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2,3-diphosphoglycerate and Cyanosis

2,3-diphosphoglycerate has been researched along with Cyanosis in 3 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Cyanosis: A bluish or purplish discoloration of the skin and mucous membranes due to an increase in the amount of deoxygenated hemoglobin in the blood or a structural defect in the hemoglobin molecule.

Research Excerpts

ExcerptRelevanceReference
"We hypothesized that children with cyanotic congenital heart disease and moderate hypoxemia, as a result of erythrocytosis, and adequate iron stores would have low serum erythropoietin titers, low tissue oxygen delivery, and normal red cell 2,3-diphosphoglycerate (DPG) concentrations."3.67Erythropoietin in cyanotic heart disease. ( Gidding, SS; Stockman, JA, 1988)
"The patient proved to have polycythemia, hemoglobin Kansas, and diabetes mellitus."1.28Hemoglobin Kansas found in a patient with polycythemia. ( Fujisawa, K; Fukuzawa, J; Hayashi, Y; Kawamura, Y; Miyají, T; Morita, K; Ohba, Y; Onodera, S; Sasaki, N; Yamazaki, N, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takagi, Y1
Morita, K1
Fukuzawa, J1
Onodera, S1
Kawamura, Y1
Sasaki, N1
Fujisawa, K1
Ohba, Y1
Miyají, T1
Hayashi, Y1
Yamazaki, N1
Gidding, SS1
Stockman, JA1

Reviews

1 review available for 2,3-diphosphoglycerate and Cyanosis

ArticleYear
[2,3-Diphosphoglycerate (2,3-DPG)].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 12

    Topics: 2,3-Diphosphoglycerate; Anemia; Biomarkers; Cyanosis; Diabetic Ketoacidosis; Heart Failure; Hematolo

2004

Other Studies

2 other studies available for 2,3-diphosphoglycerate and Cyanosis

ArticleYear
Hemoglobin Kansas found in a patient with polycythemia.
    Annals of hematology, 1992, Volume: 65, Issue:5

    Topics: 2,3-Diphosphoglycerate; Cyanosis; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; D

1992
Erythropoietin in cyanotic heart disease.
    American heart journal, 1988, Volume: 116, Issue:1 Pt 1

    Topics: 2,3-Diphosphoglycerate; Child; Child, Preschool; Cyanosis; Diphosphoglyceric Acids; Erythropoietin;

1988