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2,3-diphosphoglycerate and Anemia, Hemolytic, Congenital

2,3-diphosphoglycerate has been researched along with Anemia, Hemolytic, Congenital in 5 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Anemia, Hemolytic, Congenital: Hemolytic anemia due to various intrinsic defects of the erythrocyte.

Research Excerpts

ExcerptRelevanceReference
"Phosphorus-31 nuclear magnetic resonance (NMR) spectra were determined from intact erythrocytes of a patient with homozygous beta-thalassemia and from three patients with pyruvate kinase (PK) deficiency."3.6631P NMR spectroscopy of erythrocytes in congenital hemolytic anemias: detection of heterogeneous erythrocyte populations and quantification of intracellular 2,3-diphosphoglycerate. ( Honig, GR; Labotka, RJ, 1980)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19905 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rotrekl, B1
Prokopová, M1
McGrath, KM1
Collecutt, MF1
Gordon, A1
Sawers, RJ1
Faragher, BS1
Nolan, GR1
Labotka, RJ1
Honig, GR1
Fujii, H1

Other Studies

5 other studies available for 2,3-diphosphoglycerate and Anemia, Hemolytic, Congenital

ArticleYear
[Oxygenation curves in enzymopathic hemolytic anemias].
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1984, Volume: 106

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Hemolytic, Congenital; Anemia, Hemolytic, Co

1984
Dehydrated hereditary stomatocytosis--a report of two families and a review of the literature.
    Pathology, 1984, Volume: 16, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adult; Anemia, Hemolytic, Congenital; Anemia, Hemolytic, Congenital Nonspher

1984
Hereditary xerocytosis. A case history and review of the literature.
    Pathology, 1984, Volume: 16, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adult; Anemia, Hemolytic, Congenital; Anemia, Hemolytic, Congenital Nonspher

1984
31P NMR spectroscopy of erythrocytes in congenital hemolytic anemias: detection of heterogeneous erythrocyte populations and quantification of intracellular 2,3-diphosphoglycerate.
    American journal of hematology, 1980, Volume: 9, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Anemia, Hemolytic, Congenital; Diphosphoglyceric Acids; Erythrocytes;

1980
[Clinical significance of red cell glycolytic intermediate analysis].
    Nihon rinsho. Japanese journal of clinical medicine, 1989, Volume: 48 Suppl

    Topics: 2,3-Diphosphoglycerate; Anemia, Hemolytic, Congenital; Diphosphoglyceric Acids; Erythrocytes; Fructo

1989