Cells; Body Weight; Dimethylamines; Esters; Feeding B

1996
Effects of 2,4-dichlorophenoxyacetic acid on central nervous system of developmental rats. Associated changes in ganglioside pattern.
    Brain research, 1997, Sep-19, Volume: 769, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Aging; Animals; Body Weight; Brain; Central Nervous System; Female;

1997
Single-dose and chronic dietary neurotoxicity screening studies on 2,4-dichlorophenoxyacetic acid in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 40, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Behavior, Animal; Body Weight; Diet; Female; Hand Strength;

1997
Effect of 2,4-dicholorophenoxyacetic acid, trifluralin and triallate herbicides on immune function.
    Veterinary and human toxicology, 1998, Volume: 40, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Administration, Oral; Animals; Body Weight; CD4-CD8 Ratio; Erythrocy

1998
Increased urinary excretion of thioethers as a marker for detecting exposure to herbicide containing 2,4-dichlorophenoxyacetic acid dimethylamine - experimental study on mice.
    Annals of agricultural and environmental medicine : AAEM, 2000, Volume: 7, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Biomarkers; Body Weight; Creatinine; Dimethylamines; Enviro

2000
Developmental toxicity studies in rats and rabbits on 2,4-dichlorophenoxyacetic acid and its forms.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Ataxia; Body Weight; Dose-Resp

2001
The effect of exposure to a commercial 2,4-D formulation during gestation on the immune response in CD-1 mice.
    Toxicology, 2001, Aug-13, Volume: 165, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Antigens, Surface; Body Weight; Female; Hemolytic Plaque Te

2001
A study of the potential for a herbicide formulation containing 2,4-d and picloram to cause male-mediated developmental toxicity in rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2002, Volume: 68, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Dose-Response Relationship, Drug; Embryonic an

2002
Postnatal survival of rat offspring prenatally exposed to pure 2,4-dichlorophenoxyacetic acid (2,4-D).
    Congenital anomalies, 2002, Volume: 42, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Animals, Newborn; Body Weight; Dose-Response Relationship,

2002
Reproductive success of hens and cockerels originating from eggs sprayed with 2,4-D, 2,4-5-T and picloram followed by early performance of their progency after a comparable in ovo exposure.
    Bulletin of environmental contamination and toxicology, 1978, Volume: 20, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Behavior, Animal; Body W

1978
Prenatal effects of herbicides: evaluation by the prenatal development index.
    Archives of environmental contamination and toxicology, 1977, Volume: 6, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Cleft Palat

1977
Chronic liver injury in phenoxy herbicide-exposed Vietnam veterans.
    Environmental research, 1992, Volume: 59, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Agent Orange; Body Weight; Chemic

1992
Effects of 2,4-dichlorophenoxyacetic acid and picloram on biotransformation, peroxisomal and serum enzyme activities in channel catfish (Ictalurus punctatus).
    Toxicology letters, 1991, Volume: 57, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Acyl Coenzyme A; Animals; Body Weight; Catalase; Chlorides; Cytochro

1991
Effects of chemically induced maternal toxicity on prenatal development in the rat.
    Teratology, 1990, Volume: 42, Issue:6

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Cacodylic A

1990
Toxicity of mixtures of parathion, toxaphene and/or 2,4-D in mice.
    Journal of applied toxicology : JAT, 1990, Volume: 10, Issue:4

    Topics: 2,4-Dichlorophenoxyacetic Acid; Alanine Transaminase; Animals; Body Weight; Brain; Cholinesterases;

1990
Hypocholesterolemic activity of racemic dichlorophenoxypropionic acid or its enantiomers in rats.
    Bulletin of environmental contamination and toxicology, 1987, Volume: 39, Issue:6

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Anticholesteremic Agents; Body Weight; Cholesterol; Clofibr

1987
Acute, pharmacokinetic, and subchronic toxicological studies of 2,4-dichlorophenoxyacetic acid.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1987, Volume: 9, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Administration, Cutaneous; Administration, Oral; Animals; Body Weigh

1987
Lack of neuropathologic consequences of repeated dermal exposure to 2,4-dichlorophenoxyacetic acid in rats.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Administration, Topical; Animals; Body Weight; Kidney; Male; Nervous

1986
Acute and subchronic toxicity of 2,4-dichlorophenol in CD-1 mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Body Weight; Drinking; Female; Lethal Dose 50; Male; Mice;

1985
Effect of external application of pesticides to the fertile egg on hatching success and early chick performance. 2. Commercial-herbicide mixtures of 2,4-D with picloram or 2,4,5-T using the pheasant.
    Bulletin of environmental contamination and toxicology, 1974, Volume: 11, Issue:4

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Anim

1974
The subacture toxicity of 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid to chicks.
    Toxicology and applied pharmacology, 1972, Volume: 21, Issue:3

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Animals; Body Weight; C

1972
Pre- and postnatal studies on 2,4,5-trichlorophenoxyacetic acid, 2,4-dichlorophenoxyacetic acid and their derivatives in rats.
    Toxicology and applied pharmacology, 1972, Volume: 22, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acet

1972
Phenoxy-acid induced renal changes in the chicken. I. Ultrastructure.
    Acta veterinaria Scandinavica, 1971, Volume: 12, Issue:2

    Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Animals; Body Weight; C

1971
Chronic toxicity of 2,4-dichlorophenoxyacetic acid in rats and dogs.
    Toxicology and applied pharmacology, 1971, Volume: 20, Issue:1

    Topics: 2,4-Dichlorophenoxyacetic Acid; Amidohydrolases; Animals; Body Weight; Dogs; Erythrocytes; Esterases

1971