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2,3-diphosphoglycerate and Altitude Sickness

2,3-diphosphoglycerate has been researched along with Altitude Sickness in 11 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Altitude Sickness: Multiple symptoms associated with reduced oxygen at high ALTITUDE.

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's2 (18.18)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sun, K2
Zhang, Y2
D'Alessandro, A2
Nemkov, T2
Song, A2
Wu, H2
Liu, H2
Adebiyi, M1
Huang, A2
Wen, YE1
Bogdanov, MV1
Vila, A1
O'Brien, J1
Kellems, RE2
Dowhan, W1
Subudhi, AW2
Jameson-Van Houten, S2
Julian, CG2
Lovering, AT2
Safo, M1
Hansen, KC2
Roach, RC2
Xia, Y2
Yegutkin, GG1
Li, J1
Cheng, NY1
Edward Wen, Y1
Weng, TT1
Luo, F1
Sun, H1
Karmouty-Quintana, H1
Zhao, B1
Eltzschig, HK1
Blackburn, MR1
Paglia, DE1
Walford, RL1
Wagner, PD1
Wagner, HE1
Groves, BM1
Cymerman, A2
Houston, CS1
Clench, J1
Ferrell, RE1
Schull, WJ1
Moore, LG1
Brewer, GJ1
de Meer, K1
Heymans, HS1
Zijlstra, WG1
Samaja, M1
Mariani, C1
Prestini, A1
Cerretelli, P1
Ge, RL1
Shai, HR1
Takeoka, M1
Hanaoka, M1
Koizumi, T1
Matsuzawa, Y1
Kubo, K1
Kobayashi, T1
Knight, DR1
Devine, JA1
Burse, RL1
Fulco, CS1
Rock, PB1
Tappan, DV1
Messier, AA1
Carhart, H1
Filev, LV1
Mazurov, VI1
Enokhin, SF1
Korotkov, DI1

Reviews

1 review available for 2,3-diphosphoglycerate and Altitude Sickness

ArticleYear
Physical adaptation of children to life at high altitude.
    European journal of pediatrics, 1995, Volume: 154, Issue:4

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Altitude; Altitude Sickness; Animals; Birds; Body

1995

Trials

1 trial available for 2,3-diphosphoglycerate and Altitude Sickness

ArticleYear
Hemoglobin P(50) during a simulated ascent of Mt. Everest, Operation Everest II.
    High altitude medicine & biology, 2007,Spring, Volume: 8, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Adult; Altitude; Altitude Sickness; Atmosphere Ex

2007

Other Studies

9 other studies available for 2,3-diphosphoglycerate and Altitude Sickness

ArticleYear
Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia.
    Nature communications, 2016, 07-15, Volume: 7

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Adult; Altitude Sickness; Animals; Erythrocytes;

2016
Beneficial Role of Erythrocyte Adenosine A2B Receptor-Mediated AMP-Activated Protein Kinase Activation in High-Altitude Hypoxia.
    Circulation, 2016, Aug-02, Volume: 134, Issue:5

    Topics: 2,3-Diphosphoglycerate; 5'-Nucleotidase; Acute Lung Injury; Adaptation, Physiological; Adenosine; Ad

2016
Atypical hematological response to combined calorie restriction and chronic hypoxia in Biosphere 2 crew: a possible link to latent features of hibernation capacity.
    Habitation (Elmsford, N.Y.), 2005, Volume: 10, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adult; Aged; Altitude Sickness; Body Temperature; Caloric Restriction; Diet;

2005
Effect of chronic altitude hypoxia on hematologic and glycolytic parameters.
    The American journal of physiology, 1982, Volume: 242, Issue:5

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Adenosine Triphosphate; Adolescent; Adult; Aged;

1982
Biochemical mechanisms of red blood cell 2,3-diphosphoglycerate increase at high altitude.
    American journal of physical anthropology, 1980, Volume: 53, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Altitude; Altitude Sickness; Diphosphoglyceric Acids; Erythrocytes; F

1980
Acid-base balance and O2 transport at high altitude.
    Acta physiologica Scandinavica, 1997, Volume: 159, Issue:3

    Topics: 2,3-Diphosphoglycerate; Acid-Base Equilibrium; Adaptation, Physiological; Adult; Altitude Sickness;

1997
Atrial natriuretic peptide and red cell 2,3-diphosphoglycerate in patients with chronic mountain sickness.
    Wilderness & environmental medicine, 2001,Spring, Volume: 12, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Altitude Sickness; Atrial Natriuretic Factor; Blood Gas Analysis; Cas

2001
Symptomatology during hypoxic exposure to flame-retardant chamber atmospheres.
    Undersea biomedical research, 1990, Volume: 17, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adult; Altitude Sickness; Atmosphere; Carbon Dioxide; Diphosphoglyceric Acid

1990
[Characteristics of the oxygen-transport function of the erythrocytes in acute altitude hypoxia].
    Voenno-meditsinskii zhurnal, 1989, Issue:10

    Topics: 2,3-Diphosphoglycerate; Acute Disease; Adult; Altitude Sickness; Atmosphere Exposure Chambers; Biolo

1989