2,3-diphosphoglycerate has been researched along with Neoplasms in 5 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hitosugi, T | 1 |
| Zhou, L | 1 |
| Fan, J | 1 |
| Elf, S | 1 |
| Zhang, L | 1 |
| Xie, J | 1 |
| Wang, Y | 2 |
| Gu, TL | 1 |
| Alečković, M | 1 |
| LeRoy, G | 1 |
| Kang, Y | 1 |
| Kang, HB | 1 |
| Seo, JH | 1 |
| Shan, C | 1 |
| Jin, P | 1 |
| Gong, W | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Chen, GZ | 1 |
| Shin, DM | 1 |
| Khuri, FR | 1 |
| Boggon, TJ | 1 |
| Kang, S | 1 |
| He, C | 1 |
| Chen, J | 1 |
| Qu, L | 1 |
| Triulzi, DJ | 1 |
| Cai, WS | 1 |
| Chen, L | 1 |
| Wang, G | 1 |
| Prchal, JT | 1 |
| Pastore, YD | 1 |
| Vora, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Is Intraoperative Red Blood Cells Transfusion With Different Storage Duration Has Effect on Some Biochemical Parameters in Pediatric Trauma Patients Need Intraoperative Transfusion?[NCT02724605] | Phase 2 | 100 participants (Actual) | Interventional | 2016-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for 2,3-diphosphoglycerate and Neoplasms
| Article | Year |
|---|---|
Clinical effects of red blood cell storage.
Topics: 2,3-Diphosphoglycerate; Cardiac Surgical Procedures; Erythrocyte Transfusion; Erythrocytes; Humans; | 2015 |
Erythropoietin and erythropoiesis: polycythemias due to disruption of oxygen homeostasis.
Topics: 2,3-Diphosphoglycerate; Bisphosphoglycerate Mutase; Erythropoiesis; Erythropoietin; Gene Expression | 2004 |
Isozymes of phosphofructokinase.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Chromosome Mapping; | 1982 |
2 other studies available for 2,3-diphosphoglycerate and Neoplasms
| Article | Year |
|---|---|
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.
Topics: 2,3-Diphosphoglycerate; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Enzyme S | 2013 |
Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth.
Topics: 2,3-Diphosphoglycerate; Algorithms; Amino Acid Sequence; Glyceric Acids; Glycolysis; Humans; Hydroge | 2017 |