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2,3-diphosphoglycerate and Malaria, Falciparum

2,3-diphosphoglycerate has been researched along with Malaria, Falciparum in 3 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.

Research Excerpts

ExcerptRelevanceReference

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Carvalho, M1
Medeiros, MM1
Morais, I1
Lopes, CS1
Balau, A1
Santos, NC1
Carvalho, FA1
Arez, AP1
Dubey, ML1
Hegde, R1
Ganguly, NK1
Mahajan, RC1
Sasi, P1
Burns, SP1
Waruiru, C1
English, M1
Hobson, CL1
King, CG1
Mosobo, M1
Beech, JS1
Iles, RA1
Boucher, BJ1
Cohen, RD1

Other Studies

3 other studies available for 2,3-diphosphoglycerate and Malaria, Falciparum

ArticleYear
2,3-Diphosphoglycerate and the Protective Effect of Pyruvate Kinase Deficiency against Malaria Infection-Exploring the Role of the Red Blood Cell Membrane.
    International journal of molecular sciences, 2023, Jan-10, Volume: 24, Issue:2

    Topics: 2,3-Diphosphoglycerate; Diphosphoglyceric Acids; Erythrocytes; Humans; Malaria; Malaria, Falciparum;

2023
Decreased level of 2,3-diphosphoglycerate and alteration of structural integrity in erythrocytes infected with Plasmodium falciparum in vitro.
    Molecular and cellular biochemistry, 2003, Volume: 246, Issue:1-2

    Topics: 2,3-Diphosphoglycerate; Animals; Erythrocytes; Humans; In Vitro Techniques; Malaria, Falciparum; Osm

2003
Metabolic acidosis and other determinants of hemoglobin-oxygen dissociation in severe childhood Plasmodium falciparum malaria.
    The American journal of tropical medicine and hygiene, 2007, Volume: 77, Issue:2

    Topics: 2,3-Diphosphoglycerate; 3-Hydroxybutyric Acid; Acidosis, Lactic; Animals; Blood Glucose; Child; Chil

2007