Page last updated: 2024-10-15

2,3-diphosphoglycerate and Ischemia

2,3-diphosphoglycerate has been researched along with Ischemia in 2 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Resnick, LM1
Gupta, RK1
Barbagallo, M1
Laragh, JH1
Tomson, CR1
Channon, SM1
Ward, MK1
Laker, MF1

Other Studies

2 other studies available for 2,3-diphosphoglycerate and Ischemia

ArticleYear
Is the higher incidence of ischemic disease in patients with hypertension and diabetes related to intracellular depletion of high energy metabolites?
    The American journal of the medical sciences, 1994, Volume: 307 Suppl 1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Diabetes Mellitus, Type 2; Diphosphoglyceric Acids;

1994
Ascorbate-induced hyperoxalaemia has no significant effect on lactate generation or erythrocyte 2,3,diphosphoglycerate in dialysis patients.
    European journal of clinical investigation, 1990, Volume: 20, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adult; Ascorbic Acid; Diphosphoglyceric Acids; Erythrocytes; Forearm; Humans

1990