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2,3-diphosphoglycerate and Aging

2,3-diphosphoglycerate has been researched along with Aging in 21 studies

2,3-Diphosphoglycerate: A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)
2,3-bisphosphoglyceric acid : A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199016 (76.19)18.7374
1990's2 (9.52)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Qiang, Q1
Manalo, JM1
Sun, H1
Zhang, Y1
Song, A1
Wen, AQ1
Wen, YE1
Chen, C1
Liu, H1
Cui, Y1
Nemkov, T1
Reisz, JA1
Edwards Iii, G1
Perreira, FA1
Kellems, RE1
Soto, C1
D'Alessandro, A1
Xia, Y1
Larrick, JW2
Mendelsohn, AR1
Chemtob, S1
Gibb, W1
Bard, H1
Beutler, E1
West, C1
Mueggler, PA3
Black, JA3
Carpenter, S2
Kumar, R1
Chiero, L1
Rodriguez, D1
Lipschitz, DA1
Udupa, KB1
Milton, KY1
Thompson, CO1
Holter, PH2
Halvorsen, S2
Refsum, HE2
Noble, NA1
Jansen, CA1
Nathanielsz, PW1
Tanaka, KR1
Snyder, LR1
Alvarez-Sala Walther, JL1
Espinós Pérez, D1
Villegas Martínez, A1
Serrano Heranz, R1
Wittmers, LE1
Haller, EW1
Eisinger, J1
Plantamura, A1
Ayavou, T1
Alatyrtsev, VV1
Aleksandrov, AE1
Lekmanov, AU1
Bakanov, MI1
Corda, M1
De Rosa, MC1
Pellegrini, MG1
Sanna, MT1
Olianas, A1
Fais, A1
Manca, L1
Masala, B1
Zappacosta, B1
Ficarra, S1
Castagnola, M1
Giardina, B1
Gallego, C1
Carreras, J1
Weber, RE1
Heath, ME1
White, FN1
Sanengen, T1
Streichman, S1
Avdi, N1
Joffe, G1
Matathias, L1
Tatarsky, I1

Other Studies

21 other studies available for 2,3-diphosphoglycerate and Aging

ArticleYear
Erythrocyte adenosine A2B receptor prevents cognitive and auditory dysfunction by promoting hypoxic and metabolic reprogramming.
    PLoS biology, 2021, Volume: 19, Issue:6

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Auditory Pathways; Bisphosphoglycerate Mutase; Brain; Cochle

2021
Response to Hypoxia in Cognitive Decline.
    Rejuvenation research, 2021, Volume: 24, Issue:4

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Cell Hypoxia; Cognitive Dysfunction; Endothelial Cells; Eryt

2021
Relationship of 2,3-diphosphoglycerate and 2,3-diphosphoglycerate mutase in various mammals.
    Biology of the neonate, 1980, Volume: 38, Issue:1-2

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Animals, Newborn; Bisphosphoglycerate Mutase; Diphosphoglyce

1980
An improved assay and some properties of phosphoglycolate phosphatase.
    Analytical biochemistry, 1980, Jul-15, Volume: 106, Issue:1

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Diphosphoglyceric Acids; Erythrocytes; Glycolates; Humans; O

1980
Postnatal regulation of canine oxygen delivery: control of erythrocyte 2,3-DPG levels.
    The American journal of physiology, 1982, Volume: 242, Issue:4

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Bisphosphoglycerate Mutase; Diphosphoglyceric Acids; Dogs; E

1982
Postnatal regulation of 2,3-DPG in sheep erythrocytes.
    The American journal of physiology, 1983, Volume: 245, Issue:3

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Bisphosphoglycerate Mutase; Diphosphoglyceric Acids; Erythro

1983
Protein phosphotransferases from liver of ageing rats.
    Gerontology, 1984, Volume: 30, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Aging; Animals; Casein Kinases; Cyclic AMP; Diphosph

1984
Postnatal changes in canine erythrocyte pyruvate kinase isozymes.
    Biochemical genetics, 1983, Volume: 21, Issue:7-8

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Diphosphoglyceric Acids; Dogs; Erythrocytes; Female; Fetal B

1983
Effect of age on hematopoiesis in man.
    Blood, 1984, Volume: 63, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adult; Aged; Aging; Anemia; Bone Marrow; Diphosphoglyceric Acids; Erythrocyt

1984
Erythrocyte 2,3-diphosphoglycerate, PO250%, and available oxygen in young rabbits with and without postnatal fall in hemoglobin.
    Pediatric research, 1984, Volume: 18, Issue:2

    Topics: 2,3-Diphosphoglycerate; Aging; Anemia, Hypochromic; Animals; Diphosphoglyceric Acids; Erythrocyte In

1984
Mechanism of red cell 2,3-diphosphoglycerate increase in neonatal lambs.
    Blood, 1983, Volume: 61, Issue:5

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Animals, Newborn; Blood Glucose; Diphosphoglyceric Acids; Er

1983
2,3-diphosphoglycerate in high- and low-altitude populations of the deer mouse.
    Respiration physiology, 1982, Volume: 48, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adaptation, Physiological; Aging; Altitude; Animals; Cold Temperature; Dipho

1982
[Effect of age on the 2,3-diphosphoglycerate content of red blood cells].
    Revista clinica espanola, 1982, May-15, Volume: 165, Issue:3

    Topics: 2,3-Diphosphoglycerate; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Diphosphoglyceric A

1982
The onset and development of polycythaemia in the obese mouse (C57 B1/6J ob/ob).
    Journal of comparative pathology, 1982, Volume: 92, Issue:4

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Blood Glucose; Body Weight; Diphosphoglyceric Acids; Female;

1982
Glycolysis abnormalities in fibromyalgia.
    Journal of the American College of Nutrition, 1994, Volume: 13, Issue:2

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Aging; Diphosphoglyc

1994
[Level of 2,3-diphosphoglycerate and adenosine triphosphate in erythrocytes and acid-base status in adult and newborn rats in acute hypoxia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1995, Volume: 119, Issue:6

    Topics: 2,3-Diphosphoglycerate; Acid-Base Equilibrium; Adenosine Triphosphate; Aging; Animals; Animals, Newb

1995
Adult and fetal haemoglobin J-Sardegna [alpha50(CE8)His-->Asp]: functional and molecular modelling studies.
    The Biochemical journal, 2000, Feb-15, Volume: 346 Pt 1

    Topics: 2,3-Diphosphoglycerate; Adult; Aging; Amino Acid Substitution; Arginine; Aspartic Acid; Binding Site

2000
Fructose 2,6-bisphosphate and glucose 1,6-bisphosphate levels in erythrocytes with high and low 2,3-bisphosphoglycerate content during postnatal development.
    FEBS letters, 1989, Jul-17, Volume: 251, Issue:1-2

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Animals, Newborn; Diphosphoglyceric Acids; Erythrocytes; Fru

1989
Oxygen binding functions of blood and hemoglobin from the Chinese pangolin, Manis pentadactyla: possible implications of burrowing and low body temperature.
    Respiration physiology, 1986, Volume: 64, Issue:1

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Animals, Newborn; Body Temperature; Carbon Dioxide; Diphosph

1986
Erythropoiesis-stimulating factor(s), erythropoiesis and erythrocyte 2,3-diphosphoglycerate in young rabbits with marked post-natal fall in haemoglobin.
    Acta physiologica Scandinavica, 1986, Volume: 126, Issue:4

    Topics: 2,3-Diphosphoglycerate; Aging; Animals; Diphosphoglyceric Acids; Erythrocyte Count; Erythrocytes; Er

1986
Some characteristics of circulating erythrocytes in polycythaemia vera: common features with normal young and foetal red blood cells.
    Scandinavian journal of haematology, 1986, Volume: 36, Issue:1

    Topics: 2,3-Diphosphoglycerate; Adenosine Triphosphate; Aging; Diphosphoglyceric Acids; Erythrocyte Indices;

1986