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2,3-diphosphoglycerate and Diabetic Ketoacidosis

2,3-diphosphoglycerate has been researched along with Diabetic Ketoacidosis in 7 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Diabetic Ketoacidosis: A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by KETOSIS; DEHYDRATION; and depressed consciousness leading to COMA.

Research Excerpts

ExcerptRelevanceReference
"Measurements were made of lactate, pyruvate and 2,3-diphosphoglycerate in 69 children admitted to the hospital in a state of diabetic ketoacidosis of different intensity."3.68[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus]. ( Baturin, AA; Marchenko, LF; Terent'eva, EA, 1991)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takagi, Y1
Fisher, JN1
Kitabchi, AE1
Rodríguez Cuartero, A1
Rodríguez Cuartero, F1
Pérez Blanco, F1
Núñez Carril, J1
Mora Lara, RJ1
Clerbaux, T1
Detry, B1
Reynaert, M1
Kreuzer, F1
Frans, A1
Marchenko, LF1
Baturin, AA1
Terent'eva, EA1
Vázquez, C1
Valdivielso, L1
Cordido, F1
Suárez, C1
González, C1
de la Morena, E1
Herrera Pombo, JL1
Ryall, RG1
Ellis, RH1
Wenzel, AK1

Reviews

1 review available for 2,3-diphosphoglycerate and Diabetic Ketoacidosis

ArticleYear
[2,3-Diphosphoglycerate (2,3-DPG)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 12

    Topics: 2,3-Diphosphoglycerate; Anemia; Biomarkers; Cyanosis; Diabetic Ketoacidosis; Heart Failure; Hematolo

2004

Trials

1 trial available for 2,3-diphosphoglycerate and Diabetic Ketoacidosis

ArticleYear
A randomized study of phosphate therapy in the treatment of diabetic ketoacidosis.
    The Journal of clinical endocrinology and metabolism, 1983, Volume: 57, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Calcium; Diabetic Ketoacidosis; Diphosphoglyceric Acids; Erythrocytes

1983

Other Studies

5 other studies available for 2,3-diphosphoglycerate and Diabetic Ketoacidosis

ArticleYear
[Behavior of 2,3-diphosphoglycerate in diabetes mellitus].
    Revista clinica espanola, 1982, Apr-15, Volume: 165, Issue:1

    Topics: 2,3-Diphosphoglycerate; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Coma; Diabetic Ketoacidos

1982
Reestimation of the effects of inorganic phosphates on the equilibrium between oxygen and hemoglobin.
    Intensive care medicine, 1992, Volume: 18, Issue:4

    Topics: 2,3-Diphosphoglycerate; Blood Gas Analysis; Diabetic Ketoacidosis; Diphosphoglyceric Acids; Evaluati

1992
[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus].
    Pediatriia, 1991, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Com

1991
[2,3 diphosphoglycerate and diabetes mellitus in various metabolic situations].
    Revista clinica espanola, 1985, Volume: 176, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Analysis of Variance; Blood Glucose; Diabetes Melli

1985
Insensitivity of erythrocyte 2,3-bisphosphoglycerate to changes in extracellular phosphate concentration in vitro.
    Annals of clinical biochemistry, 1985, Volume: 22 ( Pt 3)

    Topics: 2,3-Diphosphoglycerate; Diabetic Ketoacidosis; Diphosphoglyceric Acids; Erythrocytes; Humans; Hydrog

1985