2,3-diphosphoglycerate has been researched along with Heart Failure in 7 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the importance of 2,3-diphosphoglycerate (2,3-DPG) and oxygen-haemoglobin binding to oxygen transport in patients with congestive heart failure." | 3.68 | Importance of oxygen-haemoglobin binding to oxygen transport in congestive heart failure. ( Bersin, RM; Chatterjee, K; DeMarco, T; Khorrami, P; Klinski, C; Kwasman, M; Lau, D; Tanaka, K; Wolfe, C, 1993) |
| "Blood gaseous composition, mechanisms controlling hemoglobin affinity to oxygen and hemoglobin effects of a single captopril dose were assessed in 124 patients with chronic heart failure (CHF)." | 3.67 | [Hemoglobin affinity to oxygen and its correction with captopril in chronic cardiac insufficiency]. ( Blistanova, LS; Griaznov, VV; Kukes, VG, 1989) |
| "In 30 patients with severe congestive heart failure, arterial, mixed venous, and coronary sinus venous blood concentrations of 2,3-DPG were measured and systemic output and coronary sinus blood flow were measured by a thermodilution technique." | 1.29 | Importance of oxygen-haemoglobin binding to oxygen transport in congestive heart failure. ( Bersin, RM; Chatterjee, K; DeMarco, T; Khorrami, P; Klinski, C; Kwasman, M; Lau, D; Tanaka, K; Wolfe, C, 1993) |
| "CHF-associated hypoxemia was shown to be mixed, with the circulatory component prevailing." | 1.28 | [Hemoglobin affinity to oxygen and its correction with captopril in chronic cardiac insufficiency]. ( Blistanova, LS; Griaznov, VV; Kukes, VG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (42.86) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Deryugina, AV | 1 |
| Danilova, DA | 1 |
| Skokova, AA | 1 |
| Brichkin, YD | 1 |
| Pichugin, VV | 1 |
| Medvedev, AP | 1 |
| Ryazanov, MV | 1 |
| Fedorov, SA | 1 |
| Takagi, Y | 1 |
| Botas, L | 1 |
| Freitas, JP | 1 |
| Barroca, JP | 1 |
| Laginha, T | 1 |
| Martins e Silva, J | 1 |
| Bersin, RM | 1 |
| Kwasman, M | 1 |
| Lau, D | 1 |
| Klinski, C | 1 |
| Tanaka, K | 1 |
| Khorrami, P | 1 |
| DeMarco, T | 1 |
| Wolfe, C | 1 |
| Chatterjee, K | 1 |
| Sisetskiĭ, AP | 1 |
| Artiuk, VP | 1 |
| Sakharchuk, II | 1 |
| Starodub, NF | 1 |
| Kukes, VG | 1 |
| Griaznov, VV | 1 |
| Blistanova, LS | 1 |
| Taniguchi, N | 1 |
| Yamauchi, K | 1 |
| Furui, H | 1 |
| Koide, M | 1 |
| Tsuzuki, M | 1 |
| Takami, K | 1 |
| Kondo, T | 1 |
| Yokota, M | 1 |
| Hayashi, H | 1 |
| Sotobata, I | 1 |
1 review available for 2,3-diphosphoglycerate and Heart Failure
| Article | Year |
|---|---|
[2,3-Diphosphoglycerate (2,3-DPG)].
Topics: 2,3-Diphosphoglycerate; Anemia; Biomarkers; Cyanosis; Diabetic Ketoacidosis; Heart Failure; Hematolo | 2004 |
6 other studies available for 2,3-diphosphoglycerate and Heart Failure
| Article | Year |
|---|---|
Dynamics of Metabolic and Oxidative Parameters of Erythrocytes during Treatment of Chronic Heart Failure with Molecular Hydrogen.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Antioxidants; Catalase; Erythrocytes; Heart Failure; | 2022 |
[Peripheral tissue oxygenation in patients with congestive heart failure].
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Diphosphoglyceric Acids; Erythrocytes; Female; Heart Failure; H | 1983 |
Importance of oxygen-haemoglobin binding to oxygen transport in congestive heart failure.
Topics: 2,3-Diphosphoglycerate; Biological Transport; Diphosphoglyceric Acids; Heart Failure; Hemoglobins; H | 1993 |
[The phosphate and methemoglobin content of the erythrocytes in patients with ischemic heart disease].
Topics: 2,3-Diphosphoglycerate; Chronic Disease; Coronary Disease; Diphosphoglyceric Acids; Drug Therapy, Co | 1991 |
[Hemoglobin affinity to oxygen and its correction with captopril in chronic cardiac insufficiency].
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Captopril; Carbon Dioxide; Chronic Disease; Diphosphoglyceric A | 1989 |
[Studies on hemoglobin oxygen dissociation in patients with congestive heart failure].
Topics: 2,3-Diphosphoglycerate; Diphosphoglyceric Acids; Female; Heart Failure; Hemoglobins; Humans; Male; O | 1985 |