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2,3-diphosphoglycerate and Kidney Failure, Chronic

2,3-diphosphoglycerate has been researched along with Kidney Failure, Chronic in 23 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.

Research Excerpts

ExcerptRelevanceReference
"Hyperphosphatemia is a well-recognized complication of chronic kidney disease, and phosphorus kinetics during hemodialysis (HD) remains a vague area of investigation."3.77Inorganic phosphorus homeostasis during the first hour of dialysis. ( Challa, AS; Dounousi, EC; Karasavvidou, DP; Katopodis, KP; Vlachou, IA, 2011)
"Hyperphosphatemia is a well-recognized complication of chronic kidney disease, and phosphorus kinetics during hemodialysis (HD) remains a vague area of investigation."1.37Inorganic phosphorus homeostasis during the first hour of dialysis. ( Challa, AS; Dounousi, EC; Karasavvidou, DP; Katopodis, KP; Vlachou, IA, 2011)
"03) sampled just before dialysis correlated significantly and positively with the total weekly dosage of erythropoietin given to the patients."1.30Oxygen and 2,3 biphosphoglycerate (2,3-BPG) during haemodialysis. ( Andersen, EM; Jensen, HA; Jørgensen, LG; Nielsen, AL, 1998)
"Eleven patients with chronic renal failure who were being treated with haemodialysis three times a week were monitored for a total of 34 haemodialysis sessions."1.30Oxygen and 2,3 biphosphoglycerate (2,3-BPG) during haemodialysis. ( Andersen, EM; Jensen, HA; Jørgensen, LG; Nielsen, AL, 1998)
"It is well established that ESRD patients can tolerate a greater degree of anaemia than anaemic subjects of other aetiologies."1.28Adaptation of uraemic patients to anaemia: A31 P nuclear magnetic resonance study. ( Baz, M; Berland, Y; Crevat, A; Elsen, R; Klinkmann, H; Monti, JP, 1990)
"In a group of 69 patients with chronic renal failure, 18 patients after renal transplantation and 8 healthy controls the influence of inorganic phosphate and pH of plasma and of the hemoglobin concentration in whole blood on the 2,3-DPG concentration in red blood cells was investigated."1.262,3-Biphosphoglycerate, inorganic phosphate, pH and hemoglobin concentration in chronic renal failure of man. ( Elsner, R; Gerber, G; Holzhütter, H; Rapoport, I; Röseler, E, 1981)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199013 (56.52)18.7374
1990's6 (26.09)18.2507
2000's2 (8.70)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peng, Z1
Luo, R1
Xie, T1
Zhang, W1
Liu, H1
Wang, W1
Tao, L1
Kellems, RE1
Xia, Y1
Katopodis, KP1
Dounousi, EC1
Challa, AS1
Vlachou, IA1
Karasavvidou, DP1
Monti, JP2
Baz, M1
Klinkmann, H1
Elsen, R1
Berland, Y1
Crevat, A1
Bober, J1
Kedzierska, K1
Safranow, K1
Kwiatkowska, E1
Jakubowska, K1
Herdzik, E1
Dołegowska, B1
Domański, L1
Ciechanowski, K1
Kang, SK1
Park, SK1
Oimomi, M1
Ishikawa, K1
Kawasaki, T1
Kubota, S1
Takagi, K1
Tanke, G1
Yoshimura, Y1
Takase, S1
Sato, E1
Baba, S1
Agrafiotis, A1
Camus, F1
Rottembourg, J1
Eugene, L1
Legrain, M1
Gerber, G1
Holzhütter, H2
Röseler, E1
Rapoport, I2
Elsner, R1
Summerfield, GP1
Bellingham, AJ1
Manlove, L1
Forbes, AM1
Goldsmith, HJ1
Rubio Pérez, P1
Alvarez-Sala Walther, JL1
Gallardo López, J1
Naranjo Gómez, P1
de Pablos Mateos, I1
Rentero Rodríguez, RM1
Sánchez Sánchez, ML1
Espinós Pérez, D1
Heierli, C1
Thölen, H1
Brunet, PJ1
Berland, YF1
Vanuxem, DC1
Vanuxem, PA1
Crevat, AD1
Rodriguez-Franco, F1
Tesouro-Diez, MA1
Rodriguez-Sanchez, M1
Wehler, M1
Grote, J1
Klehr, HU1
Nielsen, AL1
Andersen, EM1
Jørgensen, LG1
Jensen, HA1
Umimoto, K1
Hirai, Y1
Hayashi, T1
Tanaka, H1
Engelhardt, I1
Drung, I1
Schmidt, G1
Jabłońska-Skwiecinśka, E2
Staniszewska, K2
Kowalska, H2
Caimi, G1
Vaccaro, F1
Romano, A1
Serra, A1
Picone, FP1
D'Asaro, S1
Catania, A1
Sarno, A1
Ando, R1
Saito, H1
Takeuchi, J1
Solomon, LR1
Hendler, ED1
Martins e Silva, J1

Reviews

1 review available for 2,3-diphosphoglycerate and Kidney Failure, Chronic

ArticleYear
[Erythrocyte mechanisms of adaptation to hypoxia in chronic renal insufficiency].
    Acta medica portuguesa, 1985, Volume: 6, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Adenosine Triphosphate; Anemia; Animals; Diphosph

1985

Other Studies

22 other studies available for 2,3-diphosphoglycerate and Kidney Failure, Chronic

ArticleYear
Erythrocyte Adenosine A2B Receptor-Mediated AMPK Activation: A Missing Component Counteracting CKD by Promoting Oxygen Delivery.
    Journal of the American Society of Nephrology : JASN, 2019, Volume: 30, Issue:8

    Topics: 2,3-Diphosphoglycerate; Adult; AMP-Activated Protein Kinases; Angiotensin II; Animals; Disease Progr

2019
Inorganic phosphorus homeostasis during the first hour of dialysis.
    Renal failure, 2011, Volume: 33, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adult; Aged; Aged, 80 and over; Biomarkers; Erythrocytes; Female; Follow-Up

2011
Adaptation of uraemic patients to anaemia: A31 P nuclear magnetic resonance study.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1990, Volume: 5, Issue:8

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Anemia; Case-Control Studies; Erythrocytes; Hemog

1990
Influence of glucose in dialyzing fluid on purine concentrations in hemodialyzed patients with chronic renal failure.
    Nephron. Clinical practice, 2003, Volume: 95, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Dialysis Solutions; Erythrocytes; Femal

2003
2,3-diphosphoglyceric acid changes in uremia and during hemodialysis.
    The Korean journal of internal medicine, 1986, Volume: 1, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Blood Glucose; Female; Humans; Hydrogen-Ion Concentration; Kidney Fai

1986
[Studies on hemorheology as causative factors of tissue hypoxia in renal failure].
    Nihon Jinzo Gakkai shi, 1983, Volume: 25, Issue:4

    Topics: 2,3-Diphosphoglycerate; Blood Viscosity; Diphosphoglyceric Acids; Glycated Hemoglobin; Humans; Hypox

1983
Erythrocyte organic phosphates and whole blood oxygen affinity in patients on continuous ambulatory peritoneal dialysis.
    European journal of clinical investigation, 1982, Volume: 12, Issue:6

    Topics: 2,3-Diphosphoglycerate; Acidosis; Adult; Aged; Blood Urea Nitrogen; Creatinine; Diphosphoglyceric Ac

1982
2,3-Biphosphoglycerate, inorganic phosphate, pH and hemoglobin concentration in chronic renal failure of man.
    Acta biologica et medica Germanica, 1981, Volume: 40, Issue:4-5

    Topics: 2,3-Diphosphoglycerate; Diphosphoglyceric Acids; Hemoglobins; Humans; Hydrogen-Ion Concentration; Ki

1981
Erythrocyte metabolism in patients on haemodialysis and continuous ambulatory peritoneal dialysis.
    Clinical science (London, England : 1979), 1982, Volume: 62, Issue:5

    Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diphosphoglyceric Acids; Erythrocytes; Glycolysis; Hemoglobin

1982
[Changes in erythrocyte levels of 2,3-diphosphoglyceric acid in patients with severe chronic renal insufficiency].
    Revista clinica espanola, 1981, May-15, Volume: 161, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adult; Aged; Anemia; Diphosphoglyceric Acids; Erythrocytes; Female; Humans;

1981
Metabolites of glucose in the blood of patients with renal failure.
    Klinische Wochenschrift, 1981, May-04, Volume: 59, Issue:9

    Topics: 2,3-Diphosphoglycerate; Acetaldehyde; Acetates; Acetoin; Adult; Aged; Blood Glucose; Butylene Glycol

1981
Opposite effects of urea on hemoglobin-oxygen affinity in anemia of chronic renal failure.
    Kidney international, 1995, Volume: 48, Issue:3

    Topics: 2,3-Diphosphoglycerate; Anemia; Diphosphoglyceric Acids; Hemoglobins; Humans; Kidney Failure, Chroni

1995
Concentrations of 2,3-diphosphoglycerate (2,3-DPG) in canine blood (healthy dogs, dogs with cardiopulmonary insufficiency and dogs with renal insufficiency).
    Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B, 1994, Volume: 41, Issue:1

    Topics: 2,3-Diphosphoglycerate; Animals; Diphosphoglyceric Acids; Dog Diseases; Dogs; Female; Heart Diseases

1994
Hemoglobin oxygen affinity and acid-base status in blood of chronic hemodialysis patients.
    Advances in experimental medicine and biology, 1994, Volume: 345

    Topics: 2,3-Diphosphoglycerate; Acetates; Acid-Base Equilibrium; Adult; Aged; Bicarbonates; Carbon Dioxide;

1994
Oxygen and 2,3 biphosphoglycerate (2,3-BPG) during haemodialysis.
    Scandinavian journal of clinical and laboratory investigation, 1998, Volume: 58, Issue:6

    Topics: 2,3-Diphosphoglycerate; Aged; Erythropoietin; Female; Hemoglobins; Humans; Kidney Failure, Chronic;

1998
The effect of biofiltration on red blood cells 2.3-diphosphoglycerate and pH.
    Artificial organs, 2000, Volume: 24, Issue:12

    Topics: 2,3-Diphosphoglycerate; Bicarbonates; Cross-Over Studies; Diabetic Nephropathies; Erythrocytes; Hemo

2000
Influence of erythropoietin treatment on 2,3-bisphosphoglycerate and O2-affinity of red blood cells in children with renal anemia.
    Biomedica biochimica acta, 1990, Volume: 49, Issue:2-3

    Topics: 2,3-Diphosphoglycerate; Adolescent; Anemia; Diphosphoglyceric Acids; Erythrocytes; Erythropoietin; F

1990
The red cell sodium, potassium, inorganic phosphate, ATP and 2,3DPG concentrations in chronic renal failure.
    Folia haematologica (Leipzig, Germany : 1928), 1987, Volume: 114, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Diphosphoglyceric Acids; Erythrocytes; Humans; Kidne

1987
[Chronic renal insufficiency undergoing conservative therapy: hemorheological pattern and erythrocytic metabolic parameters].
    La Ricerca in clinica e in laboratorio, 1989, Volume: 19 Suppl 1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Diphosphoglyceric Acids; Erythrocyte Ag

1989
[Sodium, potassium, ATP, 2,3-diphosphoglycerate and inorganic phosphate levels in erythrocytes of patients on hemodialysis].
    Polskie Archiwum Medycyny Wewnetrznej, 1988, Volume: 79, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Diphosphoglyceric Acids; Erythrocytes; Female

1988
Factors that affect oxygen affinity of hemoglobin in chronic hemodialysis patients.
    Nephron, 1987, Volume: 46, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adult; Carbon Dioxide; Diabetic Nephropathies; Diphosphoglyceric Acids; Eryt

1987
Androgen therapy in haemodialysis patients. II. Effects on red cell metabolism.
    British journal of haematology, 1987, Volume: 65, Issue:2

    Topics: 2,3-Diphosphoglycerate; Androgens; Diphosphoglyceric Acids; Erythrocyte Count; Erythrocytes; Humans;

1987