2,3-diphosphoglycerate has been researched along with Disease Models, Animal in 10 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To induce anemia experimentally in rats to provide a hematocrit of 30 to 35% and provide data about the physiologic response to anemia during induction and after it is established, two methods were selected: the application of repetitive doses of phenylhydrazine and bleeding." | 3.69 | Physiological response to experimentally induced anemia in rats: a comparative study. ( Alvarez, AI; Diez, C; Fernández-Rojo, F; Prieto, JG; Redondo, PA, 1995) |
| "Hypotension due to hemorrhagic shock was induced by removing 40 ml." | 1.29 | [The function of red blood cells during experimental hemorrhagic and endotoxic shock]. ( Matsumoto, Y, 1995) |
| "Endotoxin shock was induced using a 30-minute continuous infusion of Escherichia coli 055 endotoxin 5 mg." | 1.29 | [The function of red blood cells during experimental hemorrhagic and endotoxic shock]. ( Matsumoto, Y, 1995) |
| "2,3-Diphosphoglycerate was induced only during the recovery phase of the study and corresponded to a gradual response to hypoxia." | 1.29 | Physiological response to experimentally induced anemia in rats: a comparative study. ( Alvarez, AI; Diez, C; Fernández-Rojo, F; Prieto, JG; Redondo, PA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Quezado, ZMN | 1 |
| Kamimura, S | 1 |
| Smith, M | 1 |
| Wang, X | 1 |
| Heaven, MR | 1 |
| Jana, S | 1 |
| Vogel, S | 1 |
| Zerfas, P | 1 |
| Combs, CA | 1 |
| Almeida, LEF | 1 |
| Li, Q | 1 |
| Quezado, M | 1 |
| Horkayne-Szakaly, I | 1 |
| Kosinski, PA | 1 |
| Yu, S | 1 |
| Kapadnis, U | 1 |
| Kung, C | 1 |
| Dang, L | 1 |
| Wakim, P | 1 |
| Eaton, WA | 1 |
| Alayash, AI | 1 |
| Thein, SL | 1 |
| Wang, L | 1 |
| Ren, C | 1 |
| Li, Y | 1 |
| Gao, C | 1 |
| Li, N | 1 |
| Li, H | 1 |
| Wu, D | 1 |
| He, X | 1 |
| Xia, C | 1 |
| Ji, X | 1 |
| Bateman, RM | 1 |
| Sharpe, MD | 1 |
| Singer, M | 1 |
| Ellis, CG | 1 |
| Zhao, ZG | 1 |
| Zhu, HX | 1 |
| Zhang, LM | 1 |
| Zhang, YP | 1 |
| Niu, CY | 1 |
| Agar, NS | 1 |
| Suzuki, T | 1 |
| Roberts, J | 1 |
| Evans, JV | 1 |
| Woodson, RD | 1 |
| Matsumoto, Y | 1 |
| Redondo, PA | 1 |
| Alvarez, AI | 1 |
| Diez, C | 1 |
| Fernández-Rojo, F | 1 |
| Prieto, JG | 1 |
| Hotta, N | 1 |
| Koh, N | 1 |
| Sakakibara, F | 1 |
| Nakamura, J | 1 |
| Hamada, Y | 1 |
| Hara, T | 1 |
| Mori, K | 1 |
| Naruse, K | 1 |
| Fukasawa, H | 1 |
| Kakuta, H | 1 |
| Sakamoto, N | 1 |
| Fabry, ME | 1 |
| Suzuka, SM | 1 |
| Weinberg, RS | 1 |
| Lawrence, C | 1 |
| Factor, SM | 1 |
| Gilman, JG | 1 |
| Costantini, F | 1 |
| Nagel, RL | 1 |
1 review available for 2,3-diphosphoglycerate and Disease Models, Animal
| Article | Year |
|---|---|
The Effect of Sepsis on the Erythrocyte.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antioxidants; Calcium; Cell Shape; Cell Siz | 2017 |
9 other studies available for 2,3-diphosphoglycerate and Disease Models, Animal
| Article | Year |
|---|---|
Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Sickle Cell; Animals; Disease Models, Animal | 2022 |
Remote ischemic conditioning enhances oxygen supply to ischemic brain tissue in a mouse model of stroke: Role of elevated 2,3-biphosphoglycerate in erythrocytes.
Topics: 2,3-Diphosphoglycerate; Animals; Brain; Brain Ischemia; Disease Models, Animal; Erythrocytes; Ischem | 2021 |
Mesenteric lymph drainage alleviates acute kidney injury induced by hemorrhagic shock without resuscitation.
Topics: 2,3-Diphosphoglycerate; Acute Kidney Injury; Animals; Biomarkers; Disease Models, Animal; Drainage; | 2014 |
Effect of anaemia on red cell metabolism in cattle.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia; Animals; Cattle; Diphosphoglyceric Acids; Di | 1983 |
Importance of 2,3 DPG in banked blood: new data in animal models.
Topics: 2,3-Diphosphoglycerate; Animals; Biological Transport; Blood Flow Velocity; Blood Preservation; Card | 1982 |
[The function of red blood cells during experimental hemorrhagic and endotoxic shock].
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Diphosphoglyceric Acids; Disease Models, An | 1995 |
Physiological response to experimentally induced anemia in rats: a comparative study.
Topics: 2,3-Diphosphoglycerate; Anemia; Animals; Bone Marrow; Diphosphoglyceric Acids; Disease Models, Anima | 1995 |
Nerve function and blood flow in Otsuka Long-Evans Tokushima Fatty rats with sucrose feeding: effect of an anticoagulant.
Topics: 2,3-Diphosphoglycerate; Alcohols; Animals; Anticoagulants; Blood Glucose; Body Weight; Carbohydrate | 1996 |
Second generation knockout sickle mice: the effect of HbF.
Topics: 2,3-Diphosphoglycerate; Age Factors; Anemia, Sickle Cell; Animals; Chromatography, High Pressure Liq | 2001 |