2,3-diphosphoglycerate has been researched along with Anemia, Hemolytic, Acquired in 12 studies
2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.
| Excerpt | Relevance | Reference |
|---|---|---|
| "2,3-Diphosphoglycerate was a competitive inhibitor with 6-phosphogluconate (Ki=1." | 1.27 | Inhibition of the pentose phosphate shunt by 2,3-diphosphoglycerate in erythrocyte pyruvate kinase deficiency. ( Lachant, NA; Noble, NA; Tanaka, KR; Tomoda, A, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (75.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ramírez-Bajo, MJ | 1 |
| Repiso, A | 1 |
| la Ossa, PP | 1 |
| Bañón-Maneus, E | 1 |
| de Atauri, P | 1 |
| Climent, F | 1 |
| Corrons, JL | 1 |
| Cascante, M | 1 |
| Carreras, J | 1 |
| BIOERCK, G | 1 |
| BOETTIGER, LE | 1 |
| ORINIUS, E | 1 |
| Somoza, R | 1 |
| Beutler, E | 1 |
| Tomoda, A | 1 |
| Lachant, NA | 4 |
| Noble, NA | 1 |
| Tanaka, KR | 4 |
| Davidson, WD | 1 |
| Larson, PJ | 1 |
| Friedman, DF | 1 |
| Reilly, MP | 1 |
| Kattamis, AC | 1 |
| Asakura, T | 1 |
| Fortina, P | 1 |
| Cohen, AR | 1 |
| Kim, HC | 1 |
| Manno, CS | 1 |
| Paltrinieri, S | 1 |
| Sartorelli, P | 1 |
| De Vecchi, B | 1 |
| Agnes, F | 1 |
| Zerez, CR | 1 |
| Wong, MD | 1 |
| Colombo, MB | 1 |
| Zanella, A | 1 |
| Sirchia, G | 1 |
| Fábryová, V | 1 |
| Goljer, J | 1 |
| Goljer, I | 1 |
| Zalibera, L | 1 |
| Svirklys, LG | 1 |
| O'Sullivan, WJ | 1 |
12 other studies available for 2,3-diphosphoglycerate and Anemia, Hemolytic, Acquired
| Article | Year |
|---|---|
Enzymatic and metabolic characterization of the phosphoglycerate kinase deficiency associated with chronic hemolytic anemia caused by the PGK-Barcelona mutation.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Hemolytic; Chronic Disease; Enzyme Stability | 2011 |
[NONSPHEROCYTIC CONGENITAL HEMOLYTIC ANEMIA WITH INCREASED INTRA-ERYTHROCYTIC CONCENTRATION OF 2,3-DIPHOSPHOGLYCERATE].
Topics: 2,3-Diphosphoglycerate; Anemia; Anemia, Hemolytic; Anemia, Hemolytic, Congenital Nonspherocytic; Dip | 1963 |
Phosphoglycolate phosphatase and 2,3-diphosphoglycerate in red cells of normal and anemic subjects.
Topics: 2,3-Diphosphoglycerate; Adult; Anemia; Anemia, Aplastic; Anemia, Hemolytic; Animals; Diphosphoglycer | 1983 |
Inhibition of the pentose phosphate shunt by 2,3-diphosphoglycerate in erythrocyte pyruvate kinase deficiency.
Topics: 2,3-Diphosphoglycerate; Anemia, Hemolytic; Diphosphoglyceric Acids; Erythrocyte Count; Erythrocytes; | 1983 |
Impaired pentose phosphate shunt function in sickle cell disease: a potential mechanism for increased Heinz body formation and membrane lipid peroxidation.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Hemolytic; Anemia, Sickle Cell; Diphosphogly | 1983 |
The presurgical management with erythrocytapheresis of a patient with a high-oxygen-affinity, unstable Hb variant (Hb Bryn Mawr).
Topics: 2,3-Diphosphoglycerate; Anemia, Hemolytic; Blood Component Removal; Child; Cholelithiasis; Diphospho | 1997 |
Metabolic findings in the erythrocytes of cardiopathic and anaemic dogs.
Topics: 2,3-Diphosphoglycerate; Anemia; Anemia, Hemolytic; Animals; Cardiac Output, Low; Dirofilariasis; Dog | 1998 |
Impaired erythrocyte phosphoribosylpyrophosphate formation in hemolytic anemia due to pyruvate kinase deficiency.
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Hemolytic; Carbon Dioxide; Diphosphoglyceric | 1988 |
2,3-Diphosphoglycerate and 3-phosphoglycerate in red cell pyruvate kinase deficiency.
Topics: 2,3-Diphosphoglycerate; Anemia, Hemolytic; Diphosphoglyceric Acids; Glyceric Acids; Humans; Pyruvate | 1988 |
Dapsone-associated Heinz body hemolytic anemia in a Cambodian woman with hemoglobin E trait.
Topics: 2,3-Diphosphoglycerate; Adult; Anemia, Hemolytic; Cambodia; Dapsone; Diphosphoglyceric Acids; Female | 1987 |
[Use of nuclear magnetic resonance in a study of erythrocyte metabolism].
Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Anemia, Hemolytic; Diphosphoglyceric Acids; Erythroc | 1987 |
Lack of effect of increased 2,3-diphosphoglycerate on flux through the oxidative pathway in phosphoglycerate kinase deficiency.
Topics: 2,3-Diphosphoglycerate; Adult; Anemia, Hemolytic; Child; Diphosphoglyceric Acids; Erythrocytes; Huma | 1985 |