2,3-diphosphoglycerate has been researched along with Transfusion Reaction in 10 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Transfusion Reaction: Complications of BLOOD TRANSFUSION. Included adverse reactions are common allergic and febrile reactions; hemolytic (delayed and acute) reactions; and other non-hemolytic adverse reactions such as infections and adverse immune reactions related to immunocompatibility.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relationships among hemoglobin concentration (Hb), red cell 2,3-diphosphoglycerate (2,3-DPG), and p50 were studied in 20 chronically hypertransfused patients with thalassemia major." | 7.67 | Inappropriately low red cell 2,3-diphosphoglycerate and p50 in transfused beta-thalassemia. ( Correra, A; Graziano, JH; Piomelli, S; Seaman, C, 1984) |
| " These metabolic changes include a deprivation of 2,3-diphosphoglycerate (2,3-DPG), acidosis and hyperkalemia." | 4.77 | [Metabolic disorders caused by blood transfusions]. ( Götz, E; Schmitt, HJ, 1988) |
| " Variables analyzed included pH, PCV, and% hemolysis, and lactate, glucose, potassium, sodium, ATP, and 2,3-diphosphoglycerate (2,3-DPG) concentrations." | 3.80 | Effects of four additive solutions on canine leukoreduced red cell concentrate quality during storage. ( Back, FP; González, FH; Hlavac, NR; Jane Wardrop, K; Lacerda, LA; Terra, SR, 2014) |
| "The relationships among hemoglobin concentration (Hb), red cell 2,3-diphosphoglycerate (2,3-DPG), and p50 were studied in 20 chronically hypertransfused patients with thalassemia major." | 3.67 | Inappropriately low red cell 2,3-diphosphoglycerate and p50 in transfused beta-thalassemia. ( Correra, A; Graziano, JH; Piomelli, S; Seaman, C, 1984) |
| "2,3-Diphosphoglycerate levels of GV-treated blood significantly decreased from the 21st to the 28th day in relation to the control." | 1.27 | Metabolism and preservation of fresh and stored erythrocytes in blood treated with gentian violet. ( Barretto, OC; Juliano, Y; Kerbauy, J; Moraes-Souza, H; Nonoyama, K; Pühler, GM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lacerda, LA | 1 |
| Hlavac, NR | 1 |
| Terra, SR | 1 |
| Back, FP | 1 |
| Jane Wardrop, K | 1 |
| González, FH | 1 |
| Almac, E | 1 |
| Ince, C | 1 |
| Correra, A | 1 |
| Graziano, JH | 1 |
| Seaman, C | 1 |
| Piomelli, S | 1 |
| Zauder, HL | 1 |
| Sohmer, PR | 2 |
| Scott, RL | 2 |
| Eichner, ER | 1 |
| Högman, CF | 1 |
| Eriksson, L | 1 |
| Hedlund, K | 1 |
| Wallvik, J | 1 |
| Schmitt, HJ | 1 |
| Götz, E | 1 |
| Moraes-Souza, H | 1 |
| Kerbauy, J | 1 |
| Barretto, OC | 1 |
| Pühler, GM | 1 |
| Nonoyama, K | 1 |
| Juliano, Y | 1 |
3 reviews available for 2,3-diphosphoglycerate and Transfusion Reaction
| Article | Year |
|---|---|
Massive transfusion.
Topics: 2,3-Diphosphoglycerate; Acid-Base Imbalance; Animals; Blood Coagulation Disorders; Blood Preservatio | 1982 |
Metabolic burden of massive transfusion.
Topics: 2,3-Diphosphoglycerate; Ammonia; Blood Glucose; Blood Preservation; Diphosphoglyceric Acids; Energy | 1982 |
[Metabolic disorders caused by blood transfusions].
Topics: 2,3-Diphosphoglycerate; Acidosis; Diphosphoglyceric Acids; Humans; Hyperkalemia; Hypocalcemia; Metab | 1988 |
7 other studies available for 2,3-diphosphoglycerate and Transfusion Reaction
| Article | Year |
|---|---|
Effects of four additive solutions on canine leukoreduced red cell concentrate quality during storage.
Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Animals; Blood Preservation; Cell Survival; | 2014 |
The impact of storage on red cell function in blood transfusion.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Blood Preservation; Blood Transfusion; Eryt | 2007 |
Inappropriately low red cell 2,3-diphosphoglycerate and p50 in transfused beta-thalassemia.
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Blood Preservation; Child; Child, Preschool; Diphosphogly | 1984 |
Clinical problems in the use of blood and blood substitutes.
Topics: 2,3-Diphosphoglycerate; Blood; Blood Substitutes; Blood Transfusion, Autologous; Communicable Diseas | 1982 |
Massive transfusion.
Topics: 2,3-Diphosphoglycerate; Ammonia; Anticoagulants; Blood Glucose; Blood Group Antigens; Blood Preserva | 1982 |
The bottom and top system: a new technique for blood component preparation and storage.
Topics: 2,3-Diphosphoglycerate; Adenosine Monophosphate; Blood Cell Count; Blood Glucose; Blood Preservation | 1988 |
Metabolism and preservation of fresh and stored erythrocytes in blood treated with gentian violet.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adolescent; Adult; Animals; Blood Donors; Blood Pres | 1988 |