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2,3-diphosphoglycerate and Diabetes Mellitus, Type 2

2,3-diphosphoglycerate has been researched along with Diabetes Mellitus, Type 2 in 14 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19905 (35.71)18.7374
1990's5 (35.71)18.2507
2000's3 (21.43)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giral, P1
Rosenbaum, D1
Castilho, EM1
Glass, ML1
Manço, JC1
Beder, I1
Mataseje, A1
Kittova, M1
Carsky, J1
Fischer, V1
Tirelli, A1
Misso, L1
Coppola, L2
Scognamiglio, G1
Varano, R1
Scognamiglio, C1
Torella, R1
Stufano, N1
Altomare, E1
Conese, A1
Sabbà, C1
Carbone, P1
Vendemiale, G1
Palasciano, G1
Albano, O1
Resnick, LM1
Gupta, RK1
Barbagallo, M1
Laragh, JH1
Giunta, R1
Verrazzo, G1
Luongo, C1
Sammartino, A1
Vicario, C1
Giugliano, D1
Hotta, N3
Koh, N3
Sakakibara, F3
Nakamura, J3
Hamada, Y3
Hara, T3
Mori, K3
Naruse, K2
Fukasawa, H1
Kakuta, H1
Sakamoto, N1
Iino, K1
Yoshinari, M1
Doi, Y1
Shinohara, N1
Iwase, M1
Fujishima, M1
Nakashima, E2
Sasaki, H1
Kasama, N1
Inukai, S1
Wakao, T1
Kamijo, M1
Zhou, ZG1
Wu, HW1
Chao, CS1
Kerényi, Z1
Tamás, G1
Vargha, P1
Galenok, VA1
Grinshpun, MN1
Dikker, VE1

Trials

1 trial available for 2,3-diphosphoglycerate and Diabetes Mellitus, Type 2

ArticleYear
Reduced tissue oxygenation and its reversibility by glycemic control in diabetic patients.
    Diabetes research and clinical practice, 1997, Volume: 34, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Aged, 80 and over; Blood Gas Monitoring, Transcutan

1997

Other Studies

13 other studies available for 2,3-diphosphoglycerate and Diabetes Mellitus, Type 2

ArticleYear
Retinopathy progression in type 2 diabetes.
    The New England journal of medicine, 2010, 11-25, Volume: 363, Issue:22

    Topics: 2,3-Diphosphoglycerate; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; Fenofi

2010
The effects of 2,3-diphosphoglycerate, adenosine triphosphate, and glycosylated hemoglobin on the hemoglobin-oxygen affinity of diabetic patients.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2003, Volume: 36, Issue:6

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Case-Control Studies; Diabetes Mellitus

2003
2,3-diphosphoglycerate and oxygen supply of tissues in cardiosurgical diabetics.
    Bratislavske lekarske listy, 2005, Volume: 106, Issue:10

    Topics: 2,3-Diphosphoglycerate; Coronary Artery Bypass; Diabetes Mellitus, Type 2; Erythrocyte Count; Hemato

2005
[Changes in mean erythrocyte volume and 2,3-diphosphoglycerate in two groups of diabetic subjects].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Nov-30, Volume: 59, Issue:11

    Topics: 2,3-Diphosphoglycerate; Adult; Age Factors; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Di

1983
[2,3-diphosphoglycerate and glycosylated hemoglobin in diabetes mellitus].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Dec-30, Volume: 59, Issue:12

    Topics: 2,3-Diphosphoglycerate; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diphosphoglycer

1983
Is the higher incidence of ischemic disease in patients with hypertension and diabetes related to intracellular depletion of high energy metabolites?
    The American journal of the medical sciences, 1994, Volume: 307 Suppl 1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Diabetes Mellitus, Type 2; Diphosphoglyceric Acids;

1994
Influence of ozone on haemoglobin oxygen affinity in type-2 diabetic patients with peripheral vascular disease: in vitro studies.
    Diabete & metabolisme, 1995, Volume: 21, Issue:4

    Topics: 2,3-Diphosphoglycerate; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diph

1995
Nerve function and blood flow in Otsuka Long-Evans Tokushima Fatty rats with sucrose feeding: effect of an anticoagulant.
    European journal of pharmacology, 1996, Oct-17, Volume: 313, Issue:3

    Topics: 2,3-Diphosphoglycerate; Alcohols; Animals; Anticoagulants; Blood Glucose; Body Weight; Carbohydrate

1996
Electroretinogram in sucrose-fed diabetic rats treated with an aldose reductase inhibitor or an anticoagulant.
    The American journal of physiology, 1997, Volume: 273, Issue:5

    Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Anticoagulants; Blood Glucose; Body Weight; Cil

1997
Physiological and morphometric analyses of neuropathy in sucrose-fed OLETF rats.
    Diabetes research and clinical practice, 2001, Volume: 51, Issue:1

    Topics: 2,3-Diphosphoglycerate; Aldehyde Reductase; Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathie

2001
[Erythrocyte 2,3-diphosphoglycerate changes and the effect of phosphate supplement in diabetics].
    Zhonghua nei ke za zhi, 1988, Volume: 27, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Diabetes Mellitus, Type 2; Diphosphoglyceric Acids;

1988
[Diurnal shifts of 2,3-diphosphoglycerate in diabetics and healthy subjects].
    Orvosi hetilap, 1987, Jan-04, Volume: 128, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Circadian Rhythm; Diabetes Mellitus, Type 2; Diphosphoglyceric Acids;

1987
[Hemoglobin A1C and tissue oxygen balance in compensated diabetes mellitus].
    Klinicheskaia meditsina, 1987, Volume: 65, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dip

1987