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2,3-diphosphoglycerate and Methemoglobinemia

2,3-diphosphoglycerate has been researched along with Methemoglobinemia in 1 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Absolute polycythemia is a condition with increased red blood cell mass."2.41Congenital and inherited polycythemia. ( Kralovics, R; Prchal, JT, 2000)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kralovics, R1
Prchal, JT1

Reviews

1 review available for 2,3-diphosphoglycerate and Methemoglobinemia

ArticleYear
Congenital and inherited polycythemia.
    Current opinion in pediatrics, 2000, Volume: 12, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Bisphosphoglycerate Mutase; Child; Erythropoietin; Hemoglobins, Abnor

2000