2,4-diaminoquinazoline has been researched along with Adult Spinal Muscular Atrophy in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cherry, JJ; Fadeyi, O; Foley, TL; Gopalsamy, A; Jones, LH; Kyne, RE; LaRosa, G; Liu, S; Loria, PM; Maglich-Goodwin, J; Menard, C; Nabhan, JF; Narayanan, A; Noell, S; Parikh, MD; Petersen, DN; Ren, Y; Rong, H; Tones, MA | 1 |
| Butchbach, MER; Connell, AJ; Gentillon, C; Kirk, RW | 1 |
| Androphy, EJ; Calo, A; Cherry, JJ; Custer, SK; DiDonato, CJ; Du, S; Foley, TL; Gopalsamy, A; Gordo, SM; Gordon, W; Hosea, N; Jones, LH; Krizay, DK; LaRosa, G; Li, H; Mathur, S; Menard, CA; Patel, P; Potter, K; Ramos-Zayas, R; Reedich, EJ; Rietz, A; Rong, H; Tones, MA; Zhang, B | 1 |
| Andrésson, T; Burghes, AH; Butchbach, ME; Edwards, JD; Gurney, ME; Jarecki, J; Pellizzoni, L; Saieva, L; Simard, LR; Singh, J; Slominski, E; Thorsteinsdóttir, M; Thurmond, J; Zhang, J | 1 |
4 other study(ies) available for 2,4-diaminoquinazoline and Adult Spinal Muscular Atrophy
| Article | Year |
|---|---|
Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA).
Topics: Animals; Disease Models, Animal; Drug Design; Endoribonucleases; Enzyme Inhibitors; HEK293 Cells; Humans; Mice; Molecular Docking Simulation; Muscular Atrophy, Spinal; Quinazolines; RNA, Messenger; Survival of Motor Neuron 2 Protein | 2017 |
The effects of C5-substituted 2,4-diaminoquinazolines on selected transcript expression in spinal muscular atrophy cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Cells, Cultured; Humans; Mice; Muscular Atrophy, Spinal; Quinazolines; RNA, Messenger; Survival of Motor Neuron 2 Protein; Transcription, Genetic | 2017 |
In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels.
Topics: Animals; Cell Line; Disease Models, Animal; Endoribonucleases; Enzyme Inhibitors; Female; Gene Knockdown Techniques; HEK293 Cells; Humans; Male; Mice; Mice, Knockout; Muscular Atrophy, Spinal; Promoter Regions, Genetic; Quinazolines; RNA, Messenger; Survival of Motor Neuron 2 Protein | 2017 |
Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy.
Topics: Animals; Cell Survival; Disease Models, Animal; Gene Expression; Humans; Mice; Mice, Knockout; Mice, Transgenic; Motor Neurons; Muscular Atrophy, Spinal; Phenotype; Promoter Regions, Genetic; Quinazolines; Survival of Motor Neuron 2 Protein | 2010 |