Page last updated: 2024-10-15

2,3-diphosphoglycerate and Diabetic Retinopathy

2,3-diphosphoglycerate has been researched along with Diabetic Retinopathy in 10 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.

Research Excerpts

ExcerptRelevanceReference
"The patient proved to have polycythemia, hemoglobin Kansas, and diabetes mellitus."1.28Hemoglobin Kansas found in a patient with polycythemia. ( Fujisawa, K; Fukuzawa, J; Hayashi, Y; Kawamura, Y; Miyají, T; Morita, K; Ohba, Y; Onodera, S; Sasaki, N; Yamazaki, N, 1992)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's4 (40.00)18.2507
2000's0 (0.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giral, P1
Rosenbaum, D1
Artioli, F1
Carapezzi, C1
Nuzzi, G1
Pedrazzoni, M1
Cucinotta, D1
Marani, L1
Ferretti, PG1
Nielsen, NV1
Ditzel, J1
Jensen, S1
Kjaergaard, JJ1
Hotta, N2
Koh, N2
Sakakibara, F2
Nakamura, J2
Hara, T2
Hamada, Y2
Fukasawa, H1
Kakuta, H1
Sakamoto, N1
Mori, K1
Nakashima, E1
Sasaki, H1
Kasama, N1
Inukai, S1
Morita, K1
Fukuzawa, J1
Onodera, S1
Kawamura, Y1
Sasaki, N1
Fujisawa, K1
Ohba, Y1
Miyají, T1
Hayashi, Y1
Yamazaki, N1
Zhou, ZG1
Wu, HW1
Chao, CS1
Hosaki, S1
Okamura, C1
Hagiwara, M1
Suzumori, K1
Shiina, S1
Uchimura, I1
Maezawa, H1
Zaretskaya, RB1
Trutneva, KV1
Tartakovskaya, AI1
Antonova, ES1
Gräfenstein, K1
Duchna, W1

Trials

1 trial available for 2,3-diphosphoglycerate and Diabetic Retinopathy

ArticleYear
The effect of etidronate disodium (EHDP) on retinopathy in insulin-dependent diabetic patients.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1982, Volume: 219, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adult; Blood Glucose; Diabetic Retinopathy; Diphosphoglyceric Acids; Double-

1982

Other Studies

9 other studies available for 2,3-diphosphoglycerate and Diabetic Retinopathy

ArticleYear
Retinopathy progression in type 2 diabetes.
    The New England journal of medicine, 2010, 11-25, Volume: 363, Issue:22

    Topics: 2,3-Diphosphoglycerate; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Fenofi

2010
[Relation between the metabolic state, tissue oxygenation and diabetic microangiopathy].
    Giornale di clinica medica, 1984, Volume: 65, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Blood Glucose; Cholesterol; Diabetic Retinopathy; Diphosphoglyceric A

1984
Effect of an aldose reductase inhibitor on abnormalities of electroretinogram and vascular factors in diabetic rats.
    European journal of pharmacology, 1997, May-12, Volume: 326, Issue:1

    Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Blood Glucose; Carbohydrate Metabolism; Diabete

1997
Electroretinogram in sucrose-fed diabetic rats treated with an aldose reductase inhibitor or an anticoagulant.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Anticoagulants; Blood Glucose; Body Weight; Cil

1997
Hemoglobin Kansas found in a patient with polycythemia.
    Annals of hematology, 1992, Volume: 65, Issue:5

    Topics: 2,3-Diphosphoglycerate; Cyanosis; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; D

1992
[Study on risk factors of tissue hypoxia in patients with diabetic retinopathy].
    Zhonghua nei ke za zhi, 1992, Volume: 30, Issue:10

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Cell Hypoxia; Diabetic Retinopathy; Diphosphoglycer

1992
[Study on erythrocyte oxygen dissociation activity in non-acidotic diabetic patients and their complications].
    Rinsho byori. The Japanese journal of clinical pathology, 1986, Volume: 34, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adult; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Diph

1986
Functional condition of the visual analyzer and oxygen metabolism kinetics in pregnant women with diabetes.
    Metabolic, pediatric, and systemic ophthalmology (New York, N.Y. : 1985), 1985, Volume: 8, Issue:2-3

    Topics: 2,3-Diphosphoglycerate; Diabetic Retinopathy; Diphosphoglyceric Acids; Erythrocytes; Female; Humans;

1985
[Relation between glycohemoglobin, hypoxia parameters and diabetic microangiopathy].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1985, Apr-15, Volume: 40, Issue:8

    Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Re

1985