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2,3-diphosphoglycerate and Cystic Fibrosis

2,3-diphosphoglycerate has been researched along with Cystic Fibrosis in 3 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berghout, AG1
Bender, SW1
Wagener, JS1
McNeill, GC1
Taussig, LM1
Corrigan, JJ1
Lemen, R1
Vichinsky, EP1
Pennathur-Das, R1
Nickerson, B1
Minor, M1
Kleman, K1
Higashino, S1
Lubin, B1

Other Studies

3 other studies available for 2,3-diphosphoglycerate and Cystic Fibrosis

ArticleYear
Anion transport and 2,3-diphosphoglycerate in cystic fibrosis red blood cells.
    Pediatric research, 1984, Volume: 18, Issue:10

    Topics: 2,3-Diphosphoglycerate; Cell Membrane Permeability; Chlorides; Cystic Fibrosis; Diphosphoglyceric Ac

1984
Ferrokinetic and hematologic studies in cystic fibrosis patients.
    The American journal of pediatric hematology/oncology, 1983,Summer, Volume: 5, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Child; Chromium Radioisotopes; Cystic Fibrosis; Diphospho

1983
Inadequate erythroid response to hypoxia in cystic fibrosis.
    The Journal of pediatrics, 1984, Volume: 105, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Biological Availability; Blood Sedimentation; Child; Chil

1984