Page last updated: 2024-10-15

2,3-diphosphoglycerate and Hypocalcemia

2,3-diphosphoglycerate has been researched along with Hypocalcemia in 2 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" These metabolic changes include a deprivation of 2,3-diphosphoglycerate (2,3-DPG), acidosis and hyperkalemia."4.77[Metabolic disorders caused by blood transfusions]. ( Götz, E; Schmitt, HJ, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zauder, HL1
Schmitt, HJ1
Götz, E1

Reviews

2 reviews available for 2,3-diphosphoglycerate and Hypocalcemia

ArticleYear
Massive transfusion.
    International anesthesiology clinics, 1982,Winter, Volume: 20, Issue:4

    Topics: 2,3-Diphosphoglycerate; Acid-Base Imbalance; Animals; Blood Coagulation Disorders; Blood Preservatio

1982
[Metabolic disorders caused by blood transfusions].
    Infusionstherapie (Basel, Switzerland), 1988, Volume: 15, Issue:6

    Topics: 2,3-Diphosphoglycerate; Acidosis; Diphosphoglyceric Acids; Humans; Hyperkalemia; Hypocalcemia; Metab

1988