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2,3-diphosphoglycerate and Lung Diseases, Obstructive

2,3-diphosphoglycerate has been researched along with Lung Diseases, Obstructive in 8 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.

Research Excerpts

ExcerptRelevanceReference
"The erythrocyte 2,3-diphosphoglycerate (2,3-DPG) was studied in patients with liver diseases, chronic obstructive pulmonary disease, and in normal subjects."7.67Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987)
"The level of 2,3-DPG in hepatocellular carcinoma and/or liver cirrhosis was higher than that in more hypoxic chronic obstructive pulmonary disease."5.27Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987)
"The erythrocyte 2,3-diphosphoglycerate (2,3-DPG) was studied in patients with liver diseases, chronic obstructive pulmonary disease, and in normal subjects."3.67Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987)
"The level of 2,3-DPG in hepatocellular carcinoma and/or liver cirrhosis was higher than that in more hypoxic chronic obstructive pulmonary disease."1.27Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kishi, F1
Palange, P1
Carlone, S1
Serra, P1
Mannix, ET1
Manfredi, F1
Farber, MO1
Ringsted, C1
Eliasen, K1
Gøthgen, IH1
Siggaard-Andersen, O1
Nielsen, C1
Hindsholm, KB1
Nielsen, EM1
Dahl, B1
Nakano, T1
Fujioka, H1
Tamura, S1
Amuro, Y1
Nabeshima, K1
Hada, T1
Higashino, K1
Briguglio, F1
Di Marco, V1
Circosta, C1
Padovano, I1
Ragusa, S1
Saija, A1
Briguglio, E1
Agusti, AG1
Rodriguez-Roisin, R1
Roca, J1
Aguilar, JL1
Agusti-Vidal, A1
Timms, RM1
Tisi, GM1

Trials

1 trial available for 2,3-diphosphoglycerate and Lung Diseases, Obstructive

ArticleYear
Pharmacologic elevation of blood inorganic phosphate in hypoxemic patients with COPD.
    Chest, 1991, Volume: 100, Issue:1

    Topics: 2,3-Diphosphoglycerate; Aged; Carboxyhemoglobin; Diphosphoglyceric Acids; Etidronic Acid; Exercise T

1991

Other Studies

7 other studies available for 2,3-diphosphoglycerate and Lung Diseases, Obstructive

ArticleYear
[The effects of erythrocyte 2,3-diphosphoglycerate on oxygen transport in patients with chronic obstructive pulmonary disease (author's transl)].
    Nihon Kyobu Shikkan Gakkai zasshi, 1981, Volume: 19, Issue:3

    Topics: 2,3-Diphosphoglycerate; Aged; Diphosphoglyceric Acids; Erythrocytes; Humans; Lung Diseases, Obstruct

1981
Positive correlation between 'the arterial oxygen extraction tension' and mixed venous pO2 but lack of correlation between 'the oxygen compensation factor' and cardiac output in 38 patients.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1990, Volume: 203

    Topics: 2,3-Diphosphoglycerate; Adult; Aged; Algorithms; Arteries; Cardiac Output; Diphosphoglyceric Acids;

1990
Blood oxygen parameters in patients with chronic obstructive pulmonary disease. An evaluation of measured and calculated 2,3-diphosphoglycerate concentrations.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1990, Volume: 203

    Topics: 2,3-Diphosphoglycerate; Arteries; Blood; Carbon Dioxide; Diphosphoglyceric Acids; Humans; Hydrogen-I

1990
Erythrocyte 2,3-diphosphoglycerate in liver diseases.
    The American journal of gastroenterology, 1987, Volume: 82, Issue:12

    Topics: 2,3-Diphosphoglycerate; Bile Acids and Salts; Carcinoma, Hepatocellular; Diphosphoglyceric Acids; Er

1987
Metabolic effects of buflomedil hydrochloride.
    The Journal of international medical research, 1985, Volume: 13, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adenylyl Cyclases; Adult; Aged; Arterial Occlusive D

1985
Oxyhemoglobin affinity in patients with chronic obstructive pulmonary disease and acute respiratory failure: role of mechanical ventilation.
    Critical care medicine, 1986, Volume: 14, Issue:7

    Topics: 2,3-Diphosphoglycerate; Aged; Blood Gas Analysis; Critical Care; Diphosphoglyceric Acids; Female; He

1986
The effect of short-term oxygen supplementation on oxygen hemoglobin affinity in patients with chronic obstructive pulmonary disease.
    The American review of respiratory disease, 1985, Volume: 131, Issue:1

    Topics: 2,3-Diphosphoglycerate; Arteries; Carbon Dioxide; Diphosphoglyceric Acids; Erythrocytes; Hemoglobins

1985