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2,3-diphosphoglycerate and Metabolic Acidosis

2,3-diphosphoglycerate has been researched along with Metabolic Acidosis in 9 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Research Excerpts

ExcerptRelevanceReference
" These metabolic changes include a deprivation of 2,3-diphosphoglycerate (2,3-DPG), acidosis and hyperkalemia."4.77[Metabolic disorders caused by blood transfusions]. ( Götz, E; Schmitt, HJ, 1988)
" Due to an elevated red cell 2,3-diphosphoglycerate concentration (2,3-DPG) and mild metabolic acidosis, elevated standard and in vivo P50 values (pO2 at 50% oxygen saturation of hemoglobin, sO2) were measured."3.67Increase in Hb-O2-affinity at moderate altitude (2000 m) in patients on maintenance hemodialysis. ( Dittrich, P; Hasibeder, W; Hopferwieser, T; Knapp, E; Mairbäurl, H; Schobersberger, W, 1989)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's2 (22.22)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Moosa, DA1
Al-Obaidi, QT1
Mustafa, NG1
Dahl, MO1
Matveev, SB1
Golikov, PP1
Marchenko, VV1
Golikov, AP1
Riabinin, VA1
Agrafiotis, A1
Camus, F1
Rottembourg, J1
Eugene, L1
Legrain, M1
de Céspedes, C1
Jiménez, R1
Jiménez, E1
Mora, LA1
Carrillo, JM1
Bercovich, CF1
Pirola, CJ1
Finkielman, S1
Nahmod, VE1
Portman, MA1
Ning, XH1
Mairbäurl, H1
Schobersberger, W1
Hasibeder, W1
Knapp, E1
Hopferwieser, T1
Dittrich, P1
Schmitt, HJ1
Götz, E1
Kemp, GJ1
Bevington, A1
Russell, RG1

Reviews

1 review available for 2,3-diphosphoglycerate and Metabolic Acidosis

ArticleYear
[Metabolic disorders caused by blood transfusions].
    Infusionstherapie (Basel, Switzerland), 1988, Volume: 15, Issue:6

    Topics: 2,3-Diphosphoglycerate; Acidosis; Diphosphoglyceric Acids; Humans; Hyperkalemia; Hypocalcemia; Metab

1988

Other Studies

8 other studies available for 2,3-diphosphoglycerate and Metabolic Acidosis

ArticleYear
Concentration of 2,3 bisphosphoglycerate in cattle affected with acute ruminal acidosis.
    Veterinary medicine and science, 2021, Volume: 7, Issue:5

    Topics: 2,3-Diphosphoglycerate; Acidosis; Animals; Cattle; Cattle Diseases

2021
[Gaseous composition of the blood and hemoglobin affinity to oxygen in the acute period of myocardial infarction].
    Kardiologiia, 1983, Volume: 23, Issue:7

    Topics: 2,3-Diphosphoglycerate; Acidosis; Adult; Aged; Arteries; Biological Transport; Diphosphoglyceric Aci

1983
Erythrocyte organic phosphates and whole blood oxygen affinity in patients on continuous ambulatory peritoneal dialysis.
    European journal of clinical investigation, 1982, Volume: 12, Issue:6

    Topics: 2,3-Diphosphoglycerate; Acidosis; Adult; Aged; Blood Urea Nitrogen; Creatinine; Diphosphoglyceric Ac

1982
[2, 3 DPG in anemic children].
    Sangre, 1981, Volume: 26, Issue:4

    Topics: 2,3-Diphosphoglycerate; Acidosis; Anemia; Child; Diphosphoglyceric Acids; Humans

1981
Effects of sodium o-iodobenzoate on acid-base parameters and survival in dogs with hemorrhagic shock.
    Circulatory shock, 1991, Volume: 33, Issue:2

    Topics: 2,3-Diphosphoglycerate; Acidosis; Animals; Bicarbonates; Diphosphoglyceric Acids; Dogs; Erythrocytes

1991
Developmental adaptations in cytosolic phosphate content and pH regulation in the sheep heart in vivo.
    The Journal of clinical investigation, 1990, Volume: 86, Issue:6

    Topics: 2,3-Diphosphoglycerate; Acid-Base Equilibrium; Acidosis; Age Factors; Animals; Animals, Newborn; Blo

1990
Increase in Hb-O2-affinity at moderate altitude (2000 m) in patients on maintenance hemodialysis.
    Clinical nephrology, 1989, Volume: 31, Issue:4

    Topics: 2,3-Diphosphoglycerate; Acidosis; Adult; Altitude; Anemia; Diphosphoglyceric Acids; Erythrocyte Agin

1989
Erythrocyte phosphate metabolism and pH in vitro: a model for clinical phosphate disorders in acidosis and alkalosis.
    Mineral and electrolyte metabolism, 1988, Volume: 14, Issue:5

    Topics: 2,3-Diphosphoglycerate; Acidosis; Alkalosis; Diphosphoglyceric Acids; Erythrocytes; Humans; Hydrogen

1988