2,3-diphosphoglycerate has been researched along with Brain Ischemia in 6 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Brain ischemia was produced in rats by bilateral carotid artery occlusion lasting 60 minutes." | 1.29 | Circulation of red blood cells having high levels of 2,3-bisphosphoglycerate protects rat brain from ischemic metabolic changes during hemodilution. ( Hamasaki, N; Kimura, H; Tomonaga, M; Yamamoto, M, 1995) |
| "Cerebral ischemia was compensated with the increment of cerebral blood flow as a result of the reduction of hematocrit to optimal levels, but the extreme hemodilution induced insufficient oxygen supply to the brain tissue, resulting in a more marked impairment of brain metabolism despite an increase in cerebral blood flow." | 1.29 | Circulation of red blood cells having high levels of 2,3-bisphosphoglycerate protects rat brain from ischemic metabolic changes during hemodilution. ( Hamasaki, N; Kimura, H; Tomonaga, M; Yamamoto, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, L | 1 |
| Ren, C | 1 |
| Li, Y | 1 |
| Gao, C | 1 |
| Li, N | 1 |
| Li, H | 1 |
| Wu, D | 1 |
| He, X | 1 |
| Xia, C | 1 |
| Ji, X | 1 |
| Naruse, S | 1 |
| Horikawa, Y | 1 |
| Tanaka, C | 1 |
| Hirakawa, K | 1 |
| Nishikawa, H | 1 |
| Koizuka, I | 1 |
| Takada, S | 1 |
| Watari, H | 1 |
| Kimura, H | 1 |
| Hamasaki, N | 1 |
| Yamamoto, M | 1 |
| Tomonaga, M | 1 |
| Skulberg, A | 1 |
| Pas'ko, SA | 1 |
| Volosheniuk, TG | 1 |
| Kuzin, VM | 1 |
| Kolesnikova, TI | 1 |
6 other studies available for 2,3-diphosphoglycerate and Brain Ischemia
| Article | Year |
|---|---|
Remote ischemic conditioning enhances oxygen supply to ischemic brain tissue in a mouse model of stroke: Role of elevated 2,3-biphosphoglycerate in erythrocytes.
Topics: 2,3-Diphosphoglycerate; Animals; Brain; Brain Ischemia; Disease Models, Animal; Erythrocytes; Ischem | 2021 |
[In vivo 31P NMR studies on cerebral infarction using topical magnetic resonance (TMR)--time course of high energy phosphorus compounds content in ischemic and recirculated brain].
Topics: 2,3-Diphosphoglycerate; Adenine Nucleotides; Animals; Brain; Brain Ischemia; Diphosphoglyceric Acids | 1983 |
Circulation of red blood cells having high levels of 2,3-bisphosphoglycerate protects rat brain from ischemic metabolic changes during hemodilution.
Topics: 2,3-Diphosphoglycerate; Animals; Brain Ischemia; Diphosphoglyceric Acids; Erythrocyte Transfusion; E | 1995 |
[Can glucose be harmful?].
Topics: 2,3-Diphosphoglycerate; Brain; Brain Ischemia; Diphosphoglyceric Acids; Glucose; Humans; Male; Oxyge | 1994 |
[Causes, sequelae and possible ways of preventing hypophosphatemia in patients with cerebral ischemia].
Topics: 2,3-Diphosphoglycerate; Acute Disease; Adenosine Triphosphate; Brain Ischemia; Calcium-Transporting | 1990 |
[Erythrocyte elasticity and gas metabolism in ischemic stroke patients].
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Brain Ischemia; Carbon Dioxide; Diphosp | 1987 |