2,3-diphosphoglycerate has been researched along with Hemoglobinopathies in 7 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Hemoglobinopathies: A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The term familial and congenital polycythemia encompasses a heterogeneous group of disorders with the common characteristic of an absolute increased red cell mass since birth and/or similar phenotype also present in relatives." | 2.39 | "Benign erythrocytosis" and other familial and congenital polycythemias. ( Prchal, JT; Sokol, L, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vinciguerra, M | 1 |
| Passarello, C | 1 |
| Cassarà, F | 1 |
| Leto, F | 1 |
| Cannata, M | 1 |
| Crivello, A | 1 |
| Di Salvo, V | 1 |
| Maggio, A | 1 |
| Giambona, A | 1 |
| Prchal, JT | 2 |
| Pastore, YD | 1 |
| Benjamin, D | 1 |
| Tabak, M | 1 |
| Avissar, N | 1 |
| Spitzer, SA | 1 |
| Pinkhas, J | 1 |
| Sokol, L | 1 |
| Larson, PJ | 1 |
| Friedman, DF | 1 |
| Reilly, MP | 1 |
| Kattamis, AC | 1 |
| Asakura, T | 1 |
| Fortina, P | 1 |
| Cohen, AR | 1 |
| Kim, HC | 1 |
| Manno, CS | 1 |
| Como, PF | 1 |
| Hocking, DR | 1 |
| Swinton, GW | 1 |
| Trent, RJ | 1 |
| Holland, RA | 1 |
| Tibben, EA | 1 |
| Wilkinson, T | 1 |
| Kronenberg, H | 1 |
| Kister, J | 1 |
| Barbadjian, J | 1 |
| Blouquit, Y | 1 |
| Bohn, B | 1 |
| Galacteros, F | 1 |
| Poyart, C | 1 |
2 reviews available for 2,3-diphosphoglycerate and Hemoglobinopathies
| Article | Year |
|---|---|
Erythropoietin and erythropoiesis: polycythemias due to disruption of oxygen homeostasis.
Topics: 2,3-Diphosphoglycerate; Bisphosphoglycerate Mutase; Erythropoiesis; Erythropoietin; Gene Expression | 2004 |
"Benign erythrocytosis" and other familial and congenital polycythemias.
Topics: 2,3-Diphosphoglycerate; Diphosphoglyceric Acids; Erythropoiesis; Erythropoietin; Hemoglobinopathies; | 1996 |
5 other studies available for 2,3-diphosphoglycerate and Hemoglobinopathies
| Article | Year |
|---|---|
Hb San Cataldo [β144(HC1)Lys→Thr; HBB: C.434A > C]: A New Hemoglobin Variant with Increased Affinity for Oxygen.
Topics: 2,3-Diphosphoglycerate; Diagnosis, Differential; Female; Hemoglobinopathies; Hemoglobins, Abnormal; | 2016 |
Oxygen affinity of hemoglobin in polycythemia of undetermined etiology.
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Diphosphoglyceric Acids; Female; Hemoglobinopathies; Hemoglobin | 1980 |
The presurgical management with erythrocytapheresis of a patient with a high-oxygen-affinity, unstable Hb variant (Hb Bryn Mawr).
Topics: 2,3-Diphosphoglycerate; Anemia, Hemolytic; Blood Component Removal; Child; Cholelithiasis; Diphospho | 1997 |
Hb Geelong [beta 139(H17)Asn----Asp].
Topics: 2,3-Diphosphoglycerate; Adult; Amino Acid Sequence; Diphosphoglyceric Acids; Female; Globins; Hemogl | 1991 |
Inhibition of oxygen-linked anion binding in Hb Camperdown [alpha 2 beta 2(104)(G6)Arg----Ser].
Topics: 2,3-Diphosphoglycerate; Anions; Chlorides; Diphosphoglyceric Acids; Hemoglobinopathies; Hemoglobins, | 1989 |