Page last updated: 2024-10-15

2,3-diphosphoglycerate and Pregnancy in Diabetes

2,3-diphosphoglycerate has been researched along with Pregnancy in Diabetes in 8 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Research Excerpts

ExcerptRelevanceReference
"2,3-Diphosphoglycerate levels were assayed in 154 pregnant women in third trimester (61 normal, 52 diabetic, 19 with gestational hypertension, 7 with fetal macrosomia, and 15 with idiopathic fetal underdevelopment)."7.672,3-diphosphoglycerate in normal and pathologic pregnancy: relationship to neonatal weight. ( Ferrazzani, S; Francesconi, R; Giorgino, R; Mancuso, S; Paparella, P; Riccardi, P; Zullo, M, 1989)
"In order to evaluate the possible underlying factors for the increase in red cell 2,3-diphosphoglycerate content observed in late diabetic pregnancy, its relationship with serum unconjugated oestriol, human placental lactogen, haemoglobin and hydrogen ion concentrations was investigated in 42 pregnant diabetic women."7.66Correlation of serum unconjugated oestriol to red cell 2,3-diphosphoglycerate levels in diabetic pregnancy. ( Ditzel, J; Madsen, H, 1983)
"2,3-Diphosphoglycerate levels were assayed in 154 pregnant women in third trimester (61 normal, 52 diabetic, 19 with gestational hypertension, 7 with fetal macrosomia, and 15 with idiopathic fetal underdevelopment)."5.282,3-diphosphoglycerate in normal and pathologic pregnancy: relationship to neonatal weight. ( Ferrazzani, S; Francesconi, R; Giorgino, R; Mancuso, S; Paparella, P; Riccardi, P; Zullo, M, 1989)
"Diabetic pregnancy was associated with relative anemia, a significant increase in arterial pH, and hypocapnia."5.27Red cell 2,3-diphosphoglycerate and hemoglobin-oxygen affinity during diabetic pregnancy. ( Ditzel, J; Madsen, H, 1984)
"2,3-Diphosphoglycerate levels were assayed in 154 pregnant women in third trimester (61 normal, 52 diabetic, 19 with gestational hypertension, 7 with fetal macrosomia, and 15 with idiopathic fetal underdevelopment)."3.672,3-diphosphoglycerate in normal and pathologic pregnancy: relationship to neonatal weight. ( Ferrazzani, S; Francesconi, R; Giorgino, R; Mancuso, S; Paparella, P; Riccardi, P; Zullo, M, 1989)
"In order to evaluate the possible underlying factors for the increase in red cell 2,3-diphosphoglycerate content observed in late diabetic pregnancy, its relationship with serum unconjugated oestriol, human placental lactogen, haemoglobin and hydrogen ion concentrations was investigated in 42 pregnant diabetic women."3.66Correlation of serum unconjugated oestriol to red cell 2,3-diphosphoglycerate levels in diabetic pregnancy. ( Ditzel, J; Madsen, H, 1983)
"2,3-Diphosphoglycerate levels were assayed in 154 pregnant women in third trimester (61 normal, 52 diabetic, 19 with gestational hypertension, 7 with fetal macrosomia, and 15 with idiopathic fetal underdevelopment)."1.282,3-diphosphoglycerate in normal and pathologic pregnancy: relationship to neonatal weight. ( Ferrazzani, S; Francesconi, R; Giorgino, R; Mancuso, S; Paparella, P; Riccardi, P; Zullo, M, 1989)
"Diabetic pregnancy was associated with relative anemia, a significant increase in arterial pH, and hypocapnia."1.27Red cell 2,3-diphosphoglycerate and hemoglobin-oxygen affinity during diabetic pregnancy. ( Ditzel, J; Madsen, H, 1984)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Madsen, H6
Ditzel, J5
Kjaergaard, JJ1
Paparella, P1
Francesconi, R1
Zullo, M1
Giorgino, R1
Riccardi, P1
Ferrazzani, S1
Mancuso, S1
Zaretskaya, RB1
Trutneva, KV1
Tartakovskaya, AI1
Antonova, ES1

Reviews

1 review available for 2,3-diphosphoglycerate and Pregnancy in Diabetes

ArticleYear
Fetal oxygenation in diabetic pregnancy. With special reference to maternal blood oxygen affinity and its effectors.
    Danish medical bulletin, 1986, Volume: 33, Issue:2

    Topics: 2,3-Diphosphoglycerate; Anesthesia; Carbon Dioxide; Chorionic Villi; Congenital Abnormalities; Dipho

1986

Other Studies

7 other studies available for 2,3-diphosphoglycerate and Pregnancy in Diabetes

ArticleYear
Red cell 2,3-diphosphoglycerate and hemoglobin-oxygen affinity during diabetic pregnancy.
    Acta obstetricia et gynecologica Scandinavica, 1984, Volume: 63, Issue:5

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Diabetes Mellitus, Type 1; Diphosphoglyceric Acids; Eryth

1984
Blood-oxygen transport in first trimester of diabetic pregnancy.
    Acta obstetricia et gynecologica Scandinavica, 1984, Volume: 63, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diphosphoglycer

1984
Correlation of serum unconjugated oestriol to red cell 2,3-diphosphoglycerate levels in diabetic pregnancy.
    Diabetologia, 1983, Volume: 24, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adult; Diphosphoglyceric Acids; Estriol; Female; Hemoglobins; Humans; Hydrog

1983
Relationship between glycosylation of haemoglobin and the duration of diabetes: a study during the third trimester of pregnancy.
    Diabetologia, 1982, Volume: 22, Issue:1

    Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diphosphoglyceric Acids; Female; Glycated Hemoglobin; Humans;

1982
Changes in red blood cell oxygen transport in diabetic pregnancy.
    American journal of obstetrics and gynecology, 1982, Jun-15, Volume: 143, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adult; Arteries; Diphosphoglyceric Acids; Erythrocytes; Female; Glycated Hem

1982
2,3-diphosphoglycerate in normal and pathologic pregnancy: relationship to neonatal weight.
    American journal of obstetrics and gynecology, 1989, Volume: 160, Issue:3

    Topics: 2,3-Diphosphoglycerate; Birth Weight; Diphosphoglyceric Acids; Female; Fetal Growth Retardation; Fet

1989
Functional condition of the visual analyzer and oxygen metabolism kinetics in pregnant women with diabetes.
    Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985), 1985, Volume: 8, Issue:2-3

    Topics: 2,3-Diphosphoglycerate; Diabetic Retinopathy; Diphosphoglyceric Acids; Erythrocytes; Female; Humans;

1985