Page last updated: 2024-10-15

2,3-diphosphoglycerate and Benign Neoplasms

2,3-diphosphoglycerate has been researched along with Benign Neoplasms in 5 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hitosugi, T1
Zhou, L1
Fan, J1
Elf, S1
Zhang, L1
Xie, J1
Wang, Y2
Gu, TL1
Alečković, M1
LeRoy, G1
Kang, Y1
Kang, HB1
Seo, JH1
Shan, C1
Jin, P1
Gong, W1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Chen, GZ1
Shin, DM1
Khuri, FR1
Boggon, TJ1
Kang, S1
He, C1
Chen, J1
Qu, L1
Triulzi, DJ1
Cai, WS1
Chen, L1
Wang, G1
Prchal, JT1
Pastore, YD1
Vora, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Is Intraoperative Red Blood Cells Transfusion With Different Storage Duration Has Effect on Some Biochemical Parameters in Pediatric Trauma Patients Need Intraoperative Transfusion?[NCT02724605]Phase 2100 participants (Actual)Interventional2016-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for 2,3-diphosphoglycerate and Benign Neoplasms

ArticleYear
Clinical effects of red blood cell storage.
    Cancer control : journal of the Moffitt Cancer Center, 2015, Volume: 22, Issue:1

    Topics: 2,3-Diphosphoglycerate; Cardiac Surgical Procedures; Erythrocyte Transfusion; Erythrocytes; Humans;

2015
Erythropoietin and erythropoiesis: polycythemias due to disruption of oxygen homeostasis.
    The hematology journal : the official journal of the European Haematology Association, 2004, Volume: 5 Suppl 3

    Topics: 2,3-Diphosphoglycerate; Bisphosphoglycerate Mutase; Erythropoiesis; Erythropoietin; Gene Expression

2004
Isozymes of phosphofructokinase.
    Isozymes, 1982, Volume: 6

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Chromosome Mapping;

1982

Other Studies

2 other studies available for 2,3-diphosphoglycerate and Benign Neoplasms

ArticleYear
Tyr26 phosphorylation of PGAM1 provides a metabolic advantage to tumours by stabilizing the active conformation.
    Nature communications, 2013, Volume: 4

    Topics: 2,3-Diphosphoglycerate; Amino Acid Sequence; Animals; Cell Line, Tumor; Cell Proliferation; Enzyme S

2013
Molecular dynamics simulation reveals how phosphorylation of tyrosine 26 of phosphoglycerate mutase 1 upregulates glycolysis and promotes tumor growth.
    Oncotarget, 2017, Feb-14, Volume: 8, Issue:7

    Topics: 2,3-Diphosphoglycerate; Algorithms; Amino Acid Sequence; Glyceric Acids; Glycolysis; Humans; Hydroge

2017