2,3-diphosphoglycerate has been researched along with Lung Diseases, Obstructive in 8 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Lung Diseases, Obstructive: Any disorder marked by obstruction of conducting airways of the lung. AIRWAY OBSTRUCTION may be acute, chronic, intermittent, or persistent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The erythrocyte 2,3-diphosphoglycerate (2,3-DPG) was studied in patients with liver diseases, chronic obstructive pulmonary disease, and in normal subjects." | 7.67 | Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987) |
| "The level of 2,3-DPG in hepatocellular carcinoma and/or liver cirrhosis was higher than that in more hypoxic chronic obstructive pulmonary disease." | 5.27 | Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987) |
| "The erythrocyte 2,3-diphosphoglycerate (2,3-DPG) was studied in patients with liver diseases, chronic obstructive pulmonary disease, and in normal subjects." | 3.67 | Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987) |
| "The level of 2,3-DPG in hepatocellular carcinoma and/or liver cirrhosis was higher than that in more hypoxic chronic obstructive pulmonary disease." | 1.27 | Erythrocyte 2,3-diphosphoglycerate in liver diseases. ( Amuro, Y; Fujioka, H; Hada, T; Higashino, K; Nabeshima, K; Nakano, T; Tamura, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kishi, F | 1 |
| Palange, P | 1 |
| Carlone, S | 1 |
| Serra, P | 1 |
| Mannix, ET | 1 |
| Manfredi, F | 1 |
| Farber, MO | 1 |
| Ringsted, C | 1 |
| Eliasen, K | 1 |
| Gøthgen, IH | 1 |
| Siggaard-Andersen, O | 1 |
| Nielsen, C | 1 |
| Hindsholm, KB | 1 |
| Nielsen, EM | 1 |
| Dahl, B | 1 |
| Nakano, T | 1 |
| Fujioka, H | 1 |
| Tamura, S | 1 |
| Amuro, Y | 1 |
| Nabeshima, K | 1 |
| Hada, T | 1 |
| Higashino, K | 1 |
| Briguglio, F | 1 |
| Di Marco, V | 1 |
| Circosta, C | 1 |
| Padovano, I | 1 |
| Ragusa, S | 1 |
| Saija, A | 1 |
| Briguglio, E | 1 |
| Agusti, AG | 1 |
| Rodriguez-Roisin, R | 1 |
| Roca, J | 1 |
| Aguilar, JL | 1 |
| Agusti-Vidal, A | 1 |
| Timms, RM | 1 |
| Tisi, GM | 1 |
1 trial available for 2,3-diphosphoglycerate and Lung Diseases, Obstructive
| Article | Year |
|---|---|
Pharmacologic elevation of blood inorganic phosphate in hypoxemic patients with COPD.
Topics: 2,3-Diphosphoglycerate; Aged; Carboxyhemoglobin; Diphosphoglyceric Acids; Etidronic Acid; Exercise T | 1991 |
7 other studies available for 2,3-diphosphoglycerate and Lung Diseases, Obstructive
| Article | Year |
|---|---|
[The effects of erythrocyte 2,3-diphosphoglycerate on oxygen transport in patients with chronic obstructive pulmonary disease (author's transl)].
Topics: 2,3-Diphosphoglycerate; Aged; Diphosphoglyceric Acids; Erythrocytes; Humans; Lung Diseases, Obstruct | 1981 |
Positive correlation between 'the arterial oxygen extraction tension' and mixed venous pO2 but lack of correlation between 'the oxygen compensation factor' and cardiac output in 38 patients.
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Algorithms; Arteries; Cardiac Output; Diphosphoglyceric Acids; | 1990 |
Blood oxygen parameters in patients with chronic obstructive pulmonary disease. An evaluation of measured and calculated 2,3-diphosphoglycerate concentrations.
Topics: 2,3-Diphosphoglycerate; Arteries; Blood; Carbon Dioxide; Diphosphoglyceric Acids; Humans; Hydrogen-I | 1990 |
Erythrocyte 2,3-diphosphoglycerate in liver diseases.
Topics: 2,3-Diphosphoglycerate; Bile Acids and Salts; Carcinoma, Hepatocellular; Diphosphoglyceric Acids; Er | 1987 |
Metabolic effects of buflomedil hydrochloride.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adenylyl Cyclases; Adult; Aged; Arterial Occlusive D | 1985 |
Oxyhemoglobin affinity in patients with chronic obstructive pulmonary disease and acute respiratory failure: role of mechanical ventilation.
Topics: 2,3-Diphosphoglycerate; Aged; Blood Gas Analysis; Critical Care; Diphosphoglyceric Acids; Female; He | 1986 |
The effect of short-term oxygen supplementation on oxygen hemoglobin affinity in patients with chronic obstructive pulmonary disease.
Topics: 2,3-Diphosphoglycerate; Arteries; Carbon Dioxide; Diphosphoglyceric Acids; Erythrocytes; Hemoglobins | 1985 |