Page last updated: 2024-10-15

2,3-diphosphoglycerate and Hemolysis

2,3-diphosphoglycerate has been researched along with Hemolysis in 75 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
"To investigate the anti-oxidative effect of ethyl pyruvate (EP) and taurine (TAU) on the quality of red blood cells stored at 4±2 ℃, hemolysis, energy metabolism and lipid peroxidation of the red blood cells in the preservation solution were studied at different intervals."4.12[Effect of Anti-Oxidative of Ethyl Pyruvate and Taurine on the Red Blood Cell Storage at 4 ℃]. ( Gao, SH; Gao, SQ; Ren, LX; Yuan, XY; Zhu, CH, 2022)
" The hemolysis index, lactate and potassium concentrations, prothrombin time (PT), activated partial thromboplastin time (aPTT), and fibrinogen were measured on plasma aliquots."3.88In vitro assessment of quality of citrate-phosphate-dextrose-adenine-1 preserved feline blood collected by a commercial closed system. ( Bozzato, E; Capello, K; Carminato, A; Corrò, M; Crestani, C; Cro, A; Mutinelli, F; Stefani, A; Vascellari, M, 2018)
" RBC units were assessed using an extensive panel of in vitro tests, encompassing regulated quality control criteria such as hematocrit (Hct), hemolysis, and hemoglobin (Hb) levels, as well as adenosine triphosphate, 2,3-diphosphoglycerate, extracellular K(+) and Na(+) levels, methemoglobin, p50, RBC indices, and morphology."3.80A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing. ( Acker, JP; Croteau, I; Hansen, AL; Jenkins, C; Kurach, JD; Turner, TR, 2014)
" Variables analyzed included pH, PCV, and% hemolysis, and lactate, glucose, potassium, sodium, ATP, and 2,3-diphosphoglycerate (2,3-DPG) concentrations."3.80Effects of four additive solutions on canine leukoreduced red cell concentrate quality during storage. ( Back, FP; González, FH; Hlavac, NR; Jane Wardrop, K; Lacerda, LA; Terra, SR, 2014)
" The addition of AGE significantly inhibited an increase in thiobarbituric acid-reactive substances (TBARS) and hemolysis rate and prevented the loss of intraerythrocytic ATP and 2,3-diphosphoglycerate (2,3-DPG) in oxidized erythrocytes."3.71The effects of aged garlic extract on lipid peroxidation and the deformability of erythrocytes. ( Itakura, Y; Moriguchi, T; Takasugi, N, 2001)
" Cell function parameters, including red cell indices, pH, methemoglobin, carboxyhemoglobin, osmotic fragility, hemolysis, 2,3-diphosphoglycerate, cholinesterase, ATP, and antigen typing of treated cells were compared to controls."3.70Seroconversion of type B to O erythrocytes using recombinant Glycine max alpha-D-galactosidase. ( Evans, ML; Harmata, MA; Johnson, SA; Li, CQ; Mitra, MM; Smith, DS; Vosnidou, NC; Walker, JC; Wells, DC, 1998)
"To induce anemia experimentally in rats to provide a hematocrit of 30 to 35% and provide data about the physiologic response to anemia during induction and after it is established, two methods were selected: the application of repetitive doses of phenylhydrazine and bleeding."3.69Physiological response to experimentally induced anemia in rats: a comparative study. ( Alvarez, AI; Diez, C; Fernández-Rojo, F; Prieto, JG; Redondo, PA, 1995)
" Hemolysis, ATP, 2,3-diphosphoglycerate (2,3-DPG), glucose, electrolytes, lactate, hematocrit, Hb and pH were quantified weekly."3.69[Effect of whole blood preparation and leukocyte filtration on storage of erythrocyte concentrates over 42 days]. ( Janetzko, K; Kirchner, H; Klüter, H; Müller-Steinhardt, M, 1997)
" In isoosmotic sucrose solutions, the osmotic hemolysis curve is shifted to the left (less fragile) within several hours at 37 degrees C and within several days at 4 degrees C."3.66Isoosmotic sucrose, adenine, inosine media for preservation of blood. ( Komatsu, Y; Nakao, M; Nakao, T; Sano, K; Sasakawa, S, 1983)
"RBC 2,3-diphosphoglycerate acid levels were substantially less after the 24-hour hold compared to after the 8-hour hold (n = 18; p < 0."1.37Evaluation of the properties of components prepared and stored after holding of whole blood units for 8 and 24 hours at ambient temperature. ( AuBuchon, JP; Heaton, WA; Holme, S; Moroff, G; Pickard, C; Whitley, PH, 2011)
"Haemolysis was below the 0·8% U."1.37Red cell concentrate storage and transport temperature. ( Cardigan, R; Hancock, V; Thomas, S, 2011)
"The severe adverse events observed in patients who received hemoglobin based oxygen carriers (HBOCs) were associated with the Ringer's D."1.35The effects of preserved red blood cells on the severe adverse events observed in patients infused with hemoglobin based oxygen carriers. ( Ragno, G; Valeri, CR, 2008)
"Hemolysis was at 0."1.33Storage of red blood cells with improved maintenance of 2,3-bisphosphoglycerate. ( Högman, CF; Löf, H; Meryman, HT, 2006)
"Hemolysis was very low in both systems, 0."1.31Improved maintenance of 2,3 DPG and ATP in RBCs stored in a modified additive solution. ( Högman, CF; Knutson, F; Lööf, H; Payrat, JM, 2002)
"RBC hemolysis was less than 1 percent after 42 days of storage, and no changes in RBC antigens were observed."1.31Process for the preparation of pathogen-inactivated RBC concentrates by using PEN110 chemistry: preclinical studies. ( Chapman, J; Dzik, W; Lazo, A; Pivacek, L; Purmal, A; Ragno, G; Valeri, CR, 2002)
"2,3-Diphosphoglycerate was induced only during the recovery phase of the study and corresponded to a gradual response to hypoxia."1.29Physiological response to experimentally induced anemia in rats: a comparative study. ( Alvarez, AI; Diez, C; Fernández-Rojo, F; Prieto, JG; Redondo, PA, 1995)

Research

Studies (75)

TimeframeStudies, this research(%)All Research%
pre-199013 (17.33)18.7374
1990's19 (25.33)18.2507
2000's16 (21.33)29.6817
2010's26 (34.67)24.3611
2020's1 (1.33)2.80

Authors

AuthorsStudies
Gao, SQ1
Gao, SH1
Zhu, CH1
Yuan, XY1
Ren, LX1
Lelkens, CCM1
Lagerberg, JWM1
de Korte, D6
Sun, K1
D'Alessandro, A2
Ahmed, MH1
Zhang, Y1
Song, A1
Ko, TP1
Nemkov, T1
Reisz, JA1
Wu, H1
Adebiyi, M1
Peng, Z1
Gong, J3
Liu, H1
Huang, A1
Wen, YE1
Wen, AQ1
Berka, V1
Bogdanov, MV1
Abdulmalik, O1
Han, L1
Tsai, AL1
Idowu, M1
Juneja, HS1
Kellems, RE1
Dowhan, W1
Hansen, KC1
Safo, MK1
Xia, Y1
Hebbel, RP1
Hedlund, BE1
Crestani, C1
Stefani, A1
Carminato, A1
Cro, A1
Capello, K1
Corrò, M1
Bozzato, E1
Mutinelli, F1
Vascellari, M1
Smethurst, PA1
Jolley, J1
Braund, R1
Proffitt, S1
Lynes, T1
Hazell, M1
Mellor, P1
Ridgwell, K1
Procter, S1
Griffiths, A1
Marinaki, AM1
New, HV1
Murphy, GJ1
Edmondson, D1
Cardigan, R5
Radwanski, K1
Garraud, O1
Cognasse, F1
Hamzeh-Cognasse, H1
Payrat, JM4
Min, K1
Gulliksson, H2
Nordahl-Källman, AS1
Hess, JR4
Winter, KM1
Johnson, L1
Kwok, M1
Vidovic, D1
Hyland, RA1
Mufti, N1
Erickson, A1
Marks, DC1
Acker, JP1
Hansen, AL1
Kurach, JD1
Turner, TR1
Croteau, I1
Jenkins, C1
Lacerda, LA1
Hlavac, NR1
Terra, SR1
Back, FP1
Jane Wardrop, K1
González, FH1
Eckstein, M1
Zimmermann, R3
Roth, T1
Hauck-Dlimi, B1
Strasser, EF2
Xiang, W1
Ercis, K1
Aydoğan, S1
Atayoğlu, AT1
Silici, S1
Mambrini, G1
Mandolini, M1
Rossi, L1
Pierigè, F1
Capogrossi, G1
Salvati, P1
Serafini, S1
Benatti, L1
Magnani, M1
Meinke, S1
Ravizza, A1
Larsson, L1
Höglund, P1
Bontekoe, IJ2
van der Meer, PF3
Wilsher, C1
Garwood, M1
Sutherland, J1
Turner, C1
Liumbruno, G1
Grazzini, G1
Zolla, L1
Burger, P1
Korsten, H1
Rombout, E1
Van Bruggen, R1
Verhoeven, AJ3
Hauck, B1
Oremek, D1
Ruppel, R1
Troester, B1
Eckstein, R2
Hornsey, VS1
Casey, C1
McColl, K1
Young, H1
Drummond, O1
McMillan, L1
Morrison, A1
Prowse, CV1
Moroff, G2
AuBuchon, JP3
Pickard, C1
Whitley, PH1
Heaton, WA1
Holme, S1
Hancock, V2
Thomas, S2
Weiss, DR1
Goehring, J1
Weisbach, V1
Ringwald, J1
Otani, T1
Oki, K1
Akino, M1
Tamura, S1
Naito, Y1
Homma, C1
Ikeda, H1
Sumita, S1
Hill, HR2
Oliver, CK2
Lippert, LE2
Greenwalt, TJ4
Högman, CF7
Knutson, F1
Lööf, H1
Rugg, N1
Joines, AD1
Gormas, JF1
Pratt, PG1
Silverstein, EB1
Kagen, LR1
Simon, T1
Brand, A1
Lockwood, W1
Zanella, A1
Adamson, J1
Snyder, E1
Taylor, HL1
Hogman, C1
Elfath, MD1
Löf, H1
Meryman, HT1
Niinistö, K1
Raekallio, M1
Sankari, S1
Valeri, CR3
Ragno, G3
Kleine, M1
Korsten, HG1
Purdie, A1
Wells, RM1
Brittain, T1
Vora, S1
Nakao, M1
Nakao, T1
Komatsu, Y1
Sano, K1
Sasakawa, S1
McGrath, KM1
Collecutt, MF1
Gordon, A1
Sawers, RJ1
Faragher, BS1
Beutler, E1
West, C1
Castro, O2
Eichner, ER1
Eriksson, L5
Debrauwere, J2
Högman, AB1
Vikholm, K1
Stewart, M1
Wagner, SJ2
Storry, JR1
Mallory, DA2
Stromberg, RR1
Benade, LE1
Friedman, LI1
Coppola, L1
Giunta, R1
Verrazzo, G1
Luongo, C1
Sammartino, A1
Vicario, C1
Giugliano, D1
Redondo, PA1
Alvarez, AI1
Diez, C1
Fernández-Rojo, F1
Prieto, JG1
Zhang, H1
Weir, B1
Marton, LS1
Macdonald, RL1
Bindokas, V1
Miller, RJ1
Brorson, JR1
Waters, SI1
Sen, R1
Brunauer, LS1
Huestis, WH1
Müller-Steinhardt, M2
Janetzko, K1
Kirchner, H2
Klüter, H1
Poillon, WN1
Kim, BC1
Solheim, BG1
Bergerud, UE1
Kjeldsen-Kragh, J1
Brosstad, F1
Mollnes, TE1
Schutz, R1
Skripchenko, A1
Robinette, D1
Cincotta, L1
Vosnidou, NC1
Johnson, SA1
Mitra, MM1
Wells, DC1
Li, CQ1
Evans, ML1
Harmata, MA1
Walker, JC1
Smith, DS1
Arun, P1
Padmakumaran Nair, KG1
Manojkumar, V1
Deepadevi, KV1
Lakshmi, LR1
Kurup, PA1
Moriguchi, T1
Takasugi, N1
Itakura, Y1
Pivacek, LE1
Cassidy, GP1
Purmal, A2
Dzik, W1
Pivacek, L1
Lazo, A1
Chapman, J2
Pickard, CA1
Herschel, LH1
Roger, JC1
Tracy, JE1
Ackerman, S1
Beach, KJ1
Hennig, H1
Schlenke, P1
Rittmeyer, IC1
Nydegger, UE1
Dumaswala, UJ1
Oreskovic, RT1
Petrosky, TL1
Kaiser, M1
Scholz, M1
Strauss, D1
Ericson, A1
Reppucci, AJ1
Mori, K1
Inoue, N1
Fujishiro, K1
Kikuchi, M1
Chiba, S1
Hellwig, U1
Angué, M1
Chatelain, P1
Fiabane, S1
Domy, M1
Guignier, F1
Richaud, P1
Almaraz, L1
García-Sancho, J1
Hedlund, K1
Wallvik, J1
Stus', LK1
Loevskiĭ, MM1
Lipina, OV1
Gordienko, OI1
Kuraksa, VM1
Reeves, RB1
Morin, RA1
Martins e Silva, J1

Reviews

5 reviews available for 2,3-diphosphoglycerate and Hemolysis

ArticleYear
Measures of stored red blood cell quality.
    Vox sanguinis, 2014, Volume: 107, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Preservation; Erythrocytes; Hemolysis; Humans;

2014
Red blood cell storage: the story so far.
    Blood transfusion = Trasfusione del sangue, 2010, Volume: 8, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anaerobiosis; Anticoagulants; Blood Preservation; Ce

2010
Quality determinants of erythrocyte destined for transfusion.
    Cellular and molecular biology (Noisy-le-Grand, France), 2004, Volume: 50, Issue:2

    Topics: 2,3-Diphosphoglycerate; Animals; Blood Preservation; Erythrocyte Transfusion; Erythrocytes; Hemolysi

2004
Isozymes of phosphofructokinase.
    Isozymes, 1982, Volume: 6

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Chromosome Mapping;

1982
[Erythrocyte mechanisms of adaptation to hypoxia in chronic renal insufficiency].
    Acta medica portuguesa, 1985, Volume: 6, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Adenosine Triphosphate; Anemia; Animals; Diphosph

1985

Trials

1 trial available for 2,3-diphosphoglycerate and Hemolysis

ArticleYear
Production of pathogen-inactivated RBC concentrates using PEN110 chemistry: a Phase I clinical study.
    Transfusion, 2002, Volume: 42, Issue:2

    Topics: 2,3-Diphosphoglycerate; ABO Blood-Group System; Adenosine Triphosphate; Adult; Blood Donors; Blood G

2002

Other Studies

69 other studies available for 2,3-diphosphoglycerate and Hemolysis

ArticleYear
[Effect of Anti-Oxidative of Ethyl Pyruvate and Taurine on the Red Blood Cell Storage at 4 ℃].
    Zhongguo shi yan xue ye xue za zhi, 2022, Volume: 30, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Blood Preservation; Citrates; Erythrocytes;

2022
The effect of prefreeze rejuvenation on postthaw storage of red blood cells in AS-3 and SAGM.
    Transfusion, 2017, Volume: 57, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Blood Preservation; Erythrocytes; Freezing;

2017
Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease.
    Scientific reports, 2017, 11-10, Volume: 7, Issue:1

    Topics: 2,3-Diphosphoglycerate; Anemia, Sickle Cell; Animals; Erythrocytes, Abnormal; Female; Hemoglobin A;

2017
Sickle hemoglobin oxygen affinity-shifting strategies have unequal cerebrovascular risks.
    American journal of hematology, 2018, Volume: 93, Issue:3

    Topics: 2,3-Diphosphoglycerate; Anemia, Sickle Cell; Benzaldehydes; Cerebrovascular Circulation; Cerebrovasc

2018
In vitro assessment of quality of citrate-phosphate-dextrose-adenine-1 preserved feline blood collected by a commercial closed system.
    Journal of veterinary internal medicine, 2018, Volume: 32, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Blood Cell Count; Blood Preservation; Blood

2018
Rejuvenation of RBCs: validation of a manufacturing method suitable for clinical use.
    Transfusion, 2019, Volume: 59, Issue:9

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Grouping and Crossmatching; Blood Loss, Surgic

2019
The effects of red blood cell preparation method on in vitro markers of red blood cell aging and inflammatory response.
    Transfusion, 2013, Volume: 53, Issue:12

    Topics: 2,3-Diphosphoglycerate; Blood Preservation; Cell-Derived Microparticles; Cells, Cultured; Erythrocyt

2013
Effect of transient warming of red blood cells for up to 24 h: in vitro characteristics in CPD/saline-adenine-glucose-mannitol environment.
    Vox sanguinis, 2014, Volume: 106, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Blood Preservation; Environmental Exposure; Erythrocytes; Glucose;

2014
Red blood cell in vitro quality and function is maintained after S-303 pathogen inactivation treatment.
    Transfusion, 2014, Volume: 54, Issue:7

    Topics: 2,3-Diphosphoglycerate; Acridines; Adenosine Triphosphate; Alkylating Agents; Blood Preservation; Bl

2014
A quality monitoring program for red blood cell components: in vitro quality indicators before and after implementation of semiautomated processing.
    Transfusion, 2014, Volume: 54, Issue:10

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Automation, Laboratory; Blood Banks; Blood Component

2014
Effects of four additive solutions on canine leukoreduced red cell concentrate quality during storage.
    Veterinary clinical pathology, 2014, Volume: 43, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Animals; Blood Preservation; Cell Survival;

2014
The effects of an overnight holding of whole blood at room temperature on haemoglobin modification and in vitro markers of red blood cell aging.
    Vox sanguinis, 2015, Volume: 108, Issue:4

    Topics: 2,3-Diphosphoglycerate; Blood Preservation; Erythrocyte Aging; Erythrocytes; Hemoglobins; Hemolysis;

2015
Effect of propolis on erythrocyte rheology in experimental mercury intoxication in rats.
    Environmental science and pollution research international, 2015, Volume: 22, Issue:16

    Topics: 2,3-Diphosphoglycerate; Animals; Erythrocytes; Hemolysis; Injections, Intraperitoneal; Leukocyte Cou

2015
Ex vivo encapsulation of dexamethasone sodium phosphate into human autologous erythrocytes using fully automated biomedical equipment.
    International journal of pharmaceutics, 2017, Jan-30, Volume: 517, Issue:1-2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Ataxia Telangiectasia; Automation; Case-Control Stud

2017
Storage of red blood cells in a novel polyolefin blood container: a pilot in vitro study.
    Vox sanguinis, 2017, Volume: 112, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Adult; Aged; Blood Glucose; Blood Preservation; Erythrocyte Count;

2017
Critical re-appraisal of blood component quality after overnight hold of whole blood outside current room temperature limits.
    Vox sanguinis, 2017, Volume: 112, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Platelets; Blood Preservation; Erythrocytes; H

2017
The effect of storing whole blood at 22 degrees C for up to 24 hours with and without rapid cooling on the quality of red cell concentrates and fresh-frozen plasma.
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Banks; Blood Preservation; Blood Proteins; Col

2008
An improved red blood cell additive solution maintains 2,3-diphosphoglycerate and adenosine triphosphate levels by an enhancing effect on phosphofructokinase activity during cold storage.
    Transfusion, 2010, Volume: 50, Issue:11

    Topics: 2,3-Diphosphoglycerate; Adenosine; Adenosine Triphosphate; Blood Preservation; Cryopreservation; Ery

2010
Influence of irradiation on in vitro red-blood-cell (RBC) storage variables of leucoreduced RBCs in additive solution PAGGS-M.
    Vox sanguinis, 2011, Volume: 101, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Blood Cell Count; Blood Preservation; Eryth

2011
Characteristics of prion-filtered red cells suspended in pathogen-inactivated plasma (MB treated or solvent-detergent treated) for neonatal exchange transfusion.
    Vox sanguinis, 2011, Volume: 101, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; alpha-2-Antiplasmin; Blood Preservation; Blood Prote

2011
Effect of rate and delay of cooling during initial cooling process: in vitro effect on red cells.
    Vox sanguinis, 2011, Volume: 101, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Preservation; Cold Temperature; Erythrocytes;

2011
Evaluation of the properties of components prepared and stored after holding of whole blood units for 8 and 24 hours at ambient temperature.
    Transfusion, 2011, Volume: 51 Suppl 1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Coagulation Factors; Blood Component Removal;

2011
Red cell concentrate storage and transport temperature.
    Transfusion medicine (Oxford, England), 2011, Volume: 21, Issue:5

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Preservation; Erythrocytes; Hemolysis; Humans;

2011
Centrifugation after irradiation of red blood cells does not accelerate haemolysis.
    Clinical laboratory, 2011, Volume: 57, Issue:7-8

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Glucose; Blood Preservation; Blood Transfusion

2011
Effects of helicopter transport on red blood cell components.
    Blood transfusion = Trasfusione del sangue, 2012, Volume: 10, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Aircraft; Blood Preservation; Erythrocyte Transfusio

2012
The 30 minute rule for red blood cells: in vitro quality assessment after repeated exposure to 30°C.
    Transfusion, 2013, Volume: 53, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Banks; Blood Preservation; Blood Specimen Coll

2013
Alkaline CPD and the preservation of RBC 2,3-DPG.
    Transfusion, 2002, Volume: 42, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Blood Preservation; Cell Survival; Citrates;

2002
Improved maintenance of 2,3 DPG and ATP in RBCs stored in a modified additive solution.
    Transfusion, 2002, Volume: 42, Issue:7

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Preservation; Erythrocytes; Hematocrit; Hemoly

2002
Twelve-week RBC storage.
    Transfusion, 2003, Volume: 43, Issue:7

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Donors; Blood Preservation; Erythrocyte Transf

2003
Interlaboratory comparison of red-cell ATP, 2,3-diphosphoglycerate and haemolysis measurements.
    Vox sanguinis, 2005, Volume: 89, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Biomarkers; Blood Preservation; Erythrocyte Aging; E

2005
Is it time to focus on preserving the functionality of red blood cells during storage?
    Transfusion, 2006, Volume: 46, Issue:9

    Topics: 2,3-Diphosphoglycerate; Blood Preservation; Cell Survival; Erythrocyte Membrane; Erythrocytes; Gluco

2006
Storage of red blood cells with improved maintenance of 2,3-bisphosphoglycerate.
    Transfusion, 2006, Volume: 46, Issue:9

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anticoagulants; Blood Preservation; Citrates; Erythr

2006
Storage of equine red blood cells as a concentrate.
    Veterinary journal (London, England : 1997), 2008, Volume: 176, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Blood Preservation; Erythrocytes; Hemolysis

2008
The effects of preserved red blood cells on the severe adverse events observed in patients infused with hemoglobin based oxygen carriers.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2008, Volume: 36, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Anemia; Blood Preservation; Blood Substitut

2008
Prolonged maintenance of 2,3-diphosphoglycerate acid and adenosine triphosphate in red blood cells during storage.
    Transfusion, 2008, Volume: 48, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Preservation; Cell Shape; Erythrocytes; Hemoly

2008
Molecular aspects of embryonic mouse haemoglobin ontogeny.
    The Biochemical journal, 1983, Nov-01, Volume: 215, Issue:2

    Topics: 2,3-Diphosphoglycerate; Animals; Chromatography, Ion Exchange; Diphosphoglyceric Acids; Fetal Hemogl

1983
Isoosmotic sucrose, adenine, inosine media for preservation of blood.
    Biomedica biochimica acta, 1983, Volume: 42, Issue:5

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Blood Preservation; Diphosphoglyceric Acids

1983
Dehydrated hereditary stomatocytosis--a report of two families and a review of the literature.
    Pathology, 1984, Volume: 16, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adult; Anemia, Hemolytic, Congenital; Anemia, Hemolytic, Congenital Nonspher

1984
Storage of red cell concentrates in CPD-A2 for 42 and 49 days.
    The Journal of laboratory and clinical medicine, 1983, Volume: 102, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Blood Preservation; Citrates; Diphosphoglyc

1983
Cryopreservation of cyanate-treated sickle erythrocytes.
    Cryobiology, 1982, Volume: 19, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Sickle Cell; Blood Preservation; Cyanates; D

1982
Clinical problems in the use of blood and blood substitutes.
    Surgery annual, 1982, Volume: 14

    Topics: 2,3-Diphosphoglycerate; Blood; Blood Substitutes; Blood Transfusion, Autologous; Communicable Diseas

1982
Half-strength citrate CPD and new additive solutions for improved blood preservation. I. Studies of six experimental solutions.
    Transfusion medicine (Oxford, England), 1993, Volume: 3, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine Nucleotides; Adenosine Triphosphate; Anticoagulants; Blood Preservat

1993
Half-strength citrate CPD combined with a new additive solution for improved storage of red blood cells suitable for clinical use.
    Vox sanguinis, 1993, Volume: 65, Issue:4

    Topics: 2,3-Diphosphoglycerate; Blood Donors; Blood Preservation; Citrates; Diphosphoglyceric Acids; Erythro

1993
Red cell alterations associated with virucidal methylene blue phototreatment.
    Transfusion, 1993, Volume: 33, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antiviral Agents; Blood Preservation; Dipho

1993
Influence of ozone on haemoglobin oxygen affinity in type-2 diabetic patients with peripheral vascular disease: in vitro studies.
    Diabete & metabolisme, 1995, Volume: 21, Issue:4

    Topics: 2,3-Diphosphoglycerate; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diph

1995
Physiological response to experimentally induced anemia in rats: a comparative study.
    Laboratory animal science, 1995, Volume: 45, Issue:5

    Topics: 2,3-Diphosphoglycerate; Anemia; Animals; Bone Marrow; Diphosphoglyceric Acids; Disease Models, Anima

1995
Mechanisms of hemolysate-induced [Ca2+]i elevation in cerebral smooth muscle cells.
    The American journal of physiology, 1995, Volume: 269, Issue:6 Pt 2

    Topics: 2,3-Diphosphoglycerate; Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Cytosol; Diphosp

1995
Physical determinants of intermembrane protein transfer.
    Biochemistry, 1996, Apr-02, Volume: 35, Issue:13

    Topics: 2,3-Diphosphoglycerate; Adult; Anion Exchange Protein 1, Erythrocyte; Autoradiography; Calcium; Carb

1996
[Effect of whole blood preparation and leukocyte filtration on storage of erythrocyte concentrates over 42 days].
    Beitrage zur Infusionstherapie und Transfusionsmedizin = Contributions to infusion therapy and transfusion medicine, 1997, Volume: 34

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Preservation; Erythrocyte Transfusion; Filtrat

1997
Intracellular hemoglobin S polymerization and the clinical severity of sickle cell anemia.
    Blood, 1998, Mar-01, Volume: 91, Issue:5

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Anemia, Sickle Cell; Erythrocyte Indices; Erythrocytes; F

1998
Improved blood preservation with 0.5CPD erythro-sol. Coagulation factor VIII activity and erythrocyte quality after delayed separation of blood.
    Vox sanguinis, 1998, Volume: 74, Issue:3

    Topics: 2,3-Diphosphoglycerate; Blood Preservation; Cell Separation; Citric Acid; Cold Temperature; Compleme

1998
Preservation of red cell properties after virucidal phototreatment with dimethylmethylene blue.
    Transfusion, 1998, Volume: 38, Issue:8

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Preservation; Diarrhea Viruses, Bovine Viral;

1998
Seroconversion of type B to O erythrocytes using recombinant Glycine max alpha-D-galactosidase.
    Biochemistry and molecular biology international, 1998, Volume: 46, Issue:1

    Topics: 2,3-Diphosphoglycerate; ABO Blood-Group System; Adenosine Triphosphate; alpha-Galactosidase; Choline

1998
Decreased hemolysis and lipid peroxidation in blood during storage in the presence of nicotinic acid.
    Vox sanguinis, 1999, Volume: 76, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Blood Preservation; Citrates; Diethylhexyl

1999
The effects of aged garlic extract on lipid peroxidation and the deformability of erythrocytes.
    The Journal of nutrition, 2001, Volume: 131, Issue:3s

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antioxidants; Cells, Cultured; Dose-Respons

2001
24-hour 51Cr post-transfusion survival, 51Cr life span and haemolysis of red blood cells stored at 4 degrees C for 56 days in AS-3.
    Vox sanguinis, 2001, Volume: 80, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenosine Triphosphate; Adult; Anticoagulants; Blood Component Remo

2001
Process for the preparation of pathogen-inactivated RBC concentrates by using PEN110 chemistry: preclinical studies.
    Transfusion, 2002, Volume: 42, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antigens, Surface; Aziridines; Blood Donors

2002
Prestorage WBC filtration of RBC units with soft-shell filters: filtration performance and impact on RBCs during storage for 42 days.
    Transfusion, 2002, Volume: 42, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Component Removal; Blood Preservation; Erythro

2002
Influence of the cryoprotective agents glycerol and hydroxyethyl starch on red blood cell ATP and 2,3-diphosphoglyceric acid levels.
    Vox sanguinis, 1992, Volume: 62, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Blood Preservation; Cryoprotective Agents; Di

1992
Studies in red blood cell preservation. 5. Determining the limiting concentrations of NH4Cl and Na2HPO4 needed to maintain red blood cell ATP during storage.
    Vox sanguinis, 1992, Volume: 62, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Ammonia; Ammonium Chloride; Blood Preservation; Diph

1992
[Improving the quality of washed and buffy coat-free erythrocyte concentrates].
    Folia haematologica (Leipzig, Germany : 1928), 1990, Volume: 117, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Cell Count; Blood Preservation; Cell Separatio

1990
Storage of saline-adenine-glucose-mannitol-suspended red cells in a new plastic container: polyvinylchloride plasticized with butyryl-n-trihexyl-citrate.
    Transfusion, 1991, Volume: 31, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenine; Adenine Nucleotides; Adenosine Triphosphate; Blood Glucose; Blood P

1991
Biochemical changes in rat erythrocytes caused by ethylene oxide exposure.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 15, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Macrocytic; Animals; Diphosphoglyceric Acids

1990
Factors influencing the formation of methemoglobin in desferrioxamine loaded erythrocytes.
    Biomedica biochimica acta, 1990, Volume: 49, Issue:2-3

    Topics: 2,3-Diphosphoglycerate; Deferoxamine; Diphosphoglyceric Acids; Erythrocytes; Hemolysis; Humans; Kine

1990
[Viability of human red blood cells preserved for 35 days after leukocyte depletion (in vitro study)].
    Revue francaise de transfusion et d'hemobiologie : bulletin de la Societe nationale de transfusion sanguine, 1989, Volume: 32, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Component Removal; Blood Glucose; Blood Preser

1989
Activation by calcium of AMP deaminase from the human red cell.
    FEBS letters, 1989, Feb-27, Volume: 244, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; AMP Deaminase; Calcium; Diphosphoglyceric Acids; Enz

1989
The bottom and top system: a new technique for blood component preparation and storage.
    Vox sanguinis, 1988, Volume: 55, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adenosine Monophosphate; Blood Cell Count; Blood Glucose; Blood Preservation

1988
[Functional nonequivalency of the erythrocytes in donor blood in relation to their acid resistance].
    Gematologiia i transfuziologiia, 1988, Volume: 33, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Blood Donors; Blood Viscosity; Diphosphoglyceric Aci

1988
Pressure increases oxygen affinity of whole blood and erythrocyte suspensions.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 61, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adult; Diphosphoglyceric Acids; Erythrocytes; Hemoglobins; Hemolysis; Humans

1986