2,3-diphosphoglycerate has been researched along with Critical Illness in 8 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Critical Illness: A disease or state in which death is possible or imminent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To measure red blood cell 2,3-diphosphoglycerate (RBC 2,3-DPG) concentrations in early critical illness; to investigate factors associated with high or low RBC 2,3-DPG levels; to calculate in vivo P50 in patients with early critical illness; and to explore the relationship between RBC 2,3-DPG and intensive care mortality." | 7.73 | Red blood cell 2,3-diphosphoglycerate concentration and in vivo P50 during early critical illness. ( Ibrahim, Eel D; McLellan, SA; Walsh, TS, 2005) |
| "We investigated whether red cell 2,3-diphosphoglycerate (2,3-DPG) concentrations are reduced in critical illness, whether acidaemia, hypophosphataemia or anaemia influence 2,3-DPG, and whether there is any net effect on in vivo P50." | 7.71 | Reduced red cell 2,3-diphosphoglycerate concentrations in critical illness without decreased in vivo P50. ( Clague, A; Koch, D; Morgan, TJ; Morris, D; Purdie, DM, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bateman, RM | 1 |
| Sharpe, MD | 1 |
| Singer, M | 1 |
| Ellis, CG | 1 |
| Ibrahim, Eel D | 1 |
| McLellan, SA | 1 |
| Walsh, TS | 1 |
| Gutierrez, G | 1 |
| Johnson, PA | 1 |
| Bihari, DJ | 1 |
| Raper, RF | 1 |
| Haughton, MA | 1 |
| Fisher, MM | 1 |
| Herkes, RG | 1 |
| Morgan, J | 1 |
| Kanowski, D | 1 |
| Candiani, A | 1 |
| Arduini, R | 1 |
| Gasparetto, A | 1 |
| Kalan, G | 1 |
| Derganc, M | 1 |
| Primoćic, J | 1 |
| Morgan, TJ | 1 |
| Koch, D | 1 |
| Morris, D | 1 |
| Clague, A | 1 |
| Purdie, DM | 1 |
1 review available for 2,3-diphosphoglycerate and Critical Illness
| Article | Year |
|---|---|
The Effect of Sepsis on the Erythrocyte.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antioxidants; Calcium; Cell Shape; Cell Siz | 2017 |
7 other studies available for 2,3-diphosphoglycerate and Critical Illness
| Article | Year |
|---|---|
Red blood cell 2,3-diphosphoglycerate concentration and in vivo P50 during early critical illness.
Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Aged, 80 and over; Blood Gas Analysis; Case-Control | 2005 |
The unpretentious role of 2,3-diphosphoglycerate in critical illness.
Topics: 2,3-Diphosphoglycerate; Critical Illness; Female; Humans; Male; Oxyhemoglobins | 2005 |
A comparison between direct and calculated oxygen saturation in intensive care.
Topics: 2,3-Diphosphoglycerate; Arteries; Blood Gas Analysis; Carbon Dioxide; Critical Care; Critical Illnes | 1993 |
Oxygen availability in critical illness--an investigation using the oxygen status algorithm.
Topics: 2,3-Diphosphoglycerate; Acid-Base Imbalance; Acids; Algorithms; Ambulatory Care; Body Temperature; C | 1995 |
[Use of fructose diphosphate to correct altered oxyphoretic hemoglobin in seriously ill patients].
Topics: 2,3-Diphosphoglycerate; Critical Illness; Fructosediphosphates; Hemodynamics; Humans; Immunologic Fa | 1981 |
Phosphate metabolism in red blood cells of critically ill neonates.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Bacterial Infections; Critical Illness; Erythrocytes | 2000 |
Reduced red cell 2,3-diphosphoglycerate concentrations in critical illness without decreased in vivo P50.
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Blood Gas Analysis; Case-Control Studies; Critical Illness; Ery | 2001 |