2,3-diphosphoglycerate has been researched along with Fatigue Syndrome, Chronic in 3 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Fatigue Syndrome, Chronic: A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Richards, RS | 3 |
| Wang, L | 1 |
| Jelinek, H | 1 |
| Roberts, TK | 2 |
| McGregor, NR | 2 |
| Dunstan, RH | 2 |
| Butt, HL | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of High Dose Vitamin C Parenteral Supplement on Amelioration of Fatigue in Company Workers After Work: A Double-Blind, Randomized Controlled Trial[NCT00633581] | Phase 2/Phase 3 | 150 participants (Actual) | Interventional | 2008-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for 2,3-diphosphoglycerate and Fatigue Syndrome, Chronic
| Article | Year |
|---|---|
Erythrocyte oxidative damage in chronic fatigue syndrome.
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Child; Erythrocyte Deformability; Erythrocytes; Fat | 2007 |
Blood parameters indicative of oxidative stress are associated with symptom expression in chronic fatigue syndrome.
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Child; Fatigue Syndrome, Chronic; Female; Hematolog | 2000 |
Free radicals in chronic fatigue syndrome: cause or effect?
Topics: 2,3-Diphosphoglycerate; Arthritis, Rheumatoid; Erythrocytes; Fatigue Syndrome, Chronic; Female; Free | 2000 |