2,3-diphosphoglycerate has been researched along with Diabetes Mellitus, Type 1 in 16 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diabetic pregnancy was associated with relative anemia, a significant increase in arterial pH, and hypocapnia." | 5.27 | Red cell 2,3-diphosphoglycerate and hemoglobin-oxygen affinity during diabetic pregnancy. ( Ditzel, J; Madsen, H, 1984) |
| "Measurements were made of lactate, pyruvate and 2,3-diphosphoglycerate in 69 children admitted to the hospital in a state of diabetic ketoacidosis of different intensity." | 3.68 | [Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus]. ( Baturin, AA; Marchenko, LF; Terent'eva, EA, 1991) |
| "Insulin-dependent diabetes mellitus (IDDM) is a common metabolic disease often complicated by a number of pathological conditions among which are haematological changes and alterations in blood cell function." | 1.31 | Some aspects of erythrocyte metabolism in insulin-treated diabetic dogs. ( Comazzi, S; Paltrinieri, S; Sartorelli, P; Spagnolo, V, 2002) |
| "Diabetic pregnancy was associated with relative anemia, a significant increase in arterial pH, and hypocapnia." | 1.27 | Red cell 2,3-diphosphoglycerate and hemoglobin-oxygen affinity during diabetic pregnancy. ( Ditzel, J; Madsen, H, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Castilho, EM | 1 |
| Glass, ML | 1 |
| Manço, JC | 1 |
| Pańkowska, E | 1 |
| Szypowska, A | 1 |
| Wysocka, M | 1 |
| Lipka, M | 1 |
| Madsen, H | 2 |
| Ditzel, J | 2 |
| Tirelli, A | 1 |
| Misso, L | 1 |
| Coppola, L | 1 |
| Scognamiglio, G | 1 |
| Varano, R | 1 |
| Scognamiglio, C | 1 |
| Torella, R | 1 |
| Stufano, N | 1 |
| Altomare, E | 1 |
| Conese, A | 1 |
| Sabbà, C | 1 |
| Carbone, P | 1 |
| Vendemiale, G | 1 |
| Palasciano, G | 1 |
| Albano, O | 1 |
| Pozza, G | 1 |
| Carandente, O | 1 |
| Roberts, AP | 2 |
| Story, CJ | 2 |
| Ryall, RG | 2 |
| Sitzmann, FC | 1 |
| Dockter, G | 1 |
| Comazzi, S | 1 |
| Paltrinieri, S | 1 |
| Spagnolo, V | 1 |
| Sartorelli, P | 1 |
| Marchenko, LF | 1 |
| Baturin, AA | 1 |
| Terent'eva, EA | 1 |
| Kerényi, Z | 1 |
| Tamás, G | 1 |
| Varga, P | 1 |
| Galenok, VA | 1 |
| Grinshpun, MN | 1 |
| Dikker, VE | 1 |
| Liu, XC | 1 |
| Huang, Z | 1 |
| Gräfenstein, K | 1 |
| Duchna, W | 1 |
16 other studies available for 2,3-diphosphoglycerate and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
The effects of 2,3-diphosphoglycerate, adenosine triphosphate, and glycosylated hemoglobin on the hemoglobin-oxygen affinity of diabetic patients.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Case-Control Studies; Diabetes Mellitus | 2003 |
[The role of 2,3-DPG in nerve conduction of children with type 1 diabetes].
Topics: 2,3-Diphosphoglycerate; Adolescent; Child; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Female; | 2005 |
Red cell 2,3-diphosphoglycerate and hemoglobin-oxygen affinity during diabetic pregnancy.
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Diabetes Mellitus, Type 1; Diphosphoglyceric Acids; Eryth | 1984 |
[Changes in mean erythrocyte volume and 2,3-diphosphoglycerate in two groups of diabetic subjects].
Topics: 2,3-Diphosphoglycerate; Adult; Age Factors; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Di | 1983 |
[2,3-diphosphoglycerate and glycosylated hemoglobin in diabetes mellitus].
Topics: 2,3-Diphosphoglycerate; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diphosphoglycer | 1983 |
[Erythrocyte changes in diabetes].
Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diabetes Mellitus, Type 1; Diphosphoglyceric Acids; Erythrocy | 1983 |
Erythrocyte 2,3-bisphosphoglycerate concentrations and haemoglobin glycosylation in normoxic Type 1 (insulin-dependent) diabetes mellitus.
Topics: 2,3-Diphosphoglycerate; Diabetes Mellitus, Type 1; Diphosphoglyceric Acids; Erythrocytes; Glycated H | 1984 |
Blood-oxygen transport in first trimester of diabetic pregnancy.
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Diphosphoglycer | 1984 |
[Erythrocyte enzymes and 2,3-diphosphoglycerate in juvenile diabetics].
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Child; Diabetes Mellitus, Type 1; Diphosphoglyceric Acids | 1982 |
Some aspects of erythrocyte metabolism in insulin-treated diabetic dogs.
Topics: 2,3-Diphosphoglycerate; Animals; Blood Chemical Analysis; Diabetes Mellitus, Type 1; Dog Diseases; D | 2002 |
[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus].
Topics: 2,3-Diphosphoglycerate; Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diabetic Com | 1991 |
[The effect of hypoglycemic episodes in diabetics on the 2,3-diphosphoglycerate content of erythrocytes].
Topics: 2,3-Diphosphoglycerate; Adult; Diabetes Mellitus, Type 1; Diphosphoglyceric Acids; Erythrocytes; Fem | 1987 |
[Hemoglobin A1C and tissue oxygen balance in compensated diabetes mellitus].
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dip | 1987 |
[Relation between 2,3-diphosphoglyceric acids and HbA1 in insulin-dependent diabetic children].
Topics: 2,3-Diphosphoglycerate; Adolescent; Child; Child, Preschool; Diabetes Mellitus, Type 1; Diphosphogly | 1985 |
Borderline maintenance of erythrocyte 2,3-diphosphoglycerate concentrations in normoxic type 1 (insulin dependent) diabetic subjects.
Topics: 2,3-Diphosphoglycerate; Adult; Diabetes Mellitus, Type 1; Diphosphoglyceric Acids; Erythrocytes; Gly | 1986 |
[Relation between glycohemoglobin, hypoxia parameters and diabetic microangiopathy].
Topics: 2,3-Diphosphoglycerate; Blood Glucose; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Diabetic Re | 1985 |