Page last updated: 2024-10-15

2,3-diphosphoglycerate and Cardiac Output, Low

2,3-diphosphoglycerate has been researched along with Cardiac Output, Low in 2 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Cardiac Output, Low: A state of subnormal or depressed cardiac output at rest or during stress. It is a characteristic of CARDIOVASCULAR DISEASES, including congenital, valvular, rheumatic, hypertensive, coronary, and cardiomyopathic. The serious form of low cardiac output is characterized by marked reduction in STROKE VOLUME, and systemic vasoconstriction resulting in cold, pale, and sometimes cyanotic extremities.

Research Excerpts

ExcerptRelevanceReference
"Our data show that in patients with low cardiac output, 2,3-DPG concentration is reduced."1.32Decreased 2,3-diphosphoglycerate concentration in low cardiac output patients and its influence on the determination of in vivo p50. ( Auler, JO; Cestari, IA; Piccioni, MA; Strunz, CM, 2003)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Piccioni, MA1
Cestari, IA1
Strunz, CM1
Auler, JO1
Paltrinieri, S1
Sartorelli, P1
De Vecchi, B1
Agnes, F1

Other Studies

2 other studies available for 2,3-diphosphoglycerate and Cardiac Output, Low

ArticleYear
Decreased 2,3-diphosphoglycerate concentration in low cardiac output patients and its influence on the determination of in vivo p50.
    Artificial organs, 2003, Volume: 27, Issue:8

    Topics: 2,3-Diphosphoglycerate; Adult; Algorithms; Blood Gas Analysis; Cardiac Output, Low; Cardiopulmonary

2003
Metabolic findings in the erythrocytes of cardiopathic and anaemic dogs.
    Journal of comparative pathology, 1998, Volume: 118, Issue:2

    Topics: 2,3-Diphosphoglycerate; Anemia; Anemia, Hemolytic; Animals; Cardiac Output, Low; Dirofilariasis; Dog

1998