2,4,5-trichlorophenoxyacetic acid has been researched along with Pregnancy in 103 studies
2,4,5-Trichlorophenoxyacetic Acid: An herbicide with strong irritant properties. Use of this compound on rice fields, orchards, sugarcane, rangeland, and other noncrop sites was terminated by the EPA in 1985. (From Merck Index, 11th ed)
(2,4,5-trichlorophenoxy)acetic acid : A chlorophenoxyacetic acid that is phenoxyacetic acid in which the ring hydrogens at postions 2, 4 and 5 are substituted by chlorines.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " On days corresponding to days 6 through 14 of pregnancy, groups of pregnant and nonpregnant CD-1 mice and male and nonpregnant female dihybrid cross F2 mice received by gavage 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) ranging in dosage from 30 to 140 mg/kg." | 3.65 | Strain differences in histopathologic, hematologic, and blood chemistry changes induced in mice by a technical and a purified preparation of 2,4,5-trichlorphenoxyacetic acid. ( Gaines, TB; Haley, TJ; Highman, B; Schumacher, HJ, 1976) |
| "Maternal mice were given 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) on days 6 through 14 of pregnancy in a tetratologic study at the National Center for Toxicological Research." | 3.65 | Sequential histopathologic, hematologic, and blood chemistry changes induced in mice by a technical and a purified preparation of 2,4,5-trichlorophenoxyacetic acid. ( Gaines, TB; Highman, B; Schumacher, HJ, 1976) |
| "Agent Orange was composed of two herbicides: 2,4-D and 2,4,5-T, the latter contaminated by small amounts of a highly toxic dioxin (TCDD)." | 2.37 | Does Agent Orange cause birth defects? ( Friedman, JM, 1984) |
| " For the same dose-response relationship, the fit based on the shared response distribution is superior to that based on the beta-binomial, and comparable to that based on the recently proposed q-power distribution (Kuk, 2004, Applied Statistics53, 369-386)." | 1.33 | A shared response model for clustered binary data in developmental toxicity studies. ( Kuk, AY; Pang, Z, 2005) |
| "Modeling of developmental toxicity studies often requires simple parametric analyses of the dose-response relationship between exposure and probability of a birth defect but poses challenges because of nonstandard distributions of birth defects for a fixed level of exposure." | 1.31 | Bayesian semiparametric analysis of developmental toxicology data. ( Dominici, F; Parmigiani, G, 2001) |
| "The risk of intrauterine growth retardation was not increased in any exposure category." | 1.30 | Paternal dioxin, preterm birth, intrauterine growth retardation, and infant death. ( Boyle, CA; Michalek, JE; Rahe, AJ, 1998) |
| "The problem of developing biologically-based dose-response models is addressed for predicting the prevalence of birth defects at low doses of toxic chemicals administered during pregnancy." | 1.28 | Process of building biologically based dose-response models for developmental defects. ( Gaylor, DW; Razzaghi, M, 1992) |
| " Regression and/or probit analyses were conducted to determine whether a dose-response relationship existed." | 1.28 | Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). I. Multireplicated dose-response studies in four inbred strains and one outbred stock of mice. ( Gaines, TB; Gaylor, DW; Holson, JF; LaBorde, JB; Nelson, CJ; Sheehan, DM; Young, JF, 1992) |
| " Both the outcross and outbred mice exhibited a dose-response relationship with each of the above endpoints and the dose-response curves were parallel." | 1.28 | Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). II. Multireplicated dose-response studies with technical and analytical grades of 2,4,5-T in four-way outcross mice. ( Gaines, TB; Holson, JF; LaBorde, JB; McCallum, WF; Nelson, CJ; Sheehan, DM; Wolff, GL; Young, JF, 1992) |
| "The hypothesis that chemically induced overt maternal toxicity induces a characteristic syndrome of adverse developmental effects in the rat was investigated." | 1.28 | Effects of chemically induced maternal toxicity on prenatal development in the rat. ( Chernoff, N; Miller, DB; Rogers, JM; Rosen, MB; Setzer, RW, 1990) |
| "A pharmacokinetic study was conducted in CD-1 mice with the herbicide 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) as a function of dose (15, 30, 60, and 90 mg/kg, iv) and gestational status (nonpregnant, day 6, 10, 13, and 17 of gestation, and postpartum)." | 1.28 | Pharmacokinetics of 2,4,5-T in mice as a function of dose and gestational status. ( Bazare, JJ; Nelson, CJ; Young, JF, 1990) |
| "The frequency of chromosome aberrations in ovulated oocytes at metaphase, II subjected to pyrimethamine and 2,4,5-T, reached 6--8% and exceeded the control value in 5--10 times." | 1.26 | [Nature of cytogenetic and morphologic disorders in rat oogenesis and embryogenesis induced by chloridin and 2,4,5-trichlorophenoxyacetic acid during the preovulatory phase of meiosis]. ( Chebotar', NA, 1980) |
| " While a single-animal, multiple-sample design requires the availability of microanalytical methods, it has many economic and practical advantages and results in a more accurate pharmacokinetic profile of the chemical in mice." | 1.26 | Sampling methods for pharmacokinetic studies in the mouse. ( Bazare, J; Leamons, ML; Young, JF, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (80.58) | 18.7374 |
| 1990's | 11 (10.68) | 18.2507 |
| 2000's | 5 (4.85) | 29.6817 |
| 2010's | 4 (3.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grufferman, S | 1 |
| Lupo, PJ | 1 |
| Vogel, RI | 1 |
| Danysh, HE | 1 |
| Erhardt, EB | 1 |
| Ognjanovic, S | 1 |
| Lewis, RC | 1 |
| Cantonwine, DE | 1 |
| Anzalota Del Toro, LV | 1 |
| Calafat, AM | 1 |
| Valentin-Blasini, L | 1 |
| Davis, MD | 1 |
| Baker, SE | 1 |
| Alshawabkeh, AN | 1 |
| Cordero, JF | 1 |
| Meeker, JD | 1 |
| Schmidt, C | 1 |
| Reagan, LJ | 1 |
| Pang, Z | 1 |
| Kuk, AY | 1 |
| Ngo, AD | 1 |
| Taylor, R | 1 |
| Roberts, CL | 1 |
| Nguyen, TV | 1 |
| Schecter, A | 1 |
| Constable, JD | 1 |
| Thomas, HF | 2 |
| Tedeschi, LG | 1 |
| Friedman, JM | 1 |
| Holden, C | 1 |
| Fagan, K | 1 |
| Pollak, JK | 2 |
| Erickson, JD | 1 |
| Mulinare, J | 1 |
| McClain, PW | 1 |
| Fitch, TG | 1 |
| James, LM | 1 |
| McClearn, AB | 1 |
| Adams, MJ | 1 |
| Gunby, P | 2 |
| Beck, SL | 2 |
| Konstantinova, TK | 5 |
| Shevelo, FS | 2 |
| Crampton, MA | 1 |
| Rogers, LJ | 1 |
| Jensen, DJ | 1 |
| Hummel, RA | 1 |
| Smith, AH | 1 |
| Matheson, DP | 1 |
| Fisher, DO | 1 |
| Chapman, CJ | 1 |
| Czeizel, A | 1 |
| Harsas, W | 1 |
| Chebotar', NA | 2 |
| Bazare, J | 1 |
| Leamons, ML | 1 |
| Young, JF | 4 |
| Smith, FA | 1 |
| Murray, FJ | 1 |
| John, JA | 1 |
| Nitschke, KD | 1 |
| Kociba, RJ | 1 |
| Schwetz, BA | 1 |
| Courtney, KD | 4 |
| Ebron, MT | 2 |
| Stevens, KM | 1 |
| Cook, RR | 1 |
| Coulston, F | 3 |
| Olajos, EJ | 1 |
| George, EO | 2 |
| Bowman, D | 2 |
| Wolfe, WH | 1 |
| Michalek, JE | 2 |
| Miner, JC | 1 |
| Rahe, AJ | 2 |
| Moore, CA | 1 |
| Needham, LL | 1 |
| Patterson, DG | 1 |
| Chen, JJ | 3 |
| Ahn, H | 1 |
| Boyle, CA | 1 |
| Dominici, F | 1 |
| Parmigiani, G | 1 |
| Faddy, MJ | 1 |
| Bosch, RJ | 1 |
| Sare, WM | 3 |
| Forbes, PI | 2 |
| Smith, J | 1 |
| Hood, RD | 1 |
| Patterson, BL | 1 |
| Thacker, GT | 1 |
| Sloan, GL | 1 |
| Szczech, GM | 1 |
| Koshakji, RP | 1 |
| Bush, MT | 1 |
| Harbison, RD | 1 |
| Grebenik, LA | 1 |
| Kirilenko, AI | 1 |
| Cookson, C | 1 |
| Dencker, L | 2 |
| Dougherty, WJ | 2 |
| Golberg, L | 1 |
| Highman, B | 3 |
| Gaines, TB | 5 |
| Schumacher, HJ | 3 |
| Haley, TJ | 1 |
| Herbst, M | 1 |
| Gaylor, DW | 3 |
| Razzaghi, M | 1 |
| Holson, JF | 2 |
| Nelson, CJ | 3 |
| LaBorde, JB | 2 |
| Sheehan, DM | 2 |
| McCallum, WF | 1 |
| Wolff, GL | 1 |
| Chernoff, N | 1 |
| Setzer, RW | 1 |
| Miller, DB | 1 |
| Rosen, MB | 1 |
| Rogers, JM | 1 |
| Bazare, JJ | 1 |
| Mohammad, FK | 3 |
| St Omer, VE | 3 |
| Hatch, MC | 2 |
| Stein, ZA | 2 |
| Cohen, FL | 1 |
| Umbreit, TH | 2 |
| Hesse, EJ | 2 |
| Gallo, MA | 2 |
| Kaye, CI | 1 |
| Rao, S | 1 |
| Simpson, SJ | 1 |
| Rosenthal, FS | 1 |
| Cohen, MM | 1 |
| Pearn, JH | 1 |
| Davies, FG | 1 |
| de Souza, C | 1 |
| Waghela, S | 1 |
| Mohn, S | 1 |
| Neubert, D | 2 |
| Dillmann, I | 1 |
| Lutz-Ostertag, Y | 1 |
| Didier, R | 1 |
| Zens, P | 1 |
| Rothenwallner, A | 1 |
| Merker, HJ | 1 |
| Frohberg, H | 1 |
| Palmer, AK | 1 |
| Waelsch, SG | 1 |
| Hickling, S | 1 |
| Humiczewska, M | 1 |
| Stanosz, S | 1 |
| Sjödén, PO | 1 |
| Söderberg, U | 1 |
| Millard, SA | 1 |
| Hart, MB | 1 |
| Shimek, JF | 1 |
| Fang, SC | 1 |
| Fallin, E | 1 |
| Montgomery, ML | 1 |
| Freed, VH | 1 |
| Sokolik, IIu | 1 |
| Båge, G | 1 |
| Cekanova, E | 1 |
| Larsson, KS | 1 |
| Clegg, DJ | 1 |
| Khera, KS | 1 |
| McKinley, WP | 1 |
| Moore, JA | 1 |
| Sparschu, GL | 1 |
| Dunn, FL | 1 |
| Lisowe, RW | 1 |
| Rowe, VK | 1 |
| Roll, R | 1 |
| Emerson, JL | 1 |
| Thompson, DJ | 1 |
| Strebing, RJ | 1 |
| Gerbig, CG | 1 |
| Robinson, VB | 1 |
7 reviews available for 2,4,5-trichlorophenoxyacetic acid and Pregnancy
| Article | Year |
|---|---|
Association between Agent Orange and birth defects: systematic review and meta-analysis.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 2006 |
Agent Orange. Update.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Adult; Agent Orange; Child, Presc | 1983 |
Does Agent Orange cause birth defects?
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 1984 |
Tissue localization of some teratogens at early and late gestation related to fetal effects.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Cadmium; Cricetinae; Digestive System; Embryo, Mammalian | 1976 |
Paternal contributions to birth defects.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Spontaneous; Adult; Age | 1986 |
Herbicides and congenital malformations: a review for the paediatrician.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acci | 1985 |
Embryotoxicity of chemical contaminants of foods.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Anim | 1971 |
96 other studies available for 2,4,5-trichlorophenoxyacetic acid and Pregnancy
| Article | Year |
|---|---|
Parental military service, agent orange exposure, and the risk of rhabdomyosarcoma in offspring.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Adult; Agent Orange; Case-Control | 2014 |
Urinary biomarkers of exposure to insecticides, herbicides, and one insect repellent among pregnant women in Puerto Rico.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Adolescent; Adult; Biomarkers; DE | 2014 |
The Fog of Agent Orange.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 2016 |
Representations and reproductive hazards of Agent Orange.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Agent Orange; Defoliants, Chemica | 2011 |
A shared response model for clustered binary data in developmental toxicity studies.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Bone and Bones; Computer Simulation; Dose-Response Relat | 2005 |
Commentary: Agent Orange and birth defects in Vietnam.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 2006 |
2,4,5-T use and congenital malformation rates in Hungary.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Environmental Exposure; Fem | 1980 |
Health effects of Agent Orange and dioxin contaminants. Council on scientific affairs.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Accidents, Occupational; Acne Vul | 1982 |
VA study of twins may be canceled.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Agent Orange; Combat Disorders; F | 1984 |
The effect of the phenoxyacetic acid herbicides 2,4,5-trichlorophenoxyacetic acid and 2,4-dichlorophenoxyacetic acid as ascertained by direct experimentation.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Behavior, Animal; Chromo | 1984 |
Vietnam veterans' risks for fathering babies with birth defects.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 1984 |
More questions, not answers, emerge from Agent Orange studies.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 1983 |
Another specific effect of prenatal acetazolamide exposure in the mouse.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Acetazolamide; Animals; Bromodeoxyuridine; Female; Mice; Pesticid | 1983 |
Agent Orange.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Spontaneous; Agent Oran | 1983 |
[Mutagenic activity of the combined action of the herbicides 2,4-D and 2,4,5-T].
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Dose-Response Relationsh | 1983 |
Low doses of 2,4,5-trichlorophenoxyacetic acid are behaviorally teratogenic to rats.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Behavior, Animal; Exploratory Behavior; Female; Humans; | 1983 |
Agent Orange and birth defects.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 1983 |
Secretion of TCDD in milk and cream following the feeding of TCDD to lactating dairy cows.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animal Feed; Animals; Cattle; Dairy Products; Diet; Dioxins; Fema | 1982 |
Report to the Minister of Health of an investigation into allegations of an association between human congenital defects and 2,4,5-T spraying in and around Te Kuiti.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Female; Humans; Infant, Newborn; Pre | 1980 |
Preliminary report of reproductive outcomes among pesticide applicators using 2,4,5-T.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Agricu | 1981 |
Safe as 2, 4, 5-T?
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Female; Humans; Pregnancy; Risk; Ter | 1982 |
Effects of organochlorine compounds on lipid catabolism of foetal rat liver mitochondria and microsomes.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Chlorphenamidine; Female; Hydrocarbons, Chlorinated; In | 1982 |
[Nature of cytogenetic and morphologic disorders in rat oogenesis and embryogenesis induced by chloridin and 2,4,5-trichlorophenoxyacetic acid during the preovulatory phase of meiosis].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Chromosome Aberrations; Cleavage Stage, Ovum; Embryo Los | 1980 |
Sampling methods for pharmacokinetic studies in the mouse.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Administration, Oral; Animals; Bile; Blood Specimen Collection; F | 1981 |
Assessment of adult skeletons to detect prenatal exposure to 2,4,5-T or Trifluralin in mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Bone and Bones; Bone Development; Dose-Response Relation | 1981 |
Three-generation reproduction study of rats ingesting 2,4,5-trichlorophenoxyacetic acid in the diet.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Female; Fertility; Fetus; Male; Organ Size; | 1981 |
2,4,5-T effects on cardiac and serum lactic dehydrogenase (LDH) and creatine kinase (CK) isozymes. II. Neonatal enzyme activities and isozyme profiles.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Animals, Newborn; Creatine Kinase; Female; Isoenzymes; L | 1981 |
2,4,5-T effects on cardiac and serum lactic dehydrogenase (LDH) and creatine kinase (CK) isozymes. I. Maternal enzyme activities and isozyme profiles.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Creatine Kinase; Female; Isoenzymes; L-Lactate Dehydroge | 1981 |
Agent Orange toxicity: a quantitative perspective.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 1981 |
Agent Orange and spontaneous abortions.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Spontaneous; Agent Oran | 1980 |
Dioxin and 2,4,5-T: what are the risks?
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Spontaneous; Carcinogens; Dioxins; Environmental Exposu | 1980 |
Panel report: Panel to Discuss the Epidemiology of 2,4,5-T, New York City, July 10-11, 1979.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Spontaneous; Environmental Exposure; Female; Government | 1980 |
A full likelihood procedure for analysing exchangeable binary data.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Cleft Palate; Female; Fetal Death; Fetal Resorption; Fet | 1995 |
Paternal serum dioxin and reproductive outcomes among veterans of Operation Ranch Hand.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Abor | 1995 |
Estimating variance functions in developmental toxicity studies.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Analysis of Variance; Animals; Biome | 1995 |
Tree-structured logistic models for over-dispersed binomial data with application to modeling developmental effects.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Biometry; Body Weight; Clef | 1997 |
Paternal dioxin, preterm birth, intrauterine growth retardation, and infant death.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Adolescent; Adult; Agent Orange; | 1998 |
Bayesian semiparametric analysis of developmental toxicology data.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Bayes Theorem; Biometry; Da | 2001 |
Likelihood-based modeling and analysis of data underdispersed relative to the Poisson distribution.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Chi-Square Distribution; Data Interpretation, Statistica | 2001 |
2,4,5-T--where next?
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Abortion, Spontaneous; Chemical Phen | 1979 |
The herbicide 2.4.5.-t and its possible dysmorphogenic effects.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Dioxins; Female; Guinea Pig | 1977 |
The safety of the herbicide 2,4,5,-T.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Accident Prevention; Animals; Dioxin | 1977 |
EPA halts most use of herbicide 2,4,5-T.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Spontaneous; Female; Government Agencies; Humans; Legis | 1979 |
Dispute over some herbicides rages in wake of Agent Orange.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Abortion, Spontaneous; Dioxins; Fema | 1979 |
2, 4, 5-T and the problems of toxicity.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Dioxins; Female; Fetus; Humans; Pregnancy | 1979 |
Prenatal effects of 2,4,5-T, 2,4,5-trichlorophenol, and phenoxyacetic acid in mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Body Weight; Chlorophenols; | 1979 |
Metabolism and distribution of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T) in pregnant mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Chromatography, Thin Layer; Countercurrent Distribution; | 1979 |
[Effect of stress (immobilization) on embryotoxic and teratogenic effect of 2,4,5-trichlorophenoxyacetic acid and its derivatives].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Do | 1978 |
'Emergency' ban on 2,4,5-T herbicide in US.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Spontaneous; Environmental Pollutants; Female; Governme | 1979 |
The evaluation of the teratogenic effects of 2, 4, 5-trichlorophenoxyacetic acid in the Rhesus monkey.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Birth Weight; Body Weight; Dioxins; Evaluation Studies a | 1976 |
Retarded development of fetal renal alkaline phosphatase in mice given 2,4,5-trichlorophenoxyacetic acid.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Alkaline Phosphatase; Animals; Depression, Chemical; Female; Fetu | 1977 |
Prenatal effects of herbicides: evaluation by the prenatal development index.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Cleft Palat | 1977 |
Strain differences in histopathologic, hematologic, and blood chemistry changes induced in mice by a technical and a purified preparation of 2,4,5-trichlorphenoxyacetic acid.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Female; Male; Mice; Mice, Inbred Strains; Poisoning; Pre | 1976 |
[Effect of the butyl ester of 2,4,5-T herbicide on embryogenesis in white rats exposed at different periods of pregnancy].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Embryo Implantation; Embryo, Mammalian; Esters; Female; | 1976 |
Tissue localization of some teratogens at early and late gestation related to fetal effects.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Cadmium; Cricetinae; Embryo, Mammalian; Female; Fetus; G | 1976 |
The non-teratogenicity of 2,4,5-trichlorophenoxyacetic acid in the rhesus monkey (Macaca mulatta).
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Birth Weight; Female; Gestational Age; Growth; Macaca mu | 1975 |
Sequential histopathologic, hematologic, and blood chemistry changes induced in mice by a technical and a purified preparation of 2,4,5-trichlorophenoxyacetic acid.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Blood Cell Count; Female; L | 1976 |
Process of building biologically based dose-response models for developmental defects.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Cleft Palate; Disease Model | 1992 |
Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). I. Multireplicated dose-response studies in four inbred strains and one outbred stock of mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Cleft Palate; Dose-Response Relationship, D | 1992 |
Developmental toxicity of 2,4,5-trichlorophenoxyacetic acid (2,4,5-T). II. Multireplicated dose-response studies with technical and analytical grades of 2,4,5-T in four-way outcross mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Dose-Response Relationship, Drug; Female; H | 1992 |
Correlations of developmental end points observed after 2,4,5-trichlorophenoxyacetic acid exposure in mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Embryonic and Fetal Development; Female; Fetal Death; Fe | 1992 |
Effects of chemically induced maternal toxicity on prenatal development in the rat.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Cacodylic A | 1990 |
Pharmacokinetics of 2,4,5-T in mice as a function of dose and gestational status.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Chromatography, Gas; Comput | 1990 |
Developing rat brain monoamine levels following in utero exposure to a mixture of 2,4-dichlorophenoxyacetic and 2,4,5-trichlorophenoxyacetic acids.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Biogenic Amines; Brain C | 1985 |
Agent Orange and risks to reproduction: the limits of epidemiology.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 1986 |
Agent Orange and risks to reproduction: the limits of epidemiology.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Agen | 1987 |
Occupational exposures to chlorophenoxy herbicides.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Ac | 1986 |
Effects of prenatal exposure to 2,4-D/2,4,5-T mixture on postnatal changes in rat brain glutamate, GABA, protein, and nucleic acid levels.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Brain Chemistry; Female; | 1988 |
Reproductive studies of C57B/6 male mice treated with TCDD-contaminated soils from a 2,4,5-trichlorophenoxyacetic acid manufacturing site.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Chemical Industry; Dioxins; Female; Male; Mice; Mice, In | 1988 |
Reproductive toxicity in female mice of dioxin-contaminated soils from a 2,4,5-trichlorophenoxyacetic acid manufacturing site.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Chemical Industry; Dioxins; Female; Male; Mice; Polychlo | 1987 |
Ontogeny of swimming behavior and brain catecholamine turnover in rats prenatally exposed to a mixture of 2,4-dichlorophenoxyacetic and 2,4,5-trichlorophenoxyacetic acids.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Behavior, Animal; Brain; | 1987 |
[The degree of toxicity of the combined effects of chlorophenoxy derivative herbicides on reproductive function of warm-blooded animals, and the problems of their hygienic regulation].
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Anim | 1986 |
Evaluation of chromosomal damage in males exposed to agent orange and their families.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Abor | 1985 |
Possible dioxin poisoning in cattle.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abortion, Veterinary; Animals; Cattle; Cattle Diseases; Dioxins; | 1985 |
Embryotoxic effects in mice treated wtih 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Administration, Oral; Animals; Benzyl Compounds; Body W | 1972 |
[2,4,5 T and embryonal sterility].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acetates; Animals; Chick Embryo; Fem | 1971 |
A survey of the embryotoxic effects of TCDD in mammalian species.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Amines; Animals; Cleft Palate; Cyclo | 1973 |
Proceedings: Investigations on the embryotoxic effect of 2,4,5-T in NMRI-mice.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Aerosols; Animals; Dose-Response Rel | 1974 |
[Experimental effect of the 2,4,5-T butyl ester herbicide on the maternal organism and the fetal development].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Dose-Response Relationship, Drug; Female; Fetus; Maximum | 1974 |
Problems associated with the screening of drugs for possible teratogenic activity.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Aspirin; Dose-Response Rela | 1974 |
[Study of the effect of the butyl ester of 2,4,5-T herbicide on the progency of experimental animals].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Animals; Body Weight; Female; Fetus; Male; Nervous System; Pregna | 1974 |
Possible dysmorphogenic effects of an agricultural chemical: 2.4.5-T.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acetates; Female; Herbicides; Humans | 1972 |
Fetotoxicity.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Antidepressive Agents; Female; Human | 1972 |
Responsibility of individual scientists.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Biological Warfare; Chemical Warfare | 1972 |
Pesticides, health and ecology.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Birds; DDT; Dioxins; Drug C | 1974 |
Influence of protracted administration of phenoxyacetic acid derivatives and nitrogranulogen on alkaline and acid phosphatase and succinic dehydrogenase activities in the liver of guinea pigs.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Acid Phosphatase; Alkal | 1973 |
Sex-dependent effects of prenatal 2,4,5-trichlorophenoxy-acetic acid on rats open-field behavior.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Animals; Animals, Newborn; Dose-Response Relationship, | 1972 |
Enzymes controlling cerebral DNA synthesis: response to 2,4,5-trichlorophenoxyacetic acid and hexachlorophene.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Animals; Brain; Chromatography, Gel; DNA; DNA Nucleotid | 1973 |
The metabolism and distribution of 2,4,5-trichlorophenoxyacetic acid in female rats.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Acetates; Animals; Animals, Newborn; Carbon Dioxide; Carbon Isoto | 1973 |
[Effect of 2,4,5-trichlorophenoxyacetic acid and its butyl ester on rat embryogenesis].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Animals; Female; Pregnancy; Rats | 1973 |
Teratogenic and embryotoxic of the herbicides di- and trichlorophenoxyacetic acids (2,4-D and 2,4,5-T).
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Anim | 1973 |
Pre- and postnatal studies on 2,4,5-trichlorophenoxyacetic acid, 2,4-dichlorophenoxyacetic acid and their derivatives in rats.
Topics: 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acet | 1972 |
Teratology studies with 2,4,5-trichlorophenoxyacetic acid and 2,3,7,8-tetrachlorodibenzo-p-dioxin.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acetates; Animals; Birth Weight; Bod | 1971 |
Study of the effects of high levels of 2,4,5-trichlorophenoxyacetic acid on foetal development in the rat.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acetates; Administration, Oral; Anim | 1971 |
[The teratogenic effects of 2,4,5-T in mice].
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acetates; Administration, Oral; Anim | 1971 |
Teratogenic studies on 2,4,5-trichlorophenoxyacetic acid in the rat and rabbit.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Abnormalities, Drug-Induced; Acetates; Animals; Birth Weight; Fem | 1971 |