2,3-diphosphoglycerate has been researched along with Chronic Illness in 14 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Blood gaseous composition, mechanisms controlling hemoglobin affinity to oxygen and hemoglobin effects of a single captopril dose were assessed in 124 patients with chronic heart failure (CHF)." | 3.67 | [Hemoglobin affinity to oxygen and its correction with captopril in chronic cardiac insufficiency]. ( Blistanova, LS; Griaznov, VV; Kukes, VG, 1989) |
| "1) Patients with chronic hypoxemia, who showed PaO2 less than 60 Torr, had significantly higher P50 than normal subjects." | 1.28 | [Oxyhemoglobin dissociation curve and 2,3-diphosphoglycerate in chronic hypoxemia]. ( Koizumi, M, 1991) |
| "In 80 patients with pulmonary tuberculosis aggravated by stage I-IIB cardiopulmonary insufficiency, the multimodality therapy included vektarion improving the ventilation/perfusion correlations (29 patients) and the combination of metabolic correctors (glutamevit and riboxin) (51 patients)." | 1.28 | [The metabolic correction of erythrocyte function in patients with pulmonary tuberculosis complicated by pulmonary heart failure]. ( Balta, NG; Kaminskaia, GO; Khomenko, AG; Kryzhanovskiĭ, DG; Serebrianaia, BA, 1990) |
| "CHF-associated hypoxemia was shown to be mixed, with the circulatory component prevailing." | 1.28 | [Hemoglobin affinity to oxygen and its correction with captopril in chronic cardiac insufficiency]. ( Blistanova, LS; Griaznov, VV; Kukes, VG, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (28.57) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Puri, BK | 1 |
| Monro, JA | 1 |
| Ramírez-Bajo, MJ | 1 |
| Repiso, A | 1 |
| la Ossa, PP | 1 |
| Bañón-Maneus, E | 1 |
| de Atauri, P | 1 |
| Climent, F | 1 |
| Corrons, JL | 1 |
| Cascante, M | 1 |
| Carreras, J | 1 |
| Rossi, EC | 1 |
| Samaja, M | 1 |
| Brenna, L | 1 |
| Allibardi, S | 1 |
| Cerretelli, P | 1 |
| Ge, RL | 1 |
| Shai, HR | 1 |
| Takeoka, M | 1 |
| Hanaoka, M | 1 |
| Koizumi, T | 1 |
| Matsuzawa, Y | 1 |
| Kubo, K | 1 |
| Kobayashi, T | 1 |
| Koizumi, M | 1 |
| Sisetskiĭ, AP | 1 |
| Artiuk, VP | 1 |
| Sakharchuk, II | 1 |
| Starodub, NF | 1 |
| Isogai, Y | 1 |
| Khomenko, AG | 1 |
| Kryzhanovskiĭ, DG | 1 |
| Kaminskaia, GO | 1 |
| Serebrianaia, BA | 1 |
| Balta, NG | 1 |
| Zapadlo, M | 1 |
| Böswart, J | 1 |
| Petová, J | 1 |
| Hosková, K | 1 |
| German, AK | 1 |
| Negreeva, TA | 1 |
| Kukes, VG | 1 |
| Griaznov, VV | 1 |
| Blistanova, LS | 1 |
| Briguglio, F | 1 |
| Di Marco, V | 1 |
| Circosta, C | 1 |
| Padovano, I | 1 |
| Ragusa, S | 1 |
| Saija, A | 1 |
| Briguglio, E | 1 |
| Aleksandrov, OV | 1 |
| Leont'ev, AV | 1 |
| Pataridze, NO | 1 |
| Kalandarishvili, GG | 1 |
1 review available for 2,3-diphosphoglycerate and Chronic Illness
| Article | Year |
|---|---|
Red cell transfusion therapy in chronic anemia.
Topics: 2,3-Diphosphoglycerate; Anemia; Chronic Disease; Diphosphoglyceric Acids; Erythrocyte Transfusion; H | 1994 |
13 other studies available for 2,3-diphosphoglycerate and Chronic Illness
| Article | Year |
|---|---|
The relationship between plasma vascular endothelial growth factor and erythrocyte 2,3-bisphosphoglycerate: The putative role of chronic hypoxia.
Topics: 2,3-Diphosphoglycerate; Adult; Allosteric Regulation; Biomarkers; Chronic Disease; Enzyme-Linked Imm | 2018 |
Enzymatic and metabolic characterization of the phosphoglycerate kinase deficiency associated with chronic hemolytic anemia caused by the PGK-Barcelona mutation.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Hemolytic; Chronic Disease; Enzyme Stability | 2011 |
Human red blood cell aging at 5,050-m altitude: a role during adaptation to hypoxia.
Topics: 2,3-Diphosphoglycerate; Acclimatization; Adult; Altitude; Chronic Disease; Diphosphoglyceric Acids; | 1993 |
Atrial natriuretic peptide and red cell 2,3-diphosphoglycerate in patients with chronic mountain sickness.
Topics: 2,3-Diphosphoglycerate; Adult; Altitude Sickness; Atrial Natriuretic Factor; Blood Gas Analysis; Cas | 2001 |
[Oxyhemoglobin dissociation curve and 2,3-diphosphoglycerate in chronic hypoxemia].
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Carbon Dioxide; Chronic Disease; Diphosphoglyceric Acids; Human | 1991 |
[The phosphate and methemoglobin content of the erythrocytes in patients with ischemic heart disease].
Topics: 2,3-Diphosphoglycerate; Chronic Disease; Coronary Disease; Diphosphoglyceric Acids; Drug Therapy, Co | 1991 |
[Hemoglobin-oxygen affinity in acute exacerbation of chronic respiratory failure].
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Aged, 80 and over; Chronic Disease; Diphosphoglyceric Acids; Hu | 1990 |
[The metabolic correction of erythrocyte function in patients with pulmonary tuberculosis complicated by pulmonary heart failure].
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Carbon Dioxide; Chronic Disease; Diphosphoglyceric Acids; Drug | 1990 |
The value of umbilical blood 2,3 diphosphoglycerate levels in the diagnosis of chronic fetal hypoxia.
Topics: 2,3-Diphosphoglycerate; Chronic Disease; Diphosphoglyceric Acids; Erythrocytes; Female; Fetal Blood; | 1990 |
[Hemoglobin functional activity in smokers].
Topics: 2,3-Diphosphoglycerate; Adult; Chronic Disease; Diphosphoglyceric Acids; Erythrocyte Count; Erythroc | 1989 |
[Hemoglobin affinity to oxygen and its correction with captopril in chronic cardiac insufficiency].
Topics: 2,3-Diphosphoglycerate; Adult; Aged; Captopril; Carbon Dioxide; Chronic Disease; Diphosphoglyceric A | 1989 |
Metabolic effects of buflomedil hydrochloride.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adenylyl Cyclases; Adult; Aged; Arterial Occlusive D | 1985 |
[Oxygen-transport function of hemoglobin in chronic respiratory failure].
Topics: 2,3-Diphosphoglycerate; Adult; Bronchitis; Chronic Disease; Diphosphoglyceric Acids; Female; Hemoglo | 1987 |